Key amino acid residues govern the substrate selectivity of the transporter Xltr1p from Trichoderma reesei for glucose, mannose, and galactose [0.03%]
关键氨基酸残基决定了曲霉酸枝菌Xltr1p转运蛋白对葡萄糖、甘露糖和半乳糖的选择性
Wei Ma,Shiyu Yuan,Zixian Wang et al.
Wei Ma et al.
This research identified four amino acid residues (Leu174, Asn297, Tyr301, and Gln291) that contribute to substrate recognition by the high-affinity glucose transporter Xltr1p from Trichoderma reesei. Potential hotspots affecting substrate ...
Functional analysis of the whole CYPome and Fdxome of Streptomyces venezuelae ATCC 15439 [0.03%]
放线单核菌素链霉菌ATCC 15439全细胞色素P450酶系和铁氧还蛋白酶系的功能分析
Shuai Li,Zhong Li,Guoqiang Zhang et al.
Shuai Li et al.
Cytochrome P450 enzymes (CYPs or P450s) and ferredoxins (Fdxs) are ubiquitously distributed in all domains of life. Bacterial P450s are capable of catalyzing various oxidative reactions with two electrons usually donated by Fdxs. Particular...
Immobilization of Thermomyces lanuginosus lipase on metal-organic frameworks and investigation of their catalytic properties and stability [0.03%]
通过金属有机骨架固定化疏水酶及对其催化性质和稳定性的研究
Zeynab Rangraz,Mostafa M Amini,Zohreh Habibi
Zeynab Rangraz
Surface adsorption is a convenient and readily available method for immobilizing enzymes on metal-organic frameworks (MOFs). Metal-organic framework-5 (MOF-5), isoreticular metal-organic frameworks-3 (IRMOF-3), and multivariate analysis of ...
Biofuel production from lignocellulose via thermophile-based consolidated bioprocessing [0.03%]
基于嗜热菌的联合生物加工生产木质纤维素类燃料酒精研究进展
Yilin Le,Mengqi Zhang,Pengju Wu et al.
Yilin Le et al.
The depletion of fossil fuels and their impact on the environment have led to efforts to develop alternative sustainable fuels. While biofuel derived from lignocellulose is considered a sustainable, renewable, and green energy source, enhan...
Zhi-Feng Zhang,Meng Li
Zhi-Feng Zhang
Recently, Chen et al. published their breakthrough results on a marine microbial genomic catalog and genetic potentials in bioprospecting in Nature, providing unprecedented opportunities for development and utilization of genetic resources ...
Genetically engineered bacteria as inflammatory bowel disease therapeutics [0.03%]
基因工程细菌作为炎症性肠病的治疗手段
Zhen-Ping Zou,Xiao-Peng Zhang,Qian Zhang et al.
Zhen-Ping Zou et al.
Inflammatory bowel disease (IBD) is a chronic and recurrent disease caused by immune response disorders that disrupt the intestinal lumen symbiotic ecosystem and dysregulate mucosal immune functions. Current therapies available for IBD prim...
Natural and engineered cyclodipeptides: Biosynthesis, chemical diversity, and engineering strategies for diversification and high-yield bioproduction [0.03%]
天然和工程化的环二肽：生物合成、化学多样性及多样化和高产生物制造策略的工程学方法
Wahyu Setia Widodo,Sonja Billerbeck
Wahyu Setia Widodo
Cyclodipeptides are diverse chemical scaffolds that show a broad range of bioactivities relevant for medicine, agriculture, chemical catalysis, and material sciences. Cyclodipeptides can be synthesized enzymatically through two unrelated en...
Yanbin Liu,Xixian Chen,Congqiang Zhang
Yanbin Liu
Diterpenes, or diterpenoids, are the most abundant and diverse subgroup of terpenoids, the largest family of secondary metabolites. Most diterpenes possess broad biological activities including anti-inflammatory, antiviral, anti-tumoral, an...
Synergistic antifungal mechanism of effective components from essential oil against Penicillium roqueforti [0.03%]
抑制扩展和生物被膜形成的协同抗真菌机制
Fangyuan Zhao,Qianyu Li,Hao Wu et al.
Fangyuan Zhao et al.
Essential oil (EO) has significant antifungal activity. However, there is limited information on the mechanism of the synergistic antifungal effect of the effective components of EO against fungi. In the present study, molecular electrostat...
Two-component system GacS/GacA, a global response regulator of bacterial physiological behaviors [0.03%]
双组分系统GacS/GacA：细菌生理行为的全球响应调控因子
Huihui Song,Yuying Li,Yan Wang
Huihui Song
The signal transduction system of microorganisms helps them adapt to changes in their complex living environment. Two-component system (TCS) is a representative signal transduction system that plays a crucial role in regulating cellular com...