Evaluating the QEAS-7 questionnaire as a predictor of asbestos burden in lung tissue among lung cancer patients: insights from the AMCANES study [0.03%]
Galo Granados,Antía Ferreiro,Carlos Gómez-Ollés et al.
Galo Granados et al.
Objectives: Asbestos exposure is a known risk factor for lung cancer, and quantifying asbestos bodies (ABs) in lung tissue remains the gold standard for assessing cumulative exposure. However, histological analysis is not...
Effects of predicted Khamisiyah exposure on default mode network resting state functional connectivity in Gulf War Veterans [0.03%]
Linda L Chao,Salvatore Torrisi
Linda L Chao
Introduction: Potentially more than 100,000 US troops were exposed to organophosphorus (OP) nerve agents when an ammunition bunker at Khamisiyah, Iraq was destroyed shortly after the end of the 1991 Gulf War (GW). We prev...
Protective effects of Lagerstroemia speciosa against paracetamol-induced renal and testicular toxicity in rats via antioxidant, anti-inflammatory, and anti-apoptotic mechanisms [0.03%]
Nagham E Elsheshtawy,Engy F Risha,Fatma M Abdelhamid et al.
Nagham E Elsheshtawy et al.
Introduction: Paracetamol (PCM) is widely used as an analgesic; however, at high doses, it is well recognized for its hepatotoxic effects and is increasingly associated with renal and reproductive damage. ...
Perspectives on variability of in vivo toxicology studies: considerations for next-generation toxicology [0.03%]
Agnes L Karmaus,Anna L Kreutz,Oluwakemi Oyetade et al.
Agnes L Karmaus et al.
Introduction: Animal studies have historically informed toxicological testing and safety assessments. However, assessment of the variability in both quantitative and qualitative results has been limited. Biological variab...
Case Report: Delayed gastrointestinal structural complications requiring surgery following massive paint thinner ingestion in an adult [0.03%]
个案报道：成人摄入大量稀释剂后出现晚期胃肠结构并发症并接受手术治疗
Hayeon Lee,Haewon Lee,Min Chang Kang et al.
Hayeon Lee et al.
Background: Paint thinners, which contain volatile aromatic hydrocarbons like toluene and xylene, are primarily associated with acute systemic toxicity (e.g., central nervous system depression, metabolic acidosis) followi...
Invisible victims: rising pediatric cocaine exposures in France (2020-2024) - insights from the national poison center database [0.03%]
隐形受害者：法国儿童可卡因暴露案例的增加（2020-2024）——来自国家中毒中心数据库的见解
Katharina von Fabeck,Mathieu Glaizal,Corinne Schmitt et al.
Katharina von Fabeck et al.
Background: Cocaine use remains prevalent in Europe and has been associated with pediatric exposures through accidental ingestion, passive inhalation, and perinatal or postnatal transmission, potentially leading to signif...
A comparison of honeybee and scorpion venoms as anticancer agents against three different cancer cell lines: lung, colon, and breast cancer [0.03%]
蜜蜂毒液和蝎子毒液作为抗癌药物的比较：三种不同的癌细胞系：肺癌、结肠癌和乳腺癌
Fatma H Galal,Fahad M Alshammari,Abdulrahman S Aldaghmi et al.
Fatma H Galal et al.
Owing to the drawbacks and adverse effects associated with conventional cancer therapies, there is growing interest in identifying effective natural alternatives. In this study, the anticancer potential of honeybee and scorpion venoms was e...
From prediction to adaptation: rethinking the epistemic role of inhalation toxicology [0.03%]
从预测到适应：重新思考吸入毒理学的认识论作用
Samir Dekali
Samir Dekali
Inhalation toxicology has long aimed to predict the health effects of airborne substances before exposure occurs, relying on stable dose-response relationships and well-characterized hazards. This approach becomes increasingly limited when ...
Role of the protease-activated receptor 2 in multi-walled carbon nanotube-induced macrophage polarization ex vivo and airway fibrosis in murine allergic lung disease in vivo [0.03%]
蛋白酶激活受体2在多壁碳纳米管诱导的巨噬细胞极化及小鼠过敏性肺病气道纤维化中的作用
Logan J Tisch,Ryan D Bartone,Silvio Antoniak et al.
Logan J Tisch et al.
Background: Our previous work demonstrated that co-exposure to multi-walled carbon nanotubes (MWCNTs) exacerbates allergic lung disease induced by house dust mite (HDM) extract, and that mice deficient in protease-activat...
Appearance-based computer vision pipeline for multi-animal monitoring of canine activity, behavior and clinical observations [0.03%]
基于外观的计算机视觉管道，用于多动物监测犬类活动、行为及临床观察
Eline Eberhardt,Jef Plochaet,Tanguy Ophoff et al.
Eline Eberhardt et al.
Behavioral monitoring of laboratory animals is essential for evaluating drug safety, yet existing assessments are typically limited to in-room observations by technicians. Here, we introduce our versatile AI model pipeline, composed of inte...