TNKS1 mediates the PTEN-PI3K/AKT pathway to regulate glycolysis and proliferation in gliomas [0.03%]
TNKS1介导PTEN-PI3K/AKT途径调节胶质瘤糖酵解和增殖
Zhenyan Shi,Danke Shen,Jie Wu et al.
Zhenyan Shi et al.
Objective: To explore the mechanisms by which TNKS1 regulates glycolysis and proliferation in glioma. Methods: Cell viability was asses...
Kehinde O Adeniji,Olumayowa O Igado,Funmilayo E Olopade et al.
Kehinde O Adeniji et al.
Memory consolidation and the preservation of cognitive function are fundamentally influenced by sleep. Lack of sleep affects synaptic plasticity and neurogenesis, as well as oxidative stress and neuroinflammation, all of which impair memory...
Chronic stress alters neurotransmitter co-expression and disrupts context discrimination in a sex-dependent manner [0.03%]
慢性压力以性别依赖的方式改变神经递质的共表达并破坏情境辨别能力
Christopher Mazon,Ryan Betters,Gabriella Salmeron-Ceballos et al.
Christopher Mazon et al.
Stress contributes to neuropsychiatric disorders by altering brain circuits and neurotransmitter signaling, often in a sex-dependent manner. The specifics of these stress-induced changes and their role in the development and perseverance of...
Acupuncture-induced changes in locus coeruleus connectivity and memory improvement in patients with amnestic cognitive impairment [0.03%]
电针刺激对遗忘性认知障碍患者蓝斑功能连接及记忆改善的影响研究
Liyu Hu,Xinbei Li,Juan Ou et al.
Liyu Hu et al.
Background: An increasing number of neuroimaging studies have consistently indicated that the locus coeruleus is associated with cognitive impairment in the early stages of Alzheimer's disease, and the locus coeruleus pla...
Behavioral effects of a chronic envy-like stress paradigm in mice using an adjacent cage model [0.03%]
恒定嫉妒样压力小鼠模型的行为学效应研究
Hiroshi Ueno,Yoshihiro Tanaka,Eriko Kitano et al.
Hiroshi Ueno et al.
Background: Social comparison and envy are significant psychosocial stressors in humans and are known to be involved in the onset and persistence of psychiatric disorders. However, animal models capable of experimentally ...
Endurance training mitigates obesity-induced hippocampal impairment by enhancing neurotrophin signalling, synaptic plasticity, and cellular responses in a female rat model [0.03%]
耐力训练通过提高神经营养素信号、突触可塑性和细胞反应来缓解肥胖引起的海马损伤：雌性大鼠模型研究
Tomáš Kuruc,Karolína Kuchárová,Alexandra Kisucká et al.
Tomáš Kuruc et al.
Obesity-related health issues, including cognitive decline linked to hippocampal neurogenesis and neuroplasticity, are gaining more attention as obesity rates rise worldwide. Physical activity is recognized as a potent stimulator of neurotr...
Exploration and validation of biomarkers for Alzheimer's disease based on GEO database [0.03%]
基于GEO数据库的阿尔茨海默病生物标志物的发掘与验证
Yansha Gan,Jiaojiao Sun,Danting Yang et al.
Yansha Gan et al.
Objectives: The purpose of this study is to leverage bioinformatics techniques to identify differentially expressed genes in Alzheimer's disease (AD), explore potential biomarkers for its early diagnosis, and provide new ...
Crocin alleviates neuronal arborization damage in the basolateral nucleus of the amygdala and dentate gyrus of the hippocampus in a stressed rat [0.03%]
crocin对压力大鼠杏仁核基底外侧核和海马齿状回神经元树突损伤的改善作用
Mohammadali Kargar Barzi,Bahman Jalali Kondori,Gholam Hossein Meftahi
Mohammadali Kargar Barzi
The goal of this research was to explore how crocin can protect neurons in the amygdala and hippocampus, as well as measure its impact on oxidant capacity during chronic immobilization stress in male rats. A group of 24 male Wistar rats, ea...
Development & validation of a simple, sensitive, robust, reproducible & economical spectrofluorimetric method for estimation of taurine in novel chewable gel [0.03%]
一种简单、灵敏、稳健、可重复和经济的分光荧光法用于新型嚼食凝胶中牛磺酸估测的发展与验证方法
Ranjana Bhandari,Niharika Goswami,Yuvraj Patidar et al.
Ranjana Bhandari et al.
Background: Taurine, known as 2-aminoethanesulphonic acid, is a sulfur-containing β-amino acid not incorporated into proteins. However, it takes part in biochemical reactions of significant importance, such as conjugatio...
Relationship between COVID-19 and hypopituitarism: A two-sample Mendelian randomization study [0.03%]
COVID-19与低垂体症关系的两样本孟德尔随机化研究
Xiyang Li,Meichen Tian,Xi Wang et al.
Xiyang Li et al.
Objectives: COVID-19 has been identified as causing damage to the nervous and endocrine systems, with observed effects on hypopituitarism. However, the effects of COVID-19 on hypopituitarism are controversial. In this stu...