Changes in body shape implicate cuticle stretch in C. elegans growth control [0.03%]
身体形态的变化暗示了秀丽隐杆线虫生长控制中的角质层拉伸作用
Joy Nyaanga,Christina Goss,Gaotian Zhang et al.
Joy Nyaanga et al.
Growth control establishes organism size, requiring mechanisms to sense and adjust growth during development. Studies of single cells revealed that size homeostasis uses distinct control methods. In multicellular organisms, mechanisms that ...
Tissue mechanics in morphogenesis: Active control of tissue material properties to shape living organisms [0.03%]
形态发生中的组织力学：主动控制组织材料属性以塑造生物体
E Trubuil,A D&#x;Angelo,J Solon
E Trubuil
Cellular forces translate into epithelial deformations to shape animal organisms. To set the proper deformations, these forces are modulated in space and time during development. However, several studies have recently highlighted that, in a...
Farhan Chowdhury,Bo Huang,Ning Wang
Farhan Chowdhury
Endogenous and exogenous forces are critical in physiology and pathology of the human body. Increasing evidence suggests that these forces, mechanics, and force-associated signaling are essential in regulating functions of living cells. Her...
John J Williamson
John J Williamson
FGF/MAPK/Ets signaling in Xenopus ectoderm contributes to neural induction and patterning in an autonomous and paracrine manner, respectively [0.03%]
蛙胚外胚层中FGF/MAPK/Ets信号通路自主性和旁分泌性地参与神经诱导和神经轴模式形成
Ikuko Hongo,Harumasa Okamoto
Ikuko Hongo
FGF and anti-BMP signals from the Spemann organizer of mesodermal origin are essential for Xenopus neural development from gastrula ectoderm. However, the detailed cellular and molecular mechanisms of signaling, especially those underlying ...
Knockdown of long non-coding RNA MIR155HG suppresses melanoma cell proliferation, and deregulated MIR155HG in melanoma is associated with M1/M2 balance and macrophage infiltration [0.03%]
长链非编码RNA MIR155HG敲低可抑制黑色素瘤细胞增殖，且MIR155HG在黑色素瘤中的异常表达与M1/M2平衡及巨噬细胞浸润有关
Rui Liu,Xian Sun,Zhen Hu et al.
Rui Liu et al.
This study aimed to address the roles of long non-coding RNA (lncRNA) MIR155HG in melanoma cell proliferation and apoptosis, as well as the roles of deregulated MIR155HG in melanoma cells in regulation M1/M2 macrophage balance and macrophag...
John J Williamson
John J Williamson
The regulation of Msx1 by BMP4/pSmad1/5 signaling is mediated by importin7 in dental mesenchymal cells [0.03%]
BMP4/pSmad1/5信号通过导入素7调控牙囊细胞中Msx1表达
Yawei She,Yue Zhang,Ziqiu Xiao et al.
Yawei She et al.
Msx1 is essential for the maintenance of the odontogenic fate of dental mesenchymal cells, and is regulated by BMP/Smad1/5 signaling in a Smad4-independent manner. However, the exact co-factors that assist pSmad1/5 entering the nucleus to r...
Multi-scale Chimerism: An experimental window on the algorithms of anatomical control [0.03%]
多尺度嵌合体：解剖控制算法的实验窗口
Vasilios Nanos,Michael Levin
Vasilios Nanos
Despite the immense progress in genetics and cell biology, major knowledge gaps remain with respect to prediction and control of the global morphologies that will result from the cooperation of cells with known genomes. The understanding of...
A novel mechanism of the lncRNA PTTG3P/miR-142-5p/JAG1 axis modulating tongue cancer cell phenotypes through the Notch1 signaling [0.03%]
长非编码RNA PTTG3P通过Notch1信号调节舌癌细胞表型的新机制-miR-142-5p/JAG1轴的作用
Tonghan Zhang,Xiaoling Liu,Kui Su et al.
Tonghan Zhang et al.
Tongue cancer is the most prevalent type of oral cancer. Our previous study revealed that JAG1 exerted an oncogenic effect on tongue carcinoma through the JAG1/Notch pathway. In this study, a lncRNA PTTG3P which was upregulated in tongue ca...