Small molecules induces dorsal root ganglion satellite glial cells to differentiate into sensory neuron-like cells [0.03%]
小分子诱导施万细胞分化成为类似感觉神经元的细胞
Xiaohua Weng,Jinwei Yang,Wei Ma et al.
Xiaohua Weng et al.
The inability of damaged neurons to regenerate poses a significant challenge in the repair of peripheral nerve injuries. Exogenous cell therapies, such as those involving neural stem cells or induced pluripotent stem cells, are limited by i...
Physiological effect of cytokines on adult neurogenesis: a focus on in vivo knock-out studies [0.03%]
细胞因子对成人神经发生生理效应的体内研究:focus on敲除实验
Narjess Haidar,Laure Salvon,Amnah Al-Sayyar et al.
Narjess Haidar et al.
Cytokines, central mediators of immune signaling, have emerged as pivotal regulators of neural stem cell (NSC) biology. Once regarded as immune-privileged, the central nervous system is now recognized as a dynamic site of immune-neural inte...
From initiation to maturation: Mesenchymal stem cells as key facilitators in organoid development [0.03%]
从启动到成熟：间充质干细胞在类器官发育中的关键作用
Shihao Yi,Juan Wen,Tianshun Wang et al.
Shihao Yi et al.
Organoids are three-dimensional cellular structures formed through the self-organization of stem cells that mimic the structure and function of in vivo organs, offering broad applications in biomedical research. Mesenchymal stem cells (MSCs...
Transient versican expression is required for β1-integrin accumulation during podocyte layer morphogenesis in amphibian developing kidney [0.03%]
蛙类发育肾脏过程中足细胞层形态发生期间β1-整联蛋白积累所需的瞬时血管素表达
Isabelle Buisson,Jean-François Riou,Muriel Umbhauer et al.
Isabelle Buisson et al.
The functional organization of the vertebrate nephron is remarkably conserved, yet the morphogenetic processes underlying nephrogenesis vary across species and kidney types. The Xenopus larval kidney, the pronephros, is a non-integrated nep...
A novel role of Mef2a in mitochondrial homeostasis and muscle regeneration during sarcopenia [0.03%]
Mef2a在肌少症肌肉再生中维持线粒体稳态的新作用
Xin Tao,Suhong Zhang,Yue Li et al.
Xin Tao et al.
Sarcopenia, characterized by an age-related decline in skeletal muscle mass and function, is closely associated with mitochondrial dysfunction. This study aimed to explore the role of myocyte enhancer factor 2A (MEF2A) in alleviating sarcop...
Celebrating a century of the Spemann-mangold experiment: Self-organisation in biology [0.03%]
庆祝斯佩曼-孟加德实验一百周年：生物学中的自组织现象
Roberto Mayor
Roberto Mayor
Mechanical conditions preventing live cell extrusion during primary neurulation in amniotes [0.03%]
头索动物活细胞排挤现象在原神经板形成过程中的机械条件研究
Santiago A Bosch-Roascio,Julio A Hernández,Flavio R Zolessi
Santiago A Bosch-Roascio
During primary neurulation in amniote embryos, the neural plate gives rise to the neural tube in a process requiring the coordination of forces at different scales throughout a geometrically complex tissue. The ways in which this process fa...
Sialoglycoproteins and sialyltransferases: Key regulators of blastocyst formation [0.03%]
糖蛋白和唾液酸转移酶：调控桑椹胚形成的關鍵因素
Pélagie Douchez,Ingrid Fliniaux,Yoshiko Takeda-Uchimura et al.
Pélagie Douchez et al.
Following fertilization, there is an initial period of rapid cell division that leads to the formation of a multicellular structure known as the blastula, or blastocyst. Within this structure, sialic acids play a key role in influencing cel...
Wnt and BMP signaling pathways pattern the anterior neuroectoderm of the indirect-developing hemichordate Ptychodera flava [0.03%]
Wnt和BMP信号通路塑造间接发育环节足动物Ptychodera flava的前神经外胚层图案
Yann Le Petillon,Tzu-Pei Fan,Yi-Chih Chen et al.
Yann Le Petillon et al.
The chordate gastrula organizer establishes Wnt and BMP signaling gradients that are essential for generating the chordate body plan. In non-chordate deuterostomes, including echinoderms and hemichordates, these two signals also contribute ...
LSM14A, an LSM family protein, is dispensable for spermatogenesis and male fertility in mice [0.03%]
LSM家族成员蛋白LSM14A在小鼠雄性生殖力中可有可无
Xu Fan,Ling Yang,Xiao Wang et al.
Xu Fan et al.
The LSM (Like-Smith) family comprises RNA-binding proteins (RBPs) that are key regulators of RNA metabolism. LSM14A, a member of this family (designated Lsm14a in mice), participates in RNA processing within cytoplasmic processing bodies (P...