Paris I Brown,Adaobi Ojiakor,Antonio J Chemello et al.
Paris I Brown et al.
AB5-type toxins are a group of secreted protein toxins that are central virulence factors for bacterial pathogens such as Shigella dysenteriae, Vibrio cholerae, Bordetella pertussis, and certain lineages of pathogenic Escherichia coli and S...
A study of the protein-protein interactions in the phycocyanin monomer from Synechocystis sp . PCC 6803 using a bacterial two-hybrid system [0.03%]
利用细菌双杂交系统研究热激鱼腥藻藻蓝蛋白单体的蛋白质间相互作用
Simi Shao,Longsheng Zhao,Pingyi Li et al.
Simi Shao et al.
Investigations into the intramolecular interactions of the native protein in solution are important to understand its structural stability as well as its potential uses in future applications. In this study, we used a bacterial two-hybrid s...
Feifei Chen,Jianhe Xu,Gaowei Zheng
Feifei Chen
A multifunctional biocatalyst EneIRED capable of catalyzing amine-activated conjugate alkene reduction and subsequent reductive amination was discovered. The enzyme realized the coupling of α, β-unsaturated carbonyls with amines to effici...
Metabolic engineering of Streptomyces to enhance the synthesis of valuable natural products [0.03%]
代谢工程改造链霉菌以增强珍贵天然产物的合成
Zuwei Xu,Lihao Ji,Wenxiu Tang et al.
Zuwei Xu et al.
The mycelial bacterium Streptomyces is a workhorse for producing natural products, serving as a key source of drugs and other valuable chemicals. However, its complicated life cycle, silent biosynthetic gene clusters (BGCs), and poorly char...
Engineering for life in toxicity: Key to industrializing microbial synthesis of high energy density fuels [0.03%]
毒性条件下的生命工程是工业规模微生物合成高能量密度燃料的关键
Lijuan Liu,Wenzhi Bao,Xiao Men et al.
Lijuan Liu et al.
With the growing demand for air transportation combined with global concerns about environmental issues and the instability and lack of renewability of the oil market, microbial production of high energy density fuels for jets (bio-jet fuel...
Biochemical characterization of a polyethylene terephthalate hydrolase and design of high-throughput screening for its directed evolution [0.03%]
聚对苯二甲酸乙二醇酯水解酶的生化表征及高效筛选体系构建用于其定向进化研究
Xiaotong Wang,Chaoyi Song,Qingsheng Qi et al.
Xiaotong Wang et al.
Polyethylene terephthalate (PET), one of the most widely used plastics in the world, causes serious environmental pollution. Recently, researchers have focused their efforts on enzymatic degradation of PET, which is an attractive way of deg...
Yan Zhu,Jinxin Zhao,Jian Li
Yan Zhu
The increasing antimicrobial resistance has seriously threatened human health worldwide over the last three decades. This severe medical crisis and the dwindling antibiotic discovery pipeline require the development of novel antimicrobial t...
Achieving simultaneous removal of carbon and nitrogen by an integrated process of anaerobic membrane bioreactor and flow-through biofilm reactor [0.03%]
一种集厌氧膜生物反应器和流动生物膜反应器于一体的碳氮同步去除工艺
Xueshen Wu,Chao Wang,Depeng Wang et al.
Xueshen Wu et al.
In this study, a combined system consisting of an anaerobic membrane bioreactor (AnMBR) and flow-through biofilm reactor/CANON (FTBR/CANON) was developed to simultaneously remove carbon and nitrogen from synthetic livestock wastewater. The ...
Exploring the diversity of microbes and natural products from fungus-growing termite tripartite symbiosis [0.03%]
探求菌圃白蚁三元共生体系中的微生物多样性及其次生代谢产物多样性
Muhammad Shoaib,Ruining Bai,Shuai Li et al.
Muhammad Shoaib et al.
The fungus-growing termite is considered a distinct ecological niche because it involves a tripartite symbiosis between the termite host, gut microflora, and the in vitro fungus Termitomyces, which has led to the expansion of highly organiz...
Identification and application of a strong bidirectional acmN2p promoter from actinomycin D-producing streptomycetes [0.03%]
来源于放线菌素D产生链霉菌的强双向acmN2p启动子的鉴定及应用
Sainan Li,Danfeng Tang,Xu Zhao et al.
Sainan Li et al.
Natural product biosynthesis is controlled at multiple levels. Characterization of naturally occurring promoters has facilitated the study of the synthetic biology of natural products. Herein, we report the discovery of two high-yield actin...