Adverse Outcome Pathway Development for Assessment of Lung Carcinogenicity by Nanoparticles [0.03%]
纳米颗粒肺致癌性评估的不良结局路径研究法发育
Penny Nymark,Hanna L Karlsson,Sabina Halappanavar et al.
Penny Nymark et al.
Lung cancer, one of the most common and deadly forms of cancer, is in some cases associated with exposure to certain types of particles. With the rise of nanotechnology, there is concern that some engineered nanoparticles may be among such ...
Mace G Barron,Ryan R Otter,Kristin A Connors et al.
Mace G Barron et al.
The ecological threshold of toxicological concern (ecoTTC) is analogous to traditional human health-based TTCs but with derivation and application to ecological species. An ecoTTC is computed from the probability distribution of predicted n...
Research and Development of Microphysiological Systems in Japan Supported by the AMED-MPS Project [0.03%]
日本AMED-MPS项目资助的微生理系统的研究与开发
Seiichi Ishida
Seiichi Ishida
Microphysiological systems (MPS) have been actively developed as a new technology for in vitro toxicity testing platforms in recent years. MPS are culture techniques for the reconstruction of the specific functions of human organs or tissue...
David W Herr
David W Herr
Neuroelectrophysiology is an old science, dating to the 18th century when electrical activity in nerves was discovered. Such discoveries have led to a variety of neurophysiological techniques, ranging from basic neuroscience to clinical app...
Methamphetamine Compromises the Adaptive B Cell-Mediated Immunity to Antigenic Challenge in C57BL/6 Mice [0.03%]
methamphetamine会损害C57BL/6小鼠抗原刺激的适应性B细胞介导的免疫反应
Anum N Mitha,Daniela Chow,Valerie Vaval et al.
Anum N Mitha et al.
Methamphetamine (METH) is a substance of abuse that causes dysregulation of the innate and adaptive immunity in users. B cells are involved in the humoral component of the adaptive immunity by producing and secreting antibodies (Abs). METH ...
Considering intrauterine location in a model of fetal growth restriction after maternal titanium dioxide nanoparticle inhalation [0.03%]
考虑胎盘位置在母体吸入二氧化钛纳米颗粒后胎儿生长受限模型中的作用
J N DErrico,S B Fournier,P A Stapleton
J N DErrico
Fetal growth restriction (FGR) is a condition with several underlying etiologies including gestational disease (e.g., preeclampsia, gestational diabetes) and xenobiotic exposure (e.g., environmental contaminants, pharmaceuticals, recreation...
Investigating the research landscape of chlorinated paraffins over the past ten decades [0.03%]
过去十年氯化石蜡研究领域的进展与趋势探究
Chlorinated paraffins (CPs) are classified as emerging persistent organic pollutants (POPs). Due to their associated environmental and health impacts, these groups of chemicals have been a subject of interest among researchers in the past d...