Equine adult, fetal and ESC-tenocytes have differential migratory, proliferative and gene expression responses to factors upregulated in the injured tendon [0.03%]
马成人、胎儿和多能干细胞来源的腱细胞对损伤肌腱中上调因子的迁移、增殖和基因表达反应不同
Ross E Beaumont,Emily J Smith,Clara David et al.
Ross E Beaumont et al.
Tendon injuries are a common problem in humans and horses. There is a high re-injury rate in both species due to the poor regeneration of adult tendon and the resulting formation of scar tissue. In contrast, fetal tendon injuries undergo sc...
Organizer formation, organizer maintenance and epithelial cell plasticity in Hydra: Role of the Wnt3/β-catenin/TCF/Sp5/Zic4 gene network [0.03%]
水母中组织者形成、维持及上皮细胞可塑性：Wnt3/β-catenin/TCF/Sp5/Zic4基因网络的作用
Brigitte Galliot,Yvan Wenger
Brigitte Galliot
The experimental and conceptual knowledge in 1909 led to the discovery of the Hydra head organizer through transplantation experiments between pigmented and non-pigmented animals; a discovery followed by numerous transplantations demonstrat...
Jenny Kretzschmar,Katharine Goodwin,Katie McDole
Jenny Kretzschmar
The discovery of the embryonic organizer by Hilde Mangold and Hans Spemann in 1924 was one of the most ground-breaking achievements in the 1900 century for developmental biologists and beyond. Ever since the organizer was first described in...
Jan Stundl,Marianne E Bronner
Jan Stundl
Neural crest induction begins at the neural plate border and involves the intricate interplay of signaling and transcriptional events. In this review, we examine the literature on neural crest induction, focusing primarily on the chick mode...
A tale of two tissues: Patterning of the epidermis through morphogens and their role in establishing tracheal system organization [0.03%]
模式调节子与组织建立：不同上皮的发育故事
L E Sánchez-Cisneros,M F Frutis-Osorio,L D Ríos-Barrera
L E Sánchez-Cisneros
Throughout embryonic development, cells respond to a diverse set of signals and forces, making individual or collective decisions that drive the formation of specialized tissues. The development of these structures is tightly regulated in s...
fos genes in mainly invertebrate model systems: A review of commonalities and some diversities [0.03%]
无脊椎动物模型系统中的Fos基因：一些共同点和不同点的综述
Manuel Zúniga-García,Juan Rafael Riesgo-Escovar
Manuel Zúniga-García
fos genes, transcription factors with a common basic region and leucine zipper domains binding to a consensus DNA sequence (TGA{}TCA), are evolutionarily conserved in eukaryotes. Homologs can be found in many different species from yeast to...
Functional attributes of the anterior mesendoderm in patterning the anterior neural structures during head formation in the mouse [0.03%]
小鼠头部形成过程中前内胚层在前神经结构图案化中的功能属性
Patrick P L Tam,Pragathi Masamsetti
Patrick P L Tam
Induction of the neural ectoderm and the patterning of embryonic brain are the requisite organizing activity for head formation. Studies of loss-of-function mouse mutants that displayed a head truncation phenotype pointed to a key functiona...
Self-organization from organs to embryoids by activin in early amphibian development [0.03%]
Activin介导的早期两栖类动物发育过程中从器官到胚体的自组织现象
Makoto Asashima,Yumeko Satou-Kobayashi,Yoshikazu Haramoto et al.
Makoto Asashima et al.
Embryonic development is a complex self-organizing process orchestrated by a series of regulatory events at the molecular and cellular levels, resulting in the formation of a fully functional organism. This review focuses on activin protein...
Dynamic behavior of cell-cell adhesion factors in collective cell migration [0.03%]
集体细胞迁移中细胞粘附因子的动力学行为
Sayuki Hirano,Kazuhiro Aoki,Naoto Ueno
Sayuki Hirano
Collective cell migration is a fundamental process underlying various biological phenomena, including embryonic development and cancer cell invasion. The cohesive yet flexible movement of cell collectives largely depends on the coordinated ...
Extravillous trophoblasts reverse the decidualization induced increase in matrix production by secreting TGFβ antagonists Emilin-1 and Gremlin-1 [0.03%]
细胞外滋养细胞通过分泌Emilin-1和Gremlin-1拮抗剂逆转基质增生导致的蜕膜化增加现象
Yasir Suhail,Yamin Liu,Junaid Afzal et al.
Yasir Suhail et al.
The maternal-fetal interface has long been considered as a frontier for an evolutionary arms race due to the close juxtaposition of genetically distinct tissues. In hemochorial species with deep placental invasion, including in humans, mate...