Stress History Modulates Corticotropin-Releasing Factor Neurons to Establish Resilience [0.03%]
应激史通过调节促肾上腺皮质激素释放因子神经元来建立心理韧性
Sherod E Haynes,Anthony Lacagnina,Hyun Seong Seo et al.
Sherod E Haynes et al.
Background: Cumulative stress is a major risk factor for developing major depressive disorder (MDD), but not everyone experiencing chronic stress develops MDD. In those who do not, it is unclear at what point or by what m...
Considerations for Neural Cannabis Cue-Reactivity Studies in Individuals With Cannabis Use Disorder [0.03%]
大麻使用障碍个体中神经元大麻线索诱发性研究的考量因素
Erica N Grodin,Kaitlin McManus
Erica N Grodin
Increased Tumor Necrosis Factor Superfamily Members in Neuroinflammatory Schizophrenia and Bipolar Disorder Midbrains [0.03%]
神经炎症性精神分裂症和双相情感障碍脑桥延髓中肿瘤坏死因子超家族成员的增加
Gerardo Mendez-Victoriano,Yunting Zhu,Layla Neuhaus et al.
Gerardo Mendez-Victoriano et al.
Background: Neuroinflammation is a key neuropathological finding in schizophrenia and bipolar disorder, as increased cytokines are found in the midbrain of these individuals. However, the most upregulated inflammatory cyt...
Causal Effects of Enhanced Parenting on Resting-State Graph Properties of Adolescents at Risk for Maltreatment [0.03%]
强化养育对 maltreatment 高危青少年静息态脑功能连接的影响研究
Marta Korom,Mary Dozier,Hung-Wei Bernie Chen et al.
Marta Korom et al.
Background: In this study, we investigated the sustained causal effects of enhanced early caregiving quality on adolescent brain network properties approximately 11 years after families received an attachment-based parent...
Glucagon-Like Peptide-1 Receptor Agonists and Alcohol Use: A Real-Word Observational Study in a Large, Integrated Health Care System [0.03%]
胰高血糖素样肽-1受体激动剂和饮酒行为：一项大型综合医疗体系中的真实世界观察研究
Vanessa A Palzes,Brianna Costales,Stacy Sterling et al.
Vanessa A Palzes et al.
Background: Growing research suggests that glucagon-like peptide-1 receptor agonists (GLP-1RAs) reduce alcohol consumption, positioning them as new potential pharmacotherapies for alcohol use disorder. However, human stud...
Mineralocorticoid Receptor in Glutamatergic Neurons Modulates Anxiety Exclusively in Male Mice Via Regulation of the Actin-Bundling Factor Fam107a [0.03%]
谷氨酸能神经元中的矿物质受体通过调节肌动蛋白束状因子Fam107a的方式在雄性小鼠中选择性地调节焦虑反应
Huanqing Yang,Sowmya Narayan,Joeri Bordes et al.
Huanqing Yang et al.
Background: Exposure to stressful life events is a major risk factor for many psychiatric disorders. The mineralocorticoid receptor (MR) is a key regulator of the hypothalamic-pituitary-adrenal axis, a central stress resp...