DNA methylation-estimated phenotypes, telomere length, aging and risk of intracranial aneurysms: Evidence from genetic studies [0.03%]
基于遗传学研究的表观遗传修饰与颅内动脉瘤发病相关性分析
Xin Zhang,Aierpati Maimaiti,Meixia Xie et al.
Xin Zhang et al.
Background: The risk of intracranial aneurysm (IA) is increased in older population, suggesting a role for aging. To evaluate the association of genetic variants linked to DNA methylation-estimated phenotypes, telomere le...
Effects of ethanol exposure in neonatal mice on retinoic acid signaling in forebrain neurons and astrocytes [0.03%]
乙醇暴露对小鼠脑皮层神经元和星形胶质细胞视黄酸信号的影响研究
Mariko Saito,Jungann Park,Anusha Nalluri et al.
Mariko Saito et al.
Toxicity of prenatal ethanol leading to fetal alcohol spectrum disorders (FASDs) has been linked to disturbances in retinoic acid (RA) signaling necessary for embryonic development. While ethanol exposure in the postnatal day 7 (P7) mice, w...
Research on stem cell therapy for brain injury: A bibliometric and visual analysis (2009-2025) [0.03%]
脑损伤干细胞治疗研究的 bibliometrix 可视化分析(2009-2025)
Chen Xiong,Zixin Zuo,Ziyang Kuang et al.
Chen Xiong et al.
Background: Brain injury refers to a state in which the brain cannot function due to an abnormality in the nerve tissue from internal or external causes. However, existing treatments for brain injury are largely unable to...
Piezoelectric cold atmospheric plasma modulates neurogenic cell proliferation and differentiation via cross-signaling [0.03%]
压电冷等离子体通过交叉信号调节神经源性细胞增殖和分化
Haitao Zhang,Boyu Cai,Jiaojiao Li et al.
Haitao Zhang et al.
Cold atmospheric plasma regulates cell fate by modulating cellular oxidative stress levels, making it a promising new therapy in the field of cell bioengineering. While the regulatory effects and potential molecular mechanisms of the novel ...
A refined porcine lumbar spinal cord injury model facilitating postoperative care [0.03%]
一种精制的猪腰椎脊髓损伤模型促进术后护理
N Prieur-Blanc,S Trama,A Mangini et al.
N Prieur-Blanc et al.
Background: Pigs exhibit strong anatomical and neurological similarities to humans, making them valuable translational models for spinal cord injury (SCI) research. While most porcine SCI models target thoracic levels, th...
Immunoglobulin G exacerbates endothelial-microglial crosstalk, promoting secondary injury in high-altitude cerebral edema [0.03%]
免疫球蛋白G加重内皮细胞-小胶质细胞的相互作用从而促进高原脑水肿二期损伤形成
Yan Xue,Meijuan Qian,Dongzhi Wang et al.
Yan Xue et al.
Hypobaric hypoxia (HH)-induced blood-brain barrier (BBB) disruption is a critical pathological event in high-altitude cerebral edema (HACE). However, the mechanistic role of extravasated immunoglobulin G (IgG) in this process remains insuff...
Identification of EEG features during status epilepticus for prediction of emergent epilepsy phenotype in the mouse intra-amygdala kainic acid model using supervised learning [0.03%]
基于监督学习的身份识别癫痫持续状态期间的EEG特征以预测老鼠海马内侧杏仁核KA模型中癫痫紧急表型
Syed Muhammad Raza Abidi,Omar Mamad,Jordan Higgins et al.
Syed Muhammad Raza Abidi et al.
Preclinical animal models are essential for investigating epilepsy mechanisms and evaluating novel therapies. In rodents, epilepsy can be induced by status epilepticus, leading to later spontaneous recurrent seizures (SRSs). However, inter-...
Tilting the balance toward motor symptoms: Determinants of caregiver burden in late-stage Parkinson's disease [0.03%]
晚期帕金森病中护理负担的决定因素:偏向运动症状的影响
Laura Culicetto,Gabriele Triolo,Roberta Lombardo et al.
Laura Culicetto et al.
Background: Caregiver burden in Parkinson's disease (PD) is influenced by both motor and non-motor symptoms; however, the relative contribution of these domains in late-stage PD remains unclear. This study aimed to examin...
Contextual fear conditioning leads to hypo-innervation of the left ventricular myocardium in female but not male C57BL/6J mice [0.03%]
上下文恐惧条件作用导致C57BL/6J雌小鼠而不是雄小鼠左心室心肌去神经支配不足
Luca M Lautenschläger,Lara Mariel Chirich Barreira,Jonas Labode et al.
Luca M Lautenschläger et al.
Objective: Contextual fear conditioning is an effective way of inducing and modelling anxiety-like states in rodents like mice. We examined the sex-dependent effects of contextual fear conditioning on the autonomic innerv...
High-yawning male rats are more sexually motivated when exposed to sexually receptive female rats in a multichoice sexual paradigm [0.03%]
高伸舌雄性大鼠在多选择性行为实验中对发情雌性大鼠表现出更强的交配动机
Carmen Cortes,Alfonso Mora,Juan M Ibarra-Hernández et al.
Carmen Cortes et al.
During mating, several sensory cues are involved in the sexual interaction process, among which the emission of 50 kHz ultrasonic vocalizations (USVs) plays a key role. We have established two sublines from Sprague-Dawley (SD) rats whose sp...