Investigating the Trans Effects of IS1 Transposases on Intragenomic DNA Movements in Escherichia coli [0.03%]
Jack William Ord,Zhongge Zhang,Janie Wu et al.
Jack William Ord et al.
Introduction: The transposase protein, InsAB', is the key cytoplastic determinant that catalyzes IS1 movement within a single DNA molecule or between two DNA molecules. Regulation of InsAB' synthesis, its structural chara...
Lakshmi B Reddy,Milton H Saier Jr
Lakshmi B Reddy
The human microbiome is a dynamic, polymicrobial ecosystem that plays an essential role in nutrition, immune development, barrier integrity, and host physiology, acting as a mutualistic partner under balanced conditions. However, its ecolog...
A FocA variant incapable of formate import but retaining formic acid efflux highlights the distinct mechanisms governing bidirectional formate translocation [0.03%]
一种焦谷氨酸变异体无法进口甲酸但保留了甲酸的出口功能，强调了双向甲酸转运的不同机制
Michelle Kammel,Oliver Trebbin,R Gary Sawers
Michelle Kammel
FocA belongs to the formate-nitrite transporter (FNT) superfamily of pentameric membrane proteins, which translocate small, monovalent anions across the cytoplasmic membrane of bacteria, archaea and certain protists. FocA translocates forma...
L-Xylulose reductase A and B from Aspergillus niger have distinct biochemical properties and expression profiles [0.03%]
解脂耶罗沃⽒菌L-木糖醇还原酶A和B具有不同的⽣物化学性质和表达特征
Agata Terebieniec,Astrid Müller,Tania Chroumpi et al.
Agata Terebieniec et al.
D-Xylose and L-arabinose are major components of plant biomass and as such also important carbon sources for most fungi and attractive compounds for biotechnology. Most fungi use the pentose catabolic pathway to convert these sugars through...
Y-complex architecture revisited: Super resolution microscopy to investigate differences in membrane localization for components in Y-complex [0.03%]
重温Y复合物结构：利用超分辨率显微镜研究Y复合物组分在膜定位上的差异
Maximilian Greger,Paul Klemm,Felix Dempwolff et al.
Maximilian Greger et al.
A key factor for the survival of an organism in its habitat is its ability to quickly adapt to changes in its environment on the protein level. One fast and efficient mechanism to influence protein abundance is the regulation of mRNA stabil...
Diverse Metabolic Control of Phosphoglucomutases by Bisphosphorylated Sugars in Heterotrophic Bacteria [0.03%]
异养细菌中二磷酸糖对变位酶的多样化代谢调控
Janette T Alford,Marina Borisova-Mayer,Christoph Mayer et al.
Janette T Alford et al.
Introduction: Phosphoglucomutases (PGM) are crucial for bacterial fitness, environmental survival, pathogenicity, and cell envelope stability, making them potential new targets for combating bacterial infection and transm...
Cooperation and competition were primary driving forces for biological evolution [0.03%]
合作与竞争是生物进化的原始驱动力
Milton H Saier Jr
Milton H Saier Jr
Background: For many years, scientists have accepted Darwin's conclusion that "Survival of the Fittest" involves successful competition with other organisms for life-endowing molecules and conditions. ...
Hub metabolites promote the bioflocculants' production in a biomass-degrading bacterium Pseudomonas boreopolis GO2 [0.03%]
中心代谢产物促进解屑芽孢杆菌Pseudomonas boreopolis GO2生物絮凝剂的产生
Yijie Xu,Jiayin Feng,YuXuan Hu et al.
Yijie Xu et al.
Introduction: The low yield of bioflocculants has been a bottleneck problem that limits their industrial applications. Understanding the metabolic mechanism of bacteria that produce bioflocculants, could provide valuable ...
Development of a Triplex Endpoint PCR Assay for the Detection of SARS-CoV-2: Insights on Cost-Efficiency and Method Design [0.03%]
SARS-CoV-2检测三端点PCR检测试剂盒的研发：成本效益和方法设计的启示
Camelia Vintilă,Razvan Lucian Coșeriu,Anca Delia Mare et al.
Camelia Vintilă et al.
Introduction: Lower respiratory tract infections, including COVID-19, have a substantial global impact, making the development of diagnostic tests crucial. The study aimed to develop a new, accurate, fast, and cost-effect...
Mechanisms of Electroacupuncture in Alleviating Visceral Hypersensitivity in Post-Infectious Irritable Bowel Syndrome Mice: The Role of GDNF Signaling Pathway and Gut Microbiota [0.03%]
电针治疗感染后肠易激综合症小鼠内脏高敏感的机制：脑源性神经营养因子信号通路和肠道菌群的作用
Shiyuan Jiang,Lixia Pei,Lu Chen et al.
Shiyuan Jiang et al.
Introduction: Post-infectious irritable bowel syndrome (PI-IBS) is a functional bowel disease that develops following an acute gastrointestinal infection. Electroacupuncture (EA) can regulate the gut microbiota and allevi...