Norepinephrine and dopamine Imbalance in the medial frontal gyrus from patients with Alzheimer's disease [0.03%]
阿尔茨海默病患者额叶皮层去甲肾上腺素和多巴胺失衡
Zuleyha Nihan Yurtsever,Silvia Capuani,Michela Fratini et al.
Zuleyha Nihan Yurtsever et al.
Objective: To investigate catecholaminergic alterations in the medial frontal gyrus (MFG) in Alzheimer's disease (AD) patients, including a case with TDP-43 pathology, with a focus on norepinephrine (NE) and dopamine (DA)...
Ondansetron reduces seizures and improves cognitive impairment in a rat model of temporal lobe epilepsy [0.03%]
昂丹司琼可减少癫痫持续状态后颞叶癫痫大鼠模型的发作并改善认知缺陷
Yao Zhang,Ying Sun,Jie Gao et al.
Yao Zhang et al.
Temporal lobe epilepsy (TLE) remains an intractable chronic neurological disorder. Emerging evidence suggests a crucial modulatory role for the 5-hydroxytryptamine 3 receptor (5-HT₃R) in epilepsy. Ondansetron, a selective 5-HT3 receptor an...
Investigation of cholecystokinin-8s-induced hypophagia in neonatal broiler chicks: Roles of central adrenergic and serotonergic systems [0.03%]
胆囊收缩素八肽诱导的幼龄肉鸡摄食减少的研究——肾上腺素能和血清素能系统的作用
Hamed Zarei,Ghazaleh Mahdavi,Emad Shahrabi et al.
Hamed Zarei et al.
Cholecystokinin (CCK) is integral to the central control of appetite, with its sulfated octapeptide isoform (CCK-8s) being particularly relevant. While CCK's anorexigenic effects have been established, the interactions between CCK-8s and ad...
Evaluating the impact of intracerebroventricular norepinephrine on spatial memory in rats: Insights into sporadic Alzheimer's pathogenesis [0.03%]
评价脑室内去甲肾上腺素对大鼠空间记忆的影响：偶发性阿尔茨海默病发病机制的新见解
Mohammad Amir Sharifi Moien,Seyed Javad Saghravanian,Masoud Fereidoni
Mohammad Amir Sharifi Moien
One consequence of stress is the increased release of norepinephrine (NE) in the central nervous system, primarily driven by activation of the sympathetic nervous system. Given the importance of chronic stress in the development and progres...
Cardiovascular risk factors, aging, and incidence of dementia (CAIDE) risk score and its association with cognitive performance and volumetric brain measures in mild cognitive impairment [0.03%]
心血管风险因素、衰老及其与轻度认知障碍的认知表现和脑结构异常的关联研究（CAIDE评分）
Yasaman Abtahi,Marjan Falahati,Sheyda Sharabiani et al.
Yasaman Abtahi et al.
Background: The Cardiovascular Risk Factors, Aging, and Dementia (CAIDE) composite score is a promising measure connecting vascular health to cognitive decline; However, its association with brain imaging findings remains...
Progress on experimental models of neuromyelitis optica spectrum disease [0.03%]
Neuromyelitis光谱疾病的研究进展光学疾患的实验模型
Guo Yawen,Yao Shunyu,Jiang Daiyi et al.
Guo Yawen et al.
Neuromyelitis optica spectrum disease (NMOSD) is an inflammatory demyelinating disease of the central nervous system (CNS) that primarily affects the optic nerve and spinal cord. At present, the etiology and pathogenesis of NMOSD have not b...
Tracing the threads: How toxic metals contribute to neurodegeneration [0.03%]
抽丝剥茧：毒性金属是如何促进神经退行性疾病的发生的
Elyse Wiebe,Zaccheaus Olayiwola,Olamide Adebiyi
Elyse Wiebe
Brain disorders affect more than one in three people globally, representing a leading cause of disability and morbidity. While the etiology of several of these disorders remains elusive, it is increasingly evident that both genetic and envi...
Prenatal exposure to di(2-ethylhexyl) phthalate alters the association of glutamatergic proteins with PTEN in the hippocampus of male rat offspring [0.03%]
孕期暴露于邻苯二甲酸二乙基己酯可改变雄性大鼠海马谷氨酸蛋白与PTEN的相互作用
Natalia Kiknadze,Elene Zhuravliova,David Mikeladze
Natalia Kiknadze
Phthalates are extensively used chemicals known to have adverse effects on human health. Prenatal exposure to phthalates has been associated with potential disruptions in brain development and an elevated susceptibility to cognitive and beh...
Potential protective role of soluble fiber in mitigating tinnitus symptoms: A case-control study [0.03%]
可溶性纤维在缓解耳鸣症状中的潜在保护作用：病例对照研究
Masoomeh Ataei Kachooei,Majid Kamali,Fatemeh Sadat Fahimzad et al.
Masoomeh Ataei Kachooei et al.
Background: Tinnitus, the perception of sound without any external source, affects millions of people worldwide and tends to increase with age. Evidence suggested that dietary fiber may play a critical role in mitigating ...
Early diabetes impairs visual function in mice through altering neuronal activity in the primary visual cortex [0.03%]
糖尿病通过改变初级视觉皮层神经元活性而损害小鼠视功能
Yige Zeng,Chenling Liu,Hanlu Chen et al.
Yige Zeng et al.
Diabetes damages both the retina, leading to retinopathy, and the central visual system, resulting in impaired directional selectivity and color vision in patients without retinopathy. Contrast sensitivity (CS) is a fundamental visual funct...