Joji M Otaki,Atsuko Tanaka,Euichi Hirose
Joji M Otaki
Butterfly wing eyespots are developmentally determined at the early pupal stage, when prospective eyespot focal cells underneath the pupal cuticle focal spot function as eyespot organizers in the pupal wing tissue. Here, we performed light ...
Schwann cells have a limited window of time in which to initiate myelination signaling during early migration in vivo [0.03%]
施万细胞在体内早期迁移过程中启动髓鞘形成信号的时间窗口有限
Océane El-Hage,Aya Mikdache,Marie-José Boueid et al.
Océane El-Hage et al.
The temporal control of mitotic exit of individual Schwann cells (SCs) is essential for radial sorting and peripheral myelination. However, it remains unknown when, during their multiple rounds of division, SCs initiate myelin signaling in ...
Denis Duboule,Hocine Rekaik
Denis Duboule
2024 not only marked the 100th anniversary of the discovery of the organizer by Hilde Pröscholdt-Mangold and Hans Spemann, but also the 40th anniversary of the discovery of the homeobox, a DNA region encoding a DNA binding peptide present ...
An autocrine synergistic desmin-SPARC network promotes cardiomyogenesis in cardiac stem cells [0.03%]
自分泌协同作用的肌节蛋白-SPARC网络可促进心脏干细胞向心肌细胞分化
Lucia Leitner,Martina Schultheis,Franziska Hofstetter et al.
Lucia Leitner et al.
The mammalian heart contains cardiac stem cells throughout life, but it has not been possible to harness or stimulate these cells to repair damaged myocardium in vivo. Assuming physiological relevance of these cells, which have evolved and ...
Transitions between cooperative and crowding-dominated collective motion in non-jammed MDCK monolayers [0.03%]
非拥挤和合作占主导的二维上皮细胞集体运动之间的转变
Steven J Chisolm,Emily Guo,Vignesh Subramaniam et al.
Steven J Chisolm et al.
Transitions between solid-like and fluid-like states in living tissues have been found in steps of embryonic development and in stages of disease progression. Our current understanding of these transitions has been guided by experimental an...
The evolutionary origin and mechanism of chordate tail regeneration. An ancient tale? [0.03%]
脊索动物尾再生的进化起源与机制。古老的故事？
Wouter Masselink,Prayag Murawala
Wouter Masselink
Chordate tail regeneration represents the remarkable ability of some chordates to partially or completely regenerate a significant portion of their primary body axis. In this review we will discuss the chordate regenerative ability, what is...
Homeotic transformation of tail to limbs: A novel morphogenesis in the framework of self-organization and reprogramming of cell fate during appendage regeneration [0.03%]
尾变四肢：附肢再生过程中细胞命运的自我组织和重编程框架内的新型形态发生现象
Jutshina Hota,Swetamudra Pattnaik,Gunanidhi Sahoo et al.
Jutshina Hota et al.
Homeotic transformation of tail to hindlimbs in anuran tadpoles is a manifestation of the reprogramming of positional information in the event of tail regeneration. Such discovery of homeosis is of particular interest considering its occurr...
Tissue mechanics modulate morphogen signalling to induce the head organiser [0.03%]
组织力学调制形态发生素信号以诱导头部组织者形成
Matyas Bubna-Litic,Guillaume Charras,Roberto Mayor
Matyas Bubna-Litic
Morphogenetic movements and specification of germ layers during gastrulation are key processes that establish the vertebrate body plan. Despite substantial research into the role of tissue mechanics during gastrulation and detailed characte...
LUC7L2 accelerates the growth of liver cancer cells by enhancing DNA damage repair via RRAS [0.03%]
LUC7L2通过RRAS增强DNA损伤修复以促进肝癌细胞增殖
Xinlei Liu,Sijie Xie,Xiaoxue Jiang et al.
Xinlei Liu et al.
Background & objectives: LUC7L2 may be involved in the recognition of non-consensus splice donor sites in association with the U1 snRNP spliceosomal subunit. However, their detailed features and regulatory mechanisms of L...
Hyung Kyu Choi,Sung-Hwan Moon
Hyung Kyu Choi
Research on early human development is crucial for understanding the origins of life and mechanisms underlying disease onset. However, these studies have significant challenges owing to ethical restrictions and technical limitations. Stem c...