Pre-treatment with royal jelly, environmental enrichment, and their combination role in stress induced neurobehavioral deficits in male rats [0.03%]
蜂皇浆预处理、环境丰富干预及其联合作用对雄性大鼠应激所致神经行为缺损的影响
Hakimeh Saadati,Payman Raise-Abdullahi,Alireza Moradi Khankandi et al.
Hakimeh Saadati et al.
Stress plays a pivotal role in anxiety-like disorders and cognitive decline. The present study investigated the potential effects of prior royal jelly supplementation and environmental enrichment against stress-induced anxiety-like behavior...
Evaluating neurochemical changes and associated locomotor activity in a double hit schizophrenia model [0.03%]
评估双打击精神分裂症模型中的神经化学变化及其相关运动活动
Khanyiso Bright Shangase,Mluleki Luvuno,Musa Mabandla
Khanyiso Bright Shangase
Our double hit model is more robust in inducing behavioural and molecular changes involved in the negative and cognitive symptoms of schizophrenia when compared to each single hit model. Disrupted dopamine, glutamate, GABA, and cholinergic ...
EGR2 affects mixed stroke repair through BNIP3L-mediated microglial mitophagy [0.03%]
EGR2通过BNIP3L介导的小胶质细胞线粒体自噬影响混合性卒中修复
Xiujun Zhang,Bensi Zhang,Chun Shi et al.
Xiujun Zhang et al.
Mixed stroke, also known as hemorrhagic infarction or infarction with hemorrhage, presents as a cerebral infarction combined with intracerebral hemorrhage (ICH) on computed tomography (CT) brain scans. ICH is a brain parenchymal hemorrhage ...
Gender-specific gene profiling in Drosophila sporadic model of Parkinson's disease [0.03%]
果蝇帕金森病散发模型中的性别特异性基因表达谱分析
Shreyas M Iyer,Meghana Tare
Shreyas M Iyer
Parkinson's disease (PD) is the second most common neurodegenerative condition characterized by dopaminergic neuronal loss in substantia nigra region of the brain. Sporadic PD cases have been attributed to exposure to toxins, such as roteno...
Perioperative use of eculizumab in patients with thymoma-associated myasthenia gravis: A preliminary case series of five patients [0.03%]
依库珠单抗在胸腺瘤相关重症肌无力患者围手术期的应用：5例病例系列报告
Yaotong Ou,Yi Wen,Yiyi Liu et al.
Yaotong Ou et al.
Patients with myasthenia gravis (MG) are at risk of myasthenic crisis (MC) or clinical deterioration following thymectomy. Although eculizumab has demonstrated efficacy in the management of MC, its role in perioperative optimization for thy...
Prediction of early neurological deterioration using quantitative susceptibility mapping in small artery occlusion ischemic stroke [0.03%]
定量磁敏感加权成像预测小动脉闭塞型缺血性卒中的早期神经功能恶化风险
Xuelian Tang,Yanhua Yu,Yusheng Yu et al.
Xuelian Tang et al.
Background: Approximately 20-30% of ischemic stroke patients with small artery occlusion (SAO) experience early neurological deterioration (END) after stroke onset, which is associated with a poor prognosis. Our aim was t...
TGF-β1 modulates PFC glial cell activation to facilitate exercise-induced analgesia in mice with spared nerve injury [0.03%]
TGF-β1通过调节 spared 髓鞘神经损伤小鼠前额叶胶质细胞活化来促进运动介导的痛觉减退作用
Yan Kong,Junqi Wu,Xinzheng Sun et al.
Yan Kong et al.
Background: The prefrontal cortex (PFC) is a key brain region involved in pain-related processing. Exercise has been recognized as an effective non-pharmacological intervention for alleviating neuropathic pain; however, w...
Lipid-associated macrophage remodeling is present in the tumor microenvironment after high-grade glioma recurrence [0.03%]
高级别胶质瘤复发后肿瘤微环境中存在与脂质相关的巨噬细胞重塑现象
Guanchao Xie,Hongqing Cai,Fuxing Zuo et al.
Guanchao Xie et al.
Background: The inevitable recurrence of most high-grade gliomas (HGG) despite aggressive treatment poses a significant challenge to clinicians. Recently it has been found that exploring the characteristics of cell popula...
Medullary dorsal horn neurons activated during voluntary diving express neurotransmitter receptors for glutamate and substance P [0.03%]
参与自主潜水的延髓背角神经元表达谷氨酸和P物质受体
P F McCulloch,K M DiNovo
P F McCulloch
The diving response is a cardiorespiratory reflex characterized by apnea, bradycardia and increased peripheral vascular resistance when animals submerge underwater. Afferent information initiating this reflex response projects from the nasa...
Ruonan Cao,Chaoran Liu,Zhihui Liu et al.
Ruonan Cao et al.
Neuroglial cells serve as the myelinating cells in the central nervous system and are essential for axonal integrity and function. Following a stroke, progressive loss of myelin occurs in white matter regions distal to the infarct core, con...