Martin Lundqvist,Jing Hua,Mikael T Ekvall et al.
Martin Lundqvist et al.
We must recognize that plastics likely constitute a pervasive background in many environments. Beyond their previously documented risks to ecosystems and human health, plastics may also exert unintended influences on laboratory experiments,...
Assessing drinking water treatment efficiency using passive sampling and cell-based bioassays [0.03%]
采用被动采样和细胞生物检测法评估饮用水处理效率
Martin Ezechiáš,Michaela Hegrová Helusová,Gabriela Horáková et al.
Martin Ezechiáš et al.
Introduction: Drinking water treatment plants (DWTPs) are designed to protect public health; however, residual contaminants may persist after treatment and elicit biological effects that are not fully covered by routine c...
Acute anti-proliferative and anti-migratory effects of cannabidiol on C6 rat glioma, SH-SY5Y human neuroblastoma, and HT22 mouse hippocampal neuronal cell cultures [0.03%]
大麻二酚对C6大鼠胶质瘤、SH-SY5Y人神经母细胞瘤和HT22小鼠海马神经元细胞培养的急性抗增殖和抗迁移作用
Kittikun Viwatpinyo,Sujira Mukda,Aktsar Roskiana Ahmad et al.
Kittikun Viwatpinyo et al.
Background: The treatment of central nervous system tumors remains challenging owing to their highly proliferative nature, aggressiveness, and poor prognosis. Additionally, existing treatment methods have several problems...
Examining in vivo effects of silychristin, a potent in vitro inhibitor of thyroid hormone transporter MCT8 [0.03%]
茋类衍生物silychristin体外是强有力的MCT8抑制剂但对在 vivo甲状腺功能没有影响
Kostja Renko,Ryne Thomas,MaryAnn Hawks et al.
Kostja Renko et al.
Thyroid hormone (TH) availability is particularly critical for early brain development. TH transport across the blood-brain barrier is facilitated through two main transmembrane transporters: monocarboxylate transporter 8 (MCT8) and organic...
Protein quality and allergenicity assessment of chia seeds (Salvia hispanica): a molecular perspective on novel food safety [0.03%]
奇亚籽(Salvia hispanica)的蛋白质量及过敏性评估——一种新型食品安全性分子视角
Luisa Calcinai,Sara Cutroneo,Ilaria Puxeddu et al.
Luisa Calcinai et al.
Purpose: This study aimed to assess the protein quality and allergenic potential of chia seeds (Salvia hispanica), introduced in European market as a novel food (Regulation European Union 2015/2283) in 2019. Although chia...
New approach methodologies (NAMs) to support regulatory assessment of developmental immunotoxicity - a new PARC project [0.03%]
支持监管评估的发育免疫毒性新的途径方法(NAMS)——一个新的PARC项目
Nicola M Smith,Véronique M P de Bruijn,Rob J Vandebriel et al.
Nicola M Smith et al.
The current testing strategy for the assessment of developmental immunotoxicity (DIT) in European chemicals regulations has well recognised limitations. In response to these limitations, the Partnership for the Assessment of Risks from Chem...
Transcriptomic and functional profiling of endothelial dysfunction induced by polystyrene nanoplastics [0.03%]
聚苯乙烯纳米塑料诱导内皮功能障碍的转录组和功能谱分析
Joan Martín-Pérez,Aliro Villacorta,Javier Gutiérrez-García et al.
Joan Martín-Pérez et al.
Background: The presence of micro- and nanoplastics (MNPLs) in human blood raises concerns about their vascular impact and their potential contribution to cardiovascular diseases. Endothelial cells are a primary target of...
Comparative evaluation of enzymatic, acidic, and alkaline digestion protocols for organic matrix removal from lyophilized and frozen mussel samples (Mytilus galloprovincialis) [0.03%]
冻干和冷冻 mussel(Mycellius galloprovincialis)样品有机基质去除的酶解、酸解及碱解法的比较评价
S Turmanova,Y Hristov,D Kiryakova et al.
S Turmanova et al.
Efficient removal of organic matter from biological matrices is a critical step in the analysis of microplastics in marine organisms. In this study, enzymatic (Kreon®25,000), acidic (HNO3 + H2O2), and alkaline (KOH + H2O2) digestion protoc...
From beauty to burden: mapping the health and psychosocial impacts of fragrances and cosmetic products use in the UAE [0.03%]
从美丽到负担：阿拉伯联合酋长国香料和化妆品使用对健康和心理社会影响的评估
Sharifa AlBlooshi,Mariam Al Ali,Dana N Abdelrahim et al.
Sharifa AlBlooshi et al.
Background: The dynamic beauty care sector in the Middle East is on an upward trend in the UAE; however, concerns persist about the side effects of this industry, attributed to chemical exposure, which is believed to cont...
Organ-specific bioaccumulation and deterministic health risk assessment of selected heavy metal(loid)s in commercial fish from a southern harbor region (Nagapattinam) [0.03%]
南方港口地区（纳加帕廷姆）商业鱼类特定器官蓄积及几种重金属（类金属）的确定性健康风险评估
Suryapratap Ray,Rahul Vashishth
Suryapratap Ray
Introduction: Heavy metal contamination of coastal waters results in bioaccumulation in fish, posing a significant route of human exposure via seafood consumption. The present study focuses on organ-specific metal distrib...