Uncovering metabolomic dysregulation in Lactuca sativa caused by exposure to nano- and microplastics (NMPs) [0.03%]
纳米和微塑料(NMPs)暴露对莴苣代谢紊乱的影响
María José Gómez-Ramos,Harshit Sahai,Chen Wang et al.
María José Gómez-Ramos et al.
This work investigated the metabolic impact of nano- and microplastics (NMPs) in Lactuca sativa using controlled hydroponic exposures combined with non-targeted high-resolution mass spectrometry metabolomics. Polystyrene NMPs of four partic...
Factors associated with clinical severity in scorpion envenomation: a retrospective cross-sectional study in western Mexico between 2021 and 2025 [0.03%]
墨西哥西部分阶段回顾性横断面研究（2021-2025）中蝎子蜇伤临床严重程度的影响因素分析
Héctor Andrés González-Ruiz,Selene Guadalupe Huerta-Olvera,José Alberto Plascencia-Jiménez et al.
Héctor Andrés González-Ruiz et al.
Introduction: Scorpion envenomation is a major public health concern in Mexico. Although Q9 most of the approximately 300,000 annual cases are resolved without complications, a subset present with moderate or severe manif...
Pesticide-specific case fatality and clinical outcomes among poisoning cases in Tanzania: a retrospective cross-sectional study [0.03%]
坦桑尼亚各类农药中毒的病死率和临床结局：一项回顾性横断面研究
Raphael Mwezi,Joseph Bukalasa,Fredrick Otieno et al.
Raphael Mwezi et al.
Background: Pesticide poisoning remains a major public health challenge in low- and middle-income countries, particularly where highly hazardous pesticides (HHPs) remain accessible and toxicovigilance systems are limited....
Treatment of Saccharomyces cerevisiae with cigarette smoke extract causes vacuolar fragmentation to combat cigarette smoke-induced cellular toxicity [0.03%]
用烟草烟雾提取物处理酿酒酵母菌会导致其液泡片段化以对抗烟草烟雾引起的细胞毒性
Aditya Shukla,Srimonti Sarkar,Alok Kumar Sil
Aditya Shukla
Exposure to cigarette smoke is one of the major risk factors for developing various diseases, such as chronic obstructive pulmonary disease (COPD), cardiovascular disorders, and cancer mediated via cellular oxidative stress and organelle dy...
Oral metal immunotoxicity in rodents: a recoverability-aware systematic review and within-study quantitative reanalysis of splenic SRBC-TDAR [0.03%]
基于恢复性的啮齿动物口服金属免疫毒性系统评价及体内脾脏SRBC-TDAR反应的再分析研究
Iliana C Martínez-Ortiz,Igor Garcia-Atutxa,Carlos Machain-Williams et al.
Iliana C Martínez-Ortiz et al.
Introduction: Public toxicology databases are increasingly used for evidence synthesis, but their value depends not only on the availability of studies but also on whether endpoint-level data can be recovered for reuse. U...
Intestinal toxicity of functionalized polystyrene nanoplastics in NOD2 models of Crohn's disease susceptibility [0.03%]
功能化聚苯乙烯纳米塑料在NOD2型克罗恩病易感模型中的肠道毒性
Manon Dussol,Sandrine Ménard,Margaux Papin et al.
Manon Dussol et al.
The daily use of plastic products leads to exposure of populations via ingestion, which may affect intestinal health. While a wealth of studies has documented the impact of micro- and nanoplastics (MNPLs) on models representing healthy huma...
Case Report: A hypothesis-generating case of gadolinium retention and persistent symptoms after MRI despite normal renal function in a patient with hypermobile Ehlers-Danlos syndrome [0.03%]
个例报告：一名正常肾功能的高弹性型血管性埃勒斯-丹洛斯综合征患者在磁共振成像后出现钆沉积和持续症状的假说生成案例
Cassandra Cox,Abigail Unruh,Brent Wagner et al.
Cassandra Cox et al.
Gadolinium-based contrast agents are commonly used to enhance magnetic resonance imaging. In 2006, Thomas Grobner identified a link between these agents and nephrogenic systemic fibrosis in patients with renal impairment. Gadolinium exposur...
Chronic exposure to mining-contaminated borehole water impairs the entire male reproductive axis: partial mitigation by alpha-lipoic acid in Wistar rats [0.03%]
矿山污染井水的长期暴露损害整个雄性生殖轴：Wistar大鼠α-硫辛酸的部分缓解作用
Festus Toochukwu Okposhi,Collins Nduka Esomchi,Kenneth Tochukwu Onwe et al.
Festus Toochukwu Okposhi et al.
Introduction: Mining activities, industrial discharges, and poor waste management in many developing countries, including Nigeria, have led to widespread contamination of groundwater with mixtures of heavy metals such as ...
Editorial: European partnership on the assessment of risks from chemicals (PARC): continued focus on new approach methodologies (NAMs) and data gap filling [0.03%]
编辑来稿：欧盟化学品风险评估合作计划(PARC)：继续关注新方法(NAM)和数据差距填补
Anna Beronius,Erwin Roggen,Terje Svingen
Anna Beronius
Oxygen-enhanced assembloid-based vascularized intestinal-on-a-chip for radioprotective drug evaluation [0.03%]
基于氧增强器官芯片的血管化肠芯片的放射保护药物评价
Yuting Guo,Meiling Fu,Yuan Pang
Yuting Guo
Background: The intestine plays essential roles in digestion, immunity, and metabolism, but is highly sensitive to ionizing radiation during cancer treatment or environmental exposure. Although three-dimensional intestina...