Inhibition of miR-139-5p by topical JTXK gel promotes healing of Staphylococcus aureus-infected skin wounds [0.03%]
外用JTXK凝胶通过抑制miR-139-5p促进金黄色葡萄球菌感染的皮肤伤口愈合
Weitao Zhang,Xu Qu,Zhang Zhu et al.
Weitao Zhang et al.
Background: The inflammatory skin wound response is regulated by argonaute 2-bound microRNAs (Ago2-miRNAs) such as miR-139-5p, which inhibit transcription of their target mRNAs. Jiang Tang Xiao Ke (JTXK) is a traditional ...
Heart defects and embryonic lethality in Asb2 knock out mice correlate with placental defects [0.03%]
Asb2基因敲除小鼠的心脏缺陷及胚胎致死与胎盘缺陷相关性研究
Seul Gi Park,Eun-Kyoung Kim,Ki-Hoan Nam et al.
Seul Gi Park et al.
Asb2, ankyrin repeat, and SOCS box protein 2 form an E3 ubiquitin ligase complex. Asb2 ubiquitin ligase activity drives the degradation of filamins, which have essential functions in humans. The placenta is a temporary organ that forms duri...
FoxL1+ mesenchymal cells are a critical source of Wnt5a for midgut elongation during mouse embryonic intestinal development [0.03%]
Wnt5a在小鼠胚胎肠发育中期肠道延长过程中FoxL1+间充质细胞的作用
Ayano Kondo,Klaus H Kaestner
Ayano Kondo
Wnt5a is a non-canonical Wnt ligand that is essential for normal embryonic development in mammals. The role of Wnt5a in early intestinal development has been examined in gene ablation models, where Wnt5a-/- mice exhibit strikingly shortened...
FoxL1+ mesenchymal cells are a critical source of Wnt5a for midgut elongation during mouse embryonic intestinal development [0.03%]
Wnt5a在小鼠胚胎肠道发育中肠延长过程中的作用及其信号通路研究
Ayano Kondo,Klaus H Kaestner
Ayano Kondo
Wnt5a is a non-canonical Wnt ligand that is essential for normal embryonic development in mammals. The role of Wnt5a in early intestinal development has been examined in gene ablation models, where Wnt5a-/- mice exhibit strikingly shortened...
MiRNA-26a inhibits myocardial infarction-induced apoptosis by targeting PTEN via JAK/STAT pathways [0.03%]
miRNA-26a通过JAK/STAT信号通路靶向PTEN抑制心肌梗死所致的细胞凋亡
Jianzhong Wang,Qilong Feng,Dongke Liang et al.
Jianzhong Wang et al.
Introduction: Acute myocardial infarction (MI) is a common cause of the morbidity and mortality of cardiovascular diseases in the world. Acute MI lead to cardiovascular output after formation of myocardial ischemia and ci...
Characterization of a new mastermind allele identified from somatic mosaic screen [0.03%]
一个新的Mastermind等位基因的鉴定及表征：来自体细胞性嵌合体筛选的结果
Xinyue Chang,Fengchao Zhang,Haomiao Li et al.
Xinyue Chang et al.
The Notch signaling pathway is highly conserved and regulates various fundamental development events. Activation of Notch signaling relies on production of the Notch intracellular domain (NICD), which assembles a transcription factor comple...
The Drosophila homeodomain transcription factor Homeobrain is involved in the formation of the embryonic protocerebrum and the supraesophageal brain commissure [0.03%]
家蝇Homeobrain同源域转录因子参与胚胎原脑节和咽上脑联合的形成
Dieter Kolb,Petra Kaspar,Christine Klöppel et al.
Dieter Kolb et al.
During the embryonic development of Drosophila melanogaster many transcriptional activators are involved in the formation of the embryonic brain. In our study we show that the transcription factor Homeobrain (Hbn), a member of the 57B homeo...
Moving forward [0.03%]
继往开来
Roberto Mayor
Roberto Mayor