Sialoglycoproteins and sialyltransferases: Key regulators of blastocyst formation [0.03%]
糖蛋白和唾液酸转移酶：调控桑椹胚形成的關鍵因素
Pélagie Douchez,Ingrid Fliniaux,Yoshiko Takeda-Uchimura et al.
Pélagie Douchez et al.
Following fertilization, there is an initial period of rapid cell division that leads to the formation of a multicellular structure known as the blastula, or blastocyst. Within this structure, sialic acids play a key role in influencing cel...
Wnt and BMP signaling pathways pattern the anterior neuroectoderm of the indirect-developing hemichordate Ptychodera flava [0.03%]
Wnt和BMP信号通路塑造间接发育环节足动物Ptychodera flava的前神经外胚层图案
Yann Le Petillon,Tzu-Pei Fan,Yi-Chih Chen et al.
Yann Le Petillon et al.
The chordate gastrula organizer establishes Wnt and BMP signaling gradients that are essential for generating the chordate body plan. In non-chordate deuterostomes, including echinoderms and hemichordates, these two signals also contribute ...
LSM14A, an LSM family protein, is dispensable for spermatogenesis and male fertility in mice [0.03%]
LSM家族成员蛋白LSM14A在小鼠雄性生殖力中可有可无
Xu Fan,Ling Yang,Xiao Wang et al.
Xu Fan et al.
The LSM (Like-Smith) family comprises RNA-binding proteins (RBPs) that are key regulators of RNA metabolism. LSM14A, a member of this family (designated Lsm14a in mice), participates in RNA processing within cytoplasmic processing bodies (P...
Extracellular vesicles: A complex array of particles involved in cell-to-cell communication for tissue homeostasis [0.03%]
细胞外囊泡：一种参与组织稳态细胞间通讯的颗粒数组
Natayme Rocha Tartaglia,Lorena Martin-Jaular,Alain Joliot et al.
Natayme Rocha Tartaglia et al.
Communication between cells is an inescapable feature of every multicellular organism, from the coordination of development during embryogenesis to the maintenance of homeostasis throughout adulthood. Extracellular vesicles (EVs) are new an...
Tissue-resident macrophages contribute to ear hole regeneration of early postnatal mice [0.03%]
组织驻留巨噬细胞参与新生小鼠耳孔再生
René Fernando Abarca-Buis,Blanca Alicia Barredo-Prieto,David Garciadiego-Cázares et al.
René Fernando Abarca-Buis et al.
Healing of ear holes made in early postnatal mice represents an accessible model for the study of the regeneration of multiple tissues in mammals. This regenerative process involves three phases: wound healing, blastema formation, and re-di...
Signalling molecules and microenvironment modulation in skin regeneration of chronic wound repair: A cellular perspective [0.03%]
慢性伤口修复过程中皮肤再生的信号分子及微环境调控：细胞层面的视角
Keren Celestina Mendonce,Naveen Palani,P Monisha et al.
Keren Celestina Mendonce et al.
Tissue repair is an intricate biological process involving cellular and molecular mechanisms. These mechanisms coordinate the repair of damaged tissue, relying on the function of several signalling molecules. Growth factors, cytokines, and ...
Morphogenetic constraints in the development of gastruloids: Implications for mouse gastrulation [0.03%]
关于类胚胎发育的形态发生限制：对小鼠原肠运动的意义
U M Fiuza,S Bonavia,P Pascual-Mas et al.
U M Fiuza et al.
Mammalian embryonic size is tightly controlled with checkpoints and compensatory mechanisms correcting size defects. Here, we take advantage of gastruloids, a stem cell embryoid system not subject to most size controls, to study the role of...
Endothelial differentiation of Oral cavity-derived mesenchymal stem/stromal cells [0.03%]
口腔来源的间充质干细胞向内皮细胞分化
Wen Jun Thang
Wen Jun Thang
A rapid construction of vasculature ensures the survival and proper functions of tissue-engineered constructs for oral and craniofacial tissue regeneration. Vascularization achieved via a co-culture system containing endothelial cells (ECs)...
Coordinating tissue development to build body and brain: Lessons from the gastrula organiser and its derivatives [0.03%]
协调组织发育以构建机体和大脑：来自原肠胚形成器及其衍生物的启示
Alexandra Neaverson,Benjamin Steventon
Alexandra Neaverson
The Spemann-Mangold organiser has been a central paradigm in developmental biology for over a century, primarily studied through its ability to induce secondary axes in transplantation experiments. However, how the organiser and its derivat...
Developmental programming by maternal obesity alters offspring lifespan and immune responses in a diet- and sex-specific manner [0.03%]
母体肥胖通过饮食和性别特异性的方式改变后代寿命和免疫反应的表观遗传编程作用研究
Seyhmus Bayar,Lea Seep,Karolina Doubková et al.
Seyhmus Bayar et al.
Maternal obesity is a growing health concern that predisposes offspring to metabolic dysfunction, immune system alterations, and neurodegenerative disorders. To investigate the intergenerational effects of maternal obesity, we used Drosophi...