Alcohol-clozapine synergism triggering rhabdomyolysis at subtoxic levels: a case report and literature review [0.03%]
酒精与氯氮平协同作用诱发横纹肌溶解症的病例报告及文献复习
Wenzhen Zhou,Yuxin Sun,Mingcheng Dai et al.
Wenzhen Zhou et al.
Background: While excessive oral intake of clozapine is known to cause severe complications, this case report highlights that even conventional doses of clozapine ingested after alcohol consumption-without reaching toxic ...
Mechanistic read-across comes of age: a comparative appraisal of EFSA 2025 guidance, ECHA's RAAF, and good read-across practice [0.03%]
机制类读过来了成年化：对EFSA 2025指南、ECHA的RAAF和良好读过来了实践的比较评估
Thomas Hartung,Costanza Rovida
Thomas Hartung
Read-across has matured from an expert-driven extrapolation based largely on structural analogy into a rigorously documented, mechanistically informed cornerstone of next-generation risk assessment. Three pivotal frameworks are compared tha...
Erratum: Correction: The impact of perfumes and cosmetic products on human health: a narrative review [0.03%]
致读者一封信：关于“香味化妆品对人类健康的影响：叙述性回顾”的更正声明
Sharifa Alblooshi
Sharifa Alblooshi
[This corrects the article DOI: 10.3389/ftox.2025.1646075.]. Keywords: consumer safety; cosmetics; endocrine...
Published Erratum
Frontiers in toxicology. 2025 Dec 16:7:1713750. DOI:10.3389/ftox.2025.1713750 2025
Enhancing allergenicity risk assessment for novel foods in the EU: insights from the updated EFSA guidance - requirements, knowledge gaps and research needs [0.03%]
欧盟新型食品过敏风险评估的改进——EFSA最新指南带来的启示：要求、知识空白和研究需求
Marcello Laganaro,Anna-Maria Pieger,Alejandra Muñoz-González et al.
Marcello Laganaro et al.
With growing interest in new protein sources, driven by market trends and European Union (EU) food policy priorities, novel proteins are entering the market. These novel foods (NFs) might have the potential of introducing new allergens into...
Comparative evaluation of artificial saliva and complete artificial saliva as solvent vehicles for in vitro toxicity testing of oral tobacco products [0.03%]
口用烟草产品体外毒性检测的人工唾液和完全人工唾液比较评估研究
Xuefei Cao,Mariana T Farcas,Yevgeniya V Prepelitskaya et al.
Xuefei Cao et al.
Background: Oral tobacco-derived nicotine (OTDN) pouches are tobacco-free products and are considered potential reduced-risk alternatives to traditional tobacco products within the tobacco harm reduction framework. Despit...
Simulation of microplastic transport and dispersion based on a three-dimensional hydrodynamic particle-tracking model in the Beibu Gulf [0.03%]
基于三维水动力模型的北部湾微塑料输运与扩散模拟研究
Changhao Sun,Yao Guan,Wenhao Hou et al.
Changhao Sun et al.
The Beibu Gulf, a representative semi-enclosed bay in the South China Sea, experiences microplastic transport and dispersion governed by a complex interplay of monsoons, ocean circulation, and extreme weather events, warranting systematic i...
Cortical microstructural change linked to clinical recovery in subacute delayed encephalopathy after acute carbon monoxide poisoning: a longitudinal case report [0.03%]
一氧化碳急性中毒后亚急性期迟发性脑病临床改善相关的皮层微结构变化：一例报告
Takehiro Tamura,Yuka Fujimoto,Hironobu Nakamura et al.
Takehiro Tamura et al.
Delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) causes disabling cognitive-behavioral symptoms. While cortical atrophy is recognized as a correlate of long-term outcome, links between intracortical microstructural dyna...
Monocyte migration assay using a vascular-on-a-chip model and its utilization for the evaluation of a heated tobacco product [0.03%]
基于血管芯片模型的单核细胞迁移分析及其在加热不燃烧烟草产品评估中的应用研究
Ayaka Hayashida,Atsuko Nozawa,Shigeaki Ito
Ayaka Hayashida
The use of Heated Tobacco Products (HTPs) is expected to have a reduced-risk potential for cardiovascular disease, including atherosclerosis, compared with combustible cigarettes (CCs) Because of the complex relationship between atheroscler...
Thai rice instant granules containing turmeric extract and Phyllanthus emblica fruit pulp: Chronic toxicity and antioxidant profiles in rats and in silico investigation of bioactive compounds [0.03%]
含姜黄和印度醋栗果浆的泰国大米速溶粒剂：大鼠慢性毒性及抗氧化特征和活性成分的计算机模拟研究
Charatda Punvittayagul,Atigan Thongtharb,Sonthaya Umsumarng et al.
Charatda Punvittayagul et al.
Turmeric (Curcuma longa) and Indian gooseberry (Phyllanthus emblica) are widely used for their ethnopharmacological properties, particularly in ASEAN countries. Recently, our group has formulated Thai rice instant granules containing turmer...