Neighborhood Disadvantage Associated With Blunted Amygdala Reactivity to Predictable and Unpredictable Threat in a Community Sample of Youth [0.03%]
基于社区抽样的儿童青少年样本中,邻里不利与预测性和非预测性威胁的扁桃体反应钝化有关
Ashley A Huggins,Lisa M McTeague,Megan M Davis et al.
Ashley A Huggins et al.
Background: Childhood socioeconomic disadvantage is a form of adversity associated with alterations in critical frontolimbic circuits involved in the pathophysiology of psychiatric disorders. Most work has focused on indi...
Carlos Cardenas-Iniguez,Elisabeth Burnor,Megan M Herting
Carlos Cardenas-Iniguez
While life in urban environments may confer a number of benefits, it may also result in a variety of exposures, with toxic consequences for neurodevelopment and neuropsychological health. Neurotoxicants are any of a large number of chemical...
Neighborhood Socioeconomic Disadvantage and the Neurobiology of Uncertainty in Traumatically Injured Adults [0.03%]
创伤性损伤成年人中的社会经济学劣势与不确定性神经生物学
Carissa W Tomas,E Kate Webb,Kenneth P Bennett et al.
Carissa W Tomas et al.
Background: Individuals residing in more socioeconomically disadvantaged neighborhoods experience greater uncertainty through insecurity of basic needs such as food, employment, and housing, compared with more advantaged ...
Residence in High-Crime Neighborhoods Moderates the Association Between Interleukin 6 and Social and Nonsocial Reward Brain Responses [0.03%]
高犯罪率社区的居住环境会调节细胞因子6与社会和非社会奖励脑区反应之间的关系
Iris Ka-Yi Chat,Andrew A Gepty,Marin Kautz et al.
Iris Ka-Yi Chat et al.
Background: Residence in high-crime neighborhoods, especially in childhood, is linked to mental health issues later. Detecting distinct neurobiological processes underlying the effects of this environmental stressor may b...
Environmental Conditions to Promote Healthy Childhood Brain/Behavioral Development: Informing Early Preventive Interventions for Delivery in Routine Care [0.03%]
促进健康童年脑部和行为发展的环境条件:为常规护理中提供的早期预防干预提供信息
Joan L Luby,Cynthia Rogers,Katie A McLaughlin
Joan L Luby
Environmental experiences early in life have strong and enduring consequences for cognitive, emotional, and neurobiological development and related physical and mental health trajectories. The powerful influence of early caregiver nurturanc...
Oliver Pain,Karen Hodgson,Vassily Trubetskoy et al.
Oliver Pain et al.
Background: Antidepressants are a first-line treatment for depression. However, only a third of individuals experience remission after the first treatment. Common genetic variation, in part, likely regulates antidepressan...
Midcingulate Cortical Activations Interrelate Chronic Craving and Physiological Responses to Negative Emotions in Cocaine Addiction [0.03%]
纹状回激活联结可卡因成瘾者慢性渴求和负面情绪的生理反应
Simon Zhornitsky,Thang M Le,Wuyi Wang et al.
Simon Zhornitsky et al.
Background: Negative emotions precipitate drug craving. Individuals vary in how they engage in negative emotions, as may be reflected in physiological arousal elicited by the emotions. It remains unclear whether physiolog...
Beyond massive univariate tests: Covariance regression reveals complex patterns of functional connectivity related to attention-deficit/hyperactivity disorder, age, sex, and response control [0.03%]
超越大规模单变量检验:协方差回归揭示与注意力缺陷多动障碍、年龄、性别和反应控制相关的功能连接的复杂模式
Yi Zhao,Mary Beth Nebel,Brian S Caffo et al.
Yi Zhao et al.
Background: Studies of brain functional connectivity (FC) typically involve massive univariate tests, performing statistical analysis on each individual connection. In this study we apply a novel whole-matrix regression a...
The Dynamic Relationship Between Alpha and Beta Power and Next-Day Suicidal Ideation in Individuals With Treatment-Resistant Depression [0.03%]
难治性抑郁症患者中 alpha 和 beta 节律与次日自杀意念之间的动态关系
Elizabeth D Ballard,Deanna Greenstein,Wallace C Duncan Jr et al.
Elizabeth D Ballard et al.
Background: Nocturnal wakefulness has emerged as a potential predictor of short-term suicide risk. This analysis used dynamic temporal patterns in alpha and beta power and global sleep metrics to explore the possible link...
A cAMP-Related Gene Network in Microglia Is Inversely Regulated by Morphine Tolerance and Withdrawal [0.03%]
阿片类药物耐受和戒断通过cAMP相关基因网络逆转调节小胶质细胞功能
Kevin R Coffey,Atom J Lesiak,Russell G Marx et al.
Kevin R Coffey et al.
Background: Microglia have recently been implicated in opioid dependence and withdrawal. Mu Opioid (MOR) receptors are expressed in microglia, and microglia form intimate connections with nearby neurons. Accordingly, opio...