Anteroposterior elongation of the chicken anterior trunk neural tube is hindered by interaction with its surrounding tissues [0.03%]
鸡胚前躯神经管的前后延长受其周围组织的影响
Cathy Danesin,Marina A Ferreira,Pierre Degond et al.
Cathy Danesin et al.
The neural tube is the precursor of the central nervous system. Its early formation and growth are known to be extremely biased along the anteroposterior (AP) axis. Several mechanisms including addition of cells from the tail bud, lateral p...
3D viscoelastic drag forces contribute to cell shape changes during organogenesis in the zebrafish embryo [0.03%]
斑马鱼胚胎器官发生过程中三维粘弹性拖拽力对细胞形态变化的贡献
Paula C Sanematsu,Gonca Erdemci-Tandogan,Himani Patel et al.
Paula C Sanematsu et al.
The left-right organizer in zebrafish embryos, Kupffer's Vesicle (KV), is a simple organ that undergoes programmed asymmetric cell shape changes that are necessary to establish the left-right axis of the embryo. We use simulations and exper...
Myosin cables control the timing of tissue internalization in the Drosophila embryo [0.03%]
果蝇胚胎中的肌球蛋白丝调控组织内陷的时机
Jessica C Yu,Negar Balaghi,Gonca Erdemci-Tandogan et al.
Jessica C Yu et al.
Compartment boundaries prevent cell mixing during animal development. In the early Drosophila embryo, the mesectoderm is a group of glial precursors that separate ectoderm and mesoderm, forming the ventral midline. Mesectoderm cells undergo...
Nicole Gorfinkiel,Alfonso Martinez Arias
Nicole Gorfinkiel
Over the last few years an intense activity in the areas of advanced microscopy and quantitative cell biology has put the focus on the morphogenetic events that shape embryos. The interest in these processes is taking place against the back...
Getting started for migration: A focus on EMT cellular dynamics and mechanics in developmental models [0.03%]
迁移起始:发育模型中上皮-间质转化细胞动力学与力学:focus
Meritxell Font-Noguera,Marianne Montemurro,Corinne Benassayag et al.
Meritxell Font-Noguera et al.
The conversion of epithelial cells into mesenchymal ones, through a process known as epithelial-mesenchymal transition (or EMT) is a reversible process involved in critical steps of animal development as early as gastrulation and throughout...
David R McClay,Jenifer C Croce,Jacob F Warner
David R McClay
Early in animal development many cells are conditionally specified based on observations that those cells can be directed toward alternate fates. The endomesoderm is so named because early specification produces cells that often have been o...
A picket fence function for adherens junctions in epithelial cell polarity [0.03%]
黏附连接的栅栏功能在上皮细胞极性中的作用
Teresa Bonello,Mario Aguilar-Aragon,Alexander Tournier et al.
Teresa Bonello et al.
Adherens junctions are a defining feature of all epithelial cells, providing cell-cell adhesion and contractile ring formation that is essential for cell and tissue morphology. In Drosophila, adherens junctions are concentrated between the ...
Sriivatsan G Rajan,Lynne M Nacke,Jagjot S Dhingra et al.
Sriivatsan G Rajan et al.
Epithelial multiciliated cells (MCCs) use motile cilia to direct external fluid flow, the disruption of which is associated with human diseases in a broad array of organs such as those in the respiratory, reproductive, and renal systems. Wh...
MicroRNA-361 suppresses the biological processes of hepatic stellate cells in HBV-relative hepatic fibrosis by NF-kappaB p65 [0.03%]
miR-361通过NF-κB p65抑制HBV相关肝纤维化中的肝星状细胞的生物学过程
Ge Yu,Han Mu,Hongyuan Zhou et al.
Ge Yu et al.
Background: This research study explores the effect of miR-361 on the activation of immortalized human and mice hepatic stallate cells (HSCs). Methods: ...
Antagonistic regulation controls clathrin-mediated endocytosis: AP2 adaptor facilitation vs restraint from clathrin light chains [0.03%]
拮抗调控控制网格蛋白介导的内吞作用:AP2衔接子促进与网格蛋白轻链抑制之间的相互制衡关系研究
Lisa Redlingshöfer,Frances M Brodsky
Lisa Redlingshöfer
Orchestration of a complex network of protein interactions drives clathrin-mediated endocytosis (CME). A central role for the AP2 adaptor complex beyond cargo recognition and clathrin recruitment has emerged in recent years. It is now appar...