Katherine S F Damme,Jadyn S Park,Teresa Vargas et al.
Katherine S F Damme et al.
Background: Motor abnormalities, such as psychomotor agitation and retardation, are widely recognized as core features of depression. However, it is not currently known if motor abnormalities connote risk for depression. ...
Secondary Sources of Negative Symptoms in Those Meeting Criteria for a Clinical High-Risk Syndrome [0.03%]
二级精神疾病高危综合征患者的负面症状来源：基于病例对照研究的报告
Tina Gupta,Gregory P Strauss,Henry R Cowan et al.
Tina Gupta et al.
Background: Negative symptoms are diagnostic characteristics of schizophrenia. They can result from primary (i.e., idiopathic) or secondary (i.e., due to other factors such as depression, anxiety, psychosis, disorganizati...
Splenic denervation attenuates repeated social defeat stress-induced T-lymphocyte inflammation [0.03%]
脾神经消减缓解重复性社会挫败应激诱导的T淋巴细胞介导的炎症反应
Safwan K Elkhatib,Cassandra M Moshfegh,Gabrielle F Watson et al.
Safwan K Elkhatib et al.
Background: Post-traumatic stress disorder (PTSD) is a devastating psychological disorder. Patients with PTSD canonically demonstrate an increased risk for inflammatory diseases, as well as increased sympathetic tone and ...
Task-general efficiency of evidence accumulation as a computationally-defined neurocognitive trait: Implications for clinical neuroscience [0.03%]
基于计算定义的神经认知特征的通用效率作为证据积累：对临床神经科学的意义
Alexander Weigard,Chandra Sripada
Alexander Weigard
Quantifying individual differences in higher-order cognitive functions is a foundational area of cognitive science that also has profound implications for research on psychopathology. For the last two decades, the dominant approach in these...
Cannabidiol Produces Distinct U-Shaped Dose-Response Effects on Cocaine-Induced Conditioned Place Preference and Associated Recruitment of Prelimbic Neurons in Male Rats [0.03%]
cannabidiol产生剂量反应U形效应以调节雄性大鼠cocaine诱导的位置偏好及相关地募集前肢皮层神经元
Hermina Nedelescu,Grant E Wagner,Genna L De Ness et al.
Hermina Nedelescu et al.
Background: Cannabidiol (CBD) has received attention for the treatment of substance use disorders. In preclinical models of relapse, CBD attenuates drug seeking across several drugs of abuse, including cocaine. However, i...
Cytokine and Reward Circuitry Relationships in Treatment-Resistant Depression [0.03%]
难治性抑郁患者中细胞因子和奖赏回路的关系
Manivel Rengasamy,Lena Brundin,Angela Griffo et al.
Manivel Rengasamy et al.
Background: Depressive disorders are linked to dysfunction in reward-related behaviors and corticostriatal reward circuitry. Low-grade dysregulation of the immune system, e.g., elevations in plasma interleukin 6 (IL-6) an...
Associations between Brain Structural Alterations, Executive Dysfunction, and General Psychopathology in a Healthy and Cross-Diagnostic Adult Patient Sample [0.03%]
基于健康和跨诊断成年人样本的结构性脑改变、执行功能障碍与一般心理疾病的关联性研究
Adrienne L Romer,Diego A Pizzagalli
Adrienne L Romer
Background: A general psychopathology 'p' factor captures shared variance across mental disorders in diverse samples and may partly reflect executive dysfunction. Higher p factor scores have been related to structural alt...
Systemic Inflammatory Biomarkers in DSM-5-Defined Disorders and COVID-19: Evidence From Published Meta-analyses [0.03%]
基于已发表的meta分析，在DSM-5定义的精神疾病和COVID-19中系统性炎症生物标志物的作用
Angela Duong,Hyunjin Jeong,Dana El Soufi El Sabbagh et al.
Angela Duong et al.
On March 11, 2020, the World Health Organization declared the outbreak of the novel SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) as a global pandemic. At the center of SARS-CoV-2 is the activation of inflammatory markers; re...
Risk of Death in Individuals Hospitalized for COVID-19 With and Without Psychiatric Disorders: An Observational Multicenter Study in France [0.03%]
精神障碍患者和非精神障碍患者的新冠肺炎死亡风险——法国多中心研究的一项观察性研究
Nicolas Hoertel,Marina Sánchez-Rico,Pedro de la Muela et al.
Nicolas Hoertel et al.
Background: Prior research suggests that psychiatric disorders could be linked to increased mortality among patients with COVID-19. However, whether all or specific psychiatric disorders are intrinsic risk factors of deat...