Motomu Tanaka,Judith Thoma,Laura Poisa-Beiro et al.
Motomu Tanaka et al.
Adhesion of hematopoietic stem and progenitor cells (HSPCs) to the bone marrow niche plays critical roles in the maintenance of the most primitive HSPCs. The interactions of HSPC-niche interactions are clinically relevant in acute myeloid l...
Temporal and clonal characterization of neural stem cell niche recruitment in the medaka neuromast [0.03%]
斑马鱼神经毛中神经干细胞龛招募的时序及谱系特征分析
Jasmin Onistschenko,Sabrina Kaminsky,Javier Vazquez-Marín et al.
Jasmin Onistschenko et al.
Stem cell populations are defined by their capacity to self-renew and to generate differentiated progeny. These unique characteristics largely depend on the stem cell micro-environment, the so-called stem cell niche. Niches were identified ...
Recent advances in understanding the impact of infection and inflammation on hematopoietic stem and progenitor cells [0.03%]
感染和炎症影响造血干细胞和祖细胞的最新研究进展
Michael D Milsom,Marieke A G Essers
Michael D Milsom
Just over one decade ago, it was discovered that hematopoietic stem cells (HSCs) could directly respond to inflammatory cytokines by mounting a proliferative response thought to mediate the emergency production of mature blood cells. In the...
Deep machine learning for cell segmentation and quantitative analysis of radial plant growth [0.03%]
基于深度机器学习的细胞分割及植物径向生长定量分析模型
Alexandra Zakieva,Lorenzo Cerrone,Thomas Greb
Alexandra Zakieva
Plants produce the major part of terrestrial biomass and are long-term deposits of atmospheric carbon. This capacity is to a large extent due to radial growth of woody species - a process driven by cambium stem cells located in distinct nic...
Differential expression of endothelial protein C receptor (EPCR) in hematopoietic stem and multipotent progenitor cells in young and old mice [0.03%]
年轻和年老小鼠中造血干细胞和多能祖细胞上内皮蛋白C受体(EPCR)的表达差异分析
Dawn S Lin,Andreas Trumpp
Dawn S Lin
Endothelial protein C receptor (EPCR) has emerged as one of the most conserved and reliable surface markers for the prospective identification and isolation of hematopoietic stem cells (HSCs). Prior studies have consistently demonstrated th...
The surface ectoderm exhibits spatially heterogenous tension that correlates with YAP localisation during spinal neural tube closure in mouse embryos [0.03%]
小鼠胚胎脊柱神经管闭合过程中表皮异向张力与YAP亚细胞定位的相关性研究
Abigail R Marshall,Gabriel L Galea,Andrew J Copp et al.
Abigail R Marshall et al.
The single cell layer of surface ectoderm (SE) which overlies the closing neural tube (NT) plays a crucial biomechanical role during mammalian NT closure (NTC), challenging previous assumptions that it is only passive to the force-generatin...
Johanna M S Streubel,Gislene Pereira
Johanna M S Streubel
Centrosomes are microtubule organizing centers involved in chromosome segregation, spindle orientation, cell motility and cilia formation. In recent years, they have also emerged as key modulators of asymmetric cell division. Centrosomes ar...
Andromachi Karakatsani,María I Álvarez-Vergara,Carmen Ruiz de Almodóvar
Andromachi Karakatsani
In the adult rodent brain, neural stem cells (NSCs) reside in the subventricular zone (SVZ) of the lateral ventricles and the subgranular zone (SGZ) of the hippocampus. In these areas, NSCs and their progeny integrate intrinsic signals and ...
Fabio Da Silva,Christof Niehrs
Fabio Da Silva
The neocortex is the site of higher cognitive functions and its development is tightly regulated by cell signalling pathways. Wnt signalling is inexorably linked with neocortex development but its precise role remains unclear. Most studies ...
Cyclopamine targeting hedgehog modulates nuclear control of the osteoblast activity [0.03%]
Cyclopamine靶向刺猬基因调节骨细胞核控机制
Célio J da Costa Fernandes,Marcel Rodrigues Ferreira,Willian Fernando Zambuzzi
Célio J da Costa Fernandes
It is known that cellular events underlying the processes of bone maintenance, remodeling, and repair have their basis in the embryonic production of bone. Shh signaling is widely described developing important morphogenetic control in bone...