Opioid withdrawal produces sex-specific effects on fentanyl-vs.-food choice and mesolimbic transcription [0.03%]
阿片类药物戒断产生性别差异性的芬太尼与食物选择效应及中脑边缘通路转录变化
E Andrew Townsend,R Kijoon Kim,Hannah L Robinson et al.
E Andrew Townsend et al.
Background: Opioid withdrawal is a key driver of opioid addiction and an obstacle to recovery. However, withdrawal effects on opioid reinforcement and mesolimbic neuroadaptation are understudied and the role of sex is lar...
Modeling intrahippocampal effects of anterior hippocampal hyperactivity relevant to schizophrenia using chemogenetic excitation of long axis-projecting mossy cells in the mouse dentate gyrus [0.03%]
利用化学遗传学方法激活小鼠海马齿状回轴索投射的 mossy细胞模拟与精神分裂症相关的腹侧海马高活性及其对海马内的影响
James P Bauer,Sarah L Rader,Max E Joffe et al.
James P Bauer et al.
Background: The anterior hippocampus of individuals with early psychosis or schizophrenia is hyperactive, as is the ventral hippocampus in many rodent models for schizophrenia risk. Mossy cells (MCs) of the ventral dentat...
Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank [0.03%]
利用英国生物银行探究抑郁症和自身免疫疾病之间的多效性关系
Kylie P Glanville,Jonathan R I Coleman,Paul F O&#x;Reilly et al.
Kylie P Glanville et al.
Background: Epidemiological studies report increased comorbidity between depression and autoimmune diseases. The role of shared genetic influences in the observed comorbidity is unclear. We investigated the evidence for p...
Genetic Liability to Cannabis Use Disorder and COVID-19 Hospitalization [0.03%]
cannabis使用障碍的遗传易感性与COVID-19住院风险之间的关联研究
Alexander S Hatoum,Claire L Morrison,Sarah M C Colbert et al.
Alexander S Hatoum et al.
Background: Vulnerability to COVID-19 hospitalization has been linked to behavioral risk factors, including combustible psychoactive substance use (e.g., tobacco smoking). Paralleling the COVID-19 pandemic crisis have bee...