Global regulation of fungal secondary metabolism in Trichoderma reesei by the transcription factor Ypr1, as revealed by transcriptome analysis [0.03%]
转录因子Ypr1通过调控网络在曲霉稻属菌中调节次生代谢的研究
Jie Yang,Jia-Xiang Li,Fei Zhang et al.
Jie Yang et al.
Trichoderma reesei Rut-C-30 is a well-known robust producer of cellulolytic enzymes, which are used to degrade lignocellulosic biomass for the sustainable production of biofuels and biochemicals. However, studies of its secondary metabolism...
Prospects for engineering Ralstonia eutropha and Zymomonas mobilis for the autotrophic production of 2,3-butanediol from CO2 and H2 [0.03%]
利用Ralstonia eutropha和Zymomonas mobilis以二氧化碳和氢气为原料合成2,3-丁二醇的前景
Hui Wei,Wei Wang,Yat-Chen Chou et al.
Hui Wei et al.
The decarbonization of the chemical industry and a shift toward circular economies because of high global CO2 emissions make CO2 an attractive feedstock for manufacturing chemicals. Moreover, H2 is a low-cost and carbon-free reductant becau...
Carolina E Portero,Yong Han,M Raquel Marchán-Rivadeneira
Carolina E Portero
Numerous studies have investigated the biosynthesis of pyridine heterocycles derived from nicotinic acid. However, metabolic pathways generating pyridine heterocycles in nature remain uninvestigated. Here, we summarize recent contributions ...
Genome editing from Cas9 to IscB: Backwards and forwards towards new breakthroughs [0.03%]
从Cas9到IscB的基因组编辑：回溯与展望新的突破性进展
Zhenxiao Yu,Qunxin She
Zhenxiao Yu
Youming Zhang
Youming Zhang
Potential one-step strategy for PET degradation and PHB biosynthesis through co-cultivation of two engineered microorganisms [0.03%]
通过两种工程微生物共培养实现PET降解和PHB生物合成的一步策略
Pan Liu,Tong Zhang,Yi Zheng et al.
Pan Liu et al.
The management and recycling of plastic waste is a challenging global issue. Polyethylene terephthalate (PET), one of the most widely used synthetic plastics, can be hydrolyzed by a series of enzymes. However, upcycling the resulting monome...
Youming Zhang
Youming Zhang
Integrated engineering of enzymes and microorganisms for improving the efficiency of industrial lignocellulose deconstruction [0.03%]
整合酶和微生物工程提高工业木质纤维素降解效率
Guodong Liu,Yinbo Qu
Guodong Liu
Bioconversion of lignocellulosic biomass to fuels and chemicals represents a new manufacturing paradigm that can help address society's energy, resource, and environmental problems. However, the low efficiency and high cost of lignocellulol...
Regulation of protein thermal stability and its potential application in the development of thermo-attenuated vaccines [0.03%]
蛋白质热稳定性的调控及其在热减毒疫苗开发中的潜在应用
Maofeng Wang,Cancan Wu,Nan Liu et al.
Maofeng Wang et al.
The coronavirus disease 2019 (COVID-19) pandemic has highlighted the importance of developing novel vaccines. An ideal vaccine should trigger an intense immune reaction without causing significant side effects. In this study we found that s...
Cellulolytic characterization of the rumen-isolated Acinetobacter pittii ROBY and design of a potential controlled-release drug delivery system [0.03%]
从瘤胃中分离出的液化沙雷氏菌ROBY的纤维素降解特性及潜在控制释放药物递送系统的设计
Ruken Sariboga,Omer Faruk Sarioglu
Ruken Sariboga
A novel cellulolytic bacterial strain, ROBY, was isolated from a bovine rumen sample using the enrichment culture method. This isolate was found to be Acinetobacter pittii, with >99 % similarity according to 16S rRNA gene sequence analysis....