Usability of deep learning pipelines for 3D nuclei identification with Stardist and Cellpose [0.03%]
Stardist和Cellpose在三维细胞核识别中的深度学习流程的可用性分析
Giona Kleinberg,Sophia Wang,Ester Comellas et al.
Giona Kleinberg et al.
Segmentation of 3D images to identify cells and their molecular outputs can be difficult and tedious. Machine learning algorithms provide a promising alternative to manual analysis as emerging 3D image processing technology can save conside...
An additive repression mechanism sets the anterior limits of anterior pair-rule stripes 1 [0.03%]
一个累加的阻遏机制设置了前半部成对规则条带1的前方限制
Ludmilla Jurevitz Baltruk,Guilherme Miura Lavezzo,Ariane Machado-Lima et al.
Ludmilla Jurevitz Baltruk et al.
Segments are repeated anatomical units forming the body of insects. In Drosophila, the specification of the body takes place during the blastoderm through the segmentation cascade. Pair-rule genes such as hairy (h), even-skipped (eve), runt...
A physical model for dynamic assembly of human salivary stem/progenitor microstructures [0.03%]
人 saliva干细胞/前体细胞微结构动态组装的物理模型
Yuyang Chen,Danielle Wu,Herbert Levine
Yuyang Chen
The in vitro reconstructions of human salivary glands in service of their eventual medical use represent a challenge for tissue engineering. Here, we present a theoretical approach to the dynamical formation of acinar structures from human ...
The functional verification and analysis of Fugu promoter of cardiac gene tnni1a in zebrafish [0.03%]
刺尾鱼心脏基因tnni1a启动子的斑马鱼功能验证与分析
Yiting Gui,Yawen Zhang,Qi Zhang et al.
Yiting Gui et al.
Troponin I type 1b (Tnni1b) is thought to be a novel isoform that is expressed only in the zebrafish heart. Knocking down of tnni1b can lead to cardiac defects in zebrafish. Although both the zebrafish tnni1b and human troponin I1 (TNNI1) g...
Modulation of DRG neurons response to semaphorin 3A via substrate stiffness [0.03%]
底物刚度对背根节神经元分泌类半导体蛋白3A反应的调节作用研究
Ana Monserrat Vela-Alcantara,Ariadna Rios-Ramirez,Juan Santiago-Garcia et al.
Ana Monserrat Vela-Alcantara et al.
Semaphorin 3A (Sema3a) is a chemotropic protein that acts as a neuronal guidance cue and plays a major role in dorsal root ganglion (DRG) sensory neurons projection during embryo development. The present study evaluated the impact of stiffn...
John J Williamson
John J Williamson
Valencia E Watson,Makala L Faniel,Nourine A Kamili et al.
Valencia E Watson et al.
Alopecia is a non-specific term for hair loss clinically diagnosed by the hair loss pattern and histological analysis of patient scalp biopsies. The immune-mediated alopecia subtypes, including alopecia areata, lichen planopilaris, frontal ...
Mechanical strain breaks planar symmetry in embryonic epithelia via polarized microtubules [0.03%]
机械牵张通过极性微管打破胚胎上皮的平面对称性
Yuan-Hung Chien,Seongjae Kim,Chris Kintner
Yuan-Hung Chien
Mechanical strain can act as a global cue to orient the core planar cell polarity pathway (Fz-PCP) in developing epithelia, but how strain directs a Fz-PCP vector is not known. Here we use live cell imaging of apical microtubules (MTs) and ...
Giselle Espinosa Vásquez,Danilo B Medinas,Hery Urra et al.
Giselle Espinosa Vásquez et al.
The development of the central nervous system requires a series of morphogenetic events that shape brain and spinal cord structures. Several brain regions and neural circuits are formed by differential gene expression patterns and cell migr...
Corrigendum to "Delayed fusion and altered gene expression contribute to semicircular canal defects in Chd7 deficient mice" [Mech. Dev. 129 (9-12) (2012) 308-23 (PMID 22705977)] [0.03%]
“Chd7基因缺陷小鼠前庭蜗管畸形的机制：发育延迟及基因表达异常的作用” 的勘误注释(PMID:22705977)
Elizabeth A Hurd,Joseph A Micucci,Elyse N Reamer et al.
Elizabeth A Hurd et al.
Published Erratum
Cells & development. 2022 Jun:170:203779. DOI:10.1016/j.cdev.2022.203779 2022