fos genes in mainly invertebrate model systems: A review of commonalities and some diversities [0.03%]
无脊椎动物模型系统中的Fos基因：一些共同点和不同点的综述
Manuel Zúniga-García,Juan Rafael Riesgo-Escovar
Manuel Zúniga-García
fos genes, transcription factors with a common basic region and leucine zipper domains binding to a consensus DNA sequence (TGA{}TCA), are evolutionarily conserved in eukaryotes. Homologs can be found in many different species from yeast to...
Functional attributes of the anterior mesendoderm in patterning the anterior neural structures during head formation in the mouse [0.03%]
小鼠头部形成过程中前内胚层在前神经结构图案化中的功能属性
Patrick P L Tam,Pragathi Masamsetti
Patrick P L Tam
Induction of the neural ectoderm and the patterning of embryonic brain are the requisite organizing activity for head formation. Studies of loss-of-function mouse mutants that displayed a head truncation phenotype pointed to a key functiona...
Self-organization from organs to embryoids by activin in early amphibian development [0.03%]
Activin介导的早期两栖类动物发育过程中从器官到胚体的自组织现象
Makoto Asashima,Yumeko Satou-Kobayashi,Yoshikazu Haramoto et al.
Makoto Asashima et al.
Embryonic development is a complex self-organizing process orchestrated by a series of regulatory events at the molecular and cellular levels, resulting in the formation of a fully functional organism. This review focuses on activin protein...
Dynamic behavior of cell-cell adhesion factors in collective cell migration [0.03%]
集体细胞迁移中细胞粘附因子的动力学行为
Sayuki Hirano,Kazuhiro Aoki,Naoto Ueno
Sayuki Hirano
Collective cell migration is a fundamental process underlying various biological phenomena, including embryonic development and cancer cell invasion. The cohesive yet flexible movement of cell collectives largely depends on the coordinated ...
Extravillous trophoblasts reverse the decidualization induced increase in matrix production by secreting TGFβ antagonists Emilin-1 and Gremlin-1 [0.03%]
细胞外滋养细胞通过分泌Emilin-1和Gremlin-1拮抗剂逆转基质增生导致的蜕膜化增加现象
Yasir Suhail,Yamin Liu,Junaid Afzal et al.
Yasir Suhail et al.
The maternal-fetal interface has long been considered as a frontier for an evolutionary arms race due to the close juxtaposition of genetically distinct tissues. In hemochorial species with deep placental invasion, including in humans, mate...
Joji M Otaki,Atsuko Tanaka,Euichi Hirose
Joji M Otaki
Butterfly wing eyespots are developmentally determined at the early pupal stage, when prospective eyespot focal cells underneath the pupal cuticle focal spot function as eyespot organizers in the pupal wing tissue. Here, we performed light ...
Schwann cells have a limited window of time in which to initiate myelination signaling during early migration in vivo [0.03%]
施万细胞在体内早期迁移过程中启动髓鞘形成信号的时间窗口有限
Océane El-Hage,Aya Mikdache,Marie-José Boueid et al.
Océane El-Hage et al.
The temporal control of mitotic exit of individual Schwann cells (SCs) is essential for radial sorting and peripheral myelination. However, it remains unknown when, during their multiple rounds of division, SCs initiate myelin signaling in ...
Denis Duboule,Hocine Rekaik
Denis Duboule
2024 not only marked the 100th anniversary of the discovery of the organizer by Hilde Pröscholdt-Mangold and Hans Spemann, but also the 40th anniversary of the discovery of the homeobox, a DNA region encoding a DNA binding peptide present ...
An autocrine synergistic desmin-SPARC network promotes cardiomyogenesis in cardiac stem cells [0.03%]
自分泌协同作用的肌节蛋白-SPARC网络可促进心脏干细胞向心肌细胞分化
Lucia Leitner,Martina Schultheis,Franziska Hofstetter et al.
Lucia Leitner et al.
The mammalian heart contains cardiac stem cells throughout life, but it has not been possible to harness or stimulate these cells to repair damaged myocardium in vivo. Assuming physiological relevance of these cells, which have evolved and ...
Transitions between cooperative and crowding-dominated collective motion in non-jammed MDCK monolayers [0.03%]
非拥挤和合作占主导的二维上皮细胞集体运动之间的转变
Steven J Chisolm,Emily Guo,Vignesh Subramaniam et al.
Steven J Chisolm et al.
Transitions between solid-like and fluid-like states in living tissues have been found in steps of embryonic development and in stages of disease progression. Our current understanding of these transitions has been guided by experimental an...