Xiaoying Bian
Xiaoying Bian
The mainstream strategy of genome mining relies on the homologous activation and heterologous expression of target biosynthetic gene clusters (BGCs). However, the efficiency of the current techniques available for new compound discovery har...
Complexity of antibiotic resistance and its impact on gut microbiota dynamics [0.03%]
抗生素抗性的复杂性及其对抗肠道微生物群动态的影响
H Shayista,M N Nagendra Prasad,S Niranjan Raj et al.
H Shayista et al.
The present review explores the influence of the gut microbiota on antibiotic resistance dynamics, particularly those associated with dysbiosis. The improper use of antibiotics can induce resistance in pathogens through various pathways, wh...
BTG13-related metalloenzymes: Atypical non-heme iron-dependent dioxygenases with unusual coordination patterns and catalytic mechanisms [0.03%]
BTG13相关金属酶：具有独特配位模式和催化机制的非血红素铁依赖型二氧 化酶类蛋白质
Zhiwei Deng,Zhenbo Yuan,Zhengshan Luo et al.
Zhiwei Deng et al.
Owing to their diverse coordination patterns and catalytic mechanisms, non-heme iron-dependent dioxygenases catalyze a variety of biochemical reactions involved in the synthesis of numerous natural products and valuable compounds. Recently,...
Chengjie Zhang,Hizar Subthain,Fei Guo et al.
Chengjie Zhang et al.
Terminal deoxynucleotidyl transferase (TdT), a unique DNA polymerase, can elongate DNA by adding deoxynucleotides to the 3' terminal of a DNA chain in a template-independent manner. Owing to their remarkable DNA synthesis activity, TdTs hav...
Establishment and improvement of genetic manipulation tools for Fusobacterium nucleatum [0.03%]
核梭杆菌遗传操作工具的建立与优化
Zhiwei Guan,Hailong Wang,Qiang Feng
Zhiwei Guan
An imbalance in oral microbial homeostasis is significantly associated with the onset and progression of several systemic diseases. Fusobacterium nucleatum, a ubiquitous periodontitis-causing bacterium in the oral cavity, is frequently dete...
Applications of bacteriophages in precision engineering of the human gut microbiome [0.03%]
噬菌体在人类肠道微生物组精准工程中的应用
Xiaoxian Kuang,Juntao Shen,Linggang Zheng et al.
Xiaoxian Kuang et al.
As our understanding of the role of the gut microbiome in human diseases deepens, precision engineering of the gut microbiome using bacteriophages has gained significant attention. Herein, we review the recent advances in bacteriophage-medi...
Modification of essential factors mediating post-translational processing for high-quality protein expression in Penicillium [0.03%]
高水平表达蛋白质的曲霉菌株的工程化改造
Demin Guo,Shengfang Zhao,Jie Chen et al.
Demin Guo et al.
The formation of mature proteins requires complex post-translational modification and processing. Efficient post-translational processing machinery is beneficial for the high-quality expression of proteins. To comprehensively evaluate the r...
The gut virome and human health: From diversity to personalized medicine [0.03%]
肠道病毒组与人类健康：从多样性到个性化医疗
Rahul Harikumar Lathakumari,Leela Kakithakara Vajravelu,Anusha Gopinathan et al.
Rahul Harikumar Lathakumari et al.
The human gut virome plays a crucial role in the gut and overall health; its diversity and regulatory functions influence bacterial populations, metabolism, and immune responses. Bacteriophages (phages) and eukaryotic viruses within the gut...
Erratum to " In vitro characterization of a nitro-forming oxygenase involved in 3-(trans-2'-aminocyclopropyl)alanine biosynthesis" [Engineering Microbiology 2 (2022) 100007] [0.03%]
关于“体外表征参与3-(反式-2'-氨基环丙基)甘氨酸生物合成的硝基形成氧酶”的勘误[工程微生物学 2 (2022) 100007]
Linlin Pang,Weijing Niu,Yuwei Duan et al.
Linlin Pang et al.
[This corrects the article DOI: 10.1016/j.engmic.2021.100007.]. © 2025 The Authors.
Published Erratum
Engineering microbiology. 2025 Mar 13;5(1):100195. DOI:10.1016/j.engmic.2025.100195 2025
Anqi Peng,Weijiao Zhang,Haibo Xiong et al.
Anqi Peng et al.
Small regulatory RNAs (sRNAs) are non-coding RNA molecules that fine-tune various cellular processes and respond to various environmental stimuli. In Bacillus subtilis, the regulatory mechanisms and specific targets of several sRNAs remain ...