Celebrating Spemann-Mangold at 100: An interview with Eddy De Robertis [0.03%]
庆祝Spemann-Mangold百年：与Eddy De Robertis的访谈
John Williamson
John Williamson
John J Williamson
John J Williamson
MiR-29b level-mediated regulation of Klotho methylation via DNMT3A targeting in chronic obstructive pulmonary disease [0.03%]
MiR-29b通过靶向DNMT3A介导的慢性阻塞性肺疾病中Klotho甲基化调节
Jie Qiu,Xiuming Liu,Guilan Yang et al.
Jie Qiu et al.
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease characterized by chronic bronchitis and emphysema. Cigarette smoke extract (CSE) is the predominant cause of COPD. This study aimed to investigate the effects of miR-29b...
5-Azacytidine incorporated skeletal muscle-derived hydrogel promotes rat skeletal muscle regeneration [0.03%]
氮化5-aza胞苷的肌源性水凝胶促进骨骼肌再生
Behnaz Mirza Ahmadi,Afshin Noori,Mohammad Kazemi Ashtiani et al.
Behnaz Mirza Ahmadi et al.
Decellularized skeletal muscle is a promising biomaterial for muscle regeneration due to the mimicking of the natural microenvironment. Previously, it has been reported that 5-Azacytidine (5-Aza), a DNA methyltransferase inhibitor, induces ...
Physical models of notochord cell packing reveal how tension ratios determine morphometry [0.03%]
物理模型揭示了紧张比例如何决定无神经管细胞的形态几何学
Evan J Curcio,Sharon R Lubkin
Evan J Curcio
The physical and geometric aspects of notochords are investigated using a model of finite-length notochords, with interior vacuolated cells arranged in two common packing configurations, and sheath modeled as homogeneous and thin. The key r...
Maimaiti Mikeli,Makoto Fujikawa,Tsutomu Tanabe
Maimaiti Mikeli
We previously reported that knocking down GPD2 (glycerol-3-phosphate dehydrogenase 2), responsible for the glycerol-phosphate shuttle, causes human hepatocarcinoma-derived HuH-7 cells, lowering the cancer stemness. After examining whether G...
Divergent tooth development mechanisms of Mexican tetra fish (Astyanax mexicanus) of Pachón cave origin [0.03%]
墨西哥特斯科 atlanticanz 的帕翁洞穴鱼的离散牙齿发育机制
Devi Atukorallaya,Vikram Bhatia,Jessica Gonzales
Devi Atukorallaya
The Mexican tetra (Astyanax mexicanus) is one of the fresh water teleost fish models in evolutionary developmental biology. The existence of two morphs: eyed, pigmented surface fish and blind depigmented cavefish from multiple cave populati...
Pvr regulates cyst stem cell division in the Drosophila testis niche, and has functions distinct from Egfr [0.03%]
Pvr调控果蝇睾丸生态位中的囊干细胞分裂，并具有与Egfr不同的功能
Nastaran Mues,Kenneth Hammer,Judith Leatherman
Nastaran Mues
Regulation of the rate of stem cell division is one of the key determinants of the abundance of differentiating progeny in stem cell-supported tissues, and mis-regulation can lead to tumorigenesis. The well-studied Drosophila testis niche i...
Inhibition of TGFβ1/Smad pathway by NF-κB induces inflammation leading to poor wound healing in high glucose [0.03%]
高糖通过NF-κB抑制TGFβ1/Sma信号通路诱导炎症导致伤口愈合不良
Fan Gong,Yun Zhang,Suoli Cheng et al.
Fan Gong et al.
This study mainly analyzed the relationship between nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and transforming growth factor-β (TGFβ1)/Smad under high glucose environment and its influence on wound healing. F...
John J Williamson
John J Williamson