Temporal Dynamics of Reward Dysfunction in Psychiatric Disorders: Memory-Derived Value, Incentive Salience, Hedonic Impact, and Value Updating [0.03%]
精神疾病中奖励功能障碍的时空动态：记忆衍生价值、激励意义、快感和价值更新
Feng Zou,Xiaochen Yang,Congcong Liu et al.
Feng Zou et al.
Reward processing unfolds across time: Prior experiences shape cue valuation and motivation, anticipated rewards bias action selection, reward encounters generate hedonic and evaluative signals, and outcomes update future value representati...
Fatigue Symptoms Influence Effort-Based Decision-Making in Major Depressive Disorder [0.03%]
疲劳症状对抑郁症患者的基于努力决策的影响
Grace E Steward,Adam J Culbreth,Fernando S Goes et al.
Grace E Steward et al.
Background: Fatigue is a central symptom of major depressive disorder (MDD). Studies in healthy individuals suggest that fatigue reduces willingness to exert effort, but its role in effort-based decision making in MDD rem...
Prazosin-Related Reductions in Daily Craving Mediate Treatment-Related Daily Alcohol Use Outcomes in Alcohol Use Disorder [0.03%]
氯丙嗪相关的日常渴求减少可以改善酒精使用障碍者的日常饮酒行为
Stephanie Wemm,Rachel Hart,Gretchen Hermes et al.
Stephanie Wemm et al.
Background: Prazosin has been shown to reduce drinking, particularly in individuals with alcohol withdrawal symptoms, possibly due to reducing craving as shown in experimental studies. However, it is unclear whether prazo...
Effects of Schizophrenia, Bipolar Disorder, and Depression on Cardiopulmonary and Abdominal Organ Structure [0.03%]
精神分裂症、双相情感障碍和抑郁对心肺及腹部器官结构的影响
Shengsi Chu,Francesco Casanova,Renu Bala et al.
Shengsi Chu et al.
Background: People with severe mental illness (SMI) have shorter life expectancy, largely driven by physical health conditions. While lifestyle and psychotropic side effects contribute, peripheral organ dysregulation is i...
APOE Genotypes Modulate the Relationship of Hypertension With Alzheimer's Disease: Associations and Clues of Peripheral Mechanisms [0.03%]
载脂蛋白E基因多态性通过调节高血压与阿尔茨海默病的关系影响发病风险：来自横断面和前瞻性队列研究的证据及关于外周机制的启示
Hong-Yu Wu,Jia-Hui Hou,Liang-Yu Huang et al.
Hong-Yu Wu et al.
Background: Gene-environment interplay contributes to the heterogeneous etiology of Alzheimer's disease (AD). Hypertension (HTN) is a major modifiable vascular risk factor, but whether its association with AD differs acro...
Prospective Development of a Whole-Brain Connectivity and Electric Field-Guided Transcranial Magnetic Stimulation Atlas for Posttraumatic Stress Disorder Symptoms [0.03%]
前瞻性开发用于创伤后应激障碍症状的全脑连接和电场引导经颅磁刺激图集
Sneha Chandrashekar,Grant Brighter,Ivy Sun et al.
Sneha Chandrashekar et al.
Background: Although trauma-focused psychotherapy remains the first-line treatment for posttraumatic stress disorder (PTSD), 14% to 35% of individuals with PTSD fail to achieve symptom remission. Transcranial magnetic sti...
Dynamic Repertoire of Brain Networks in Mindfulness-Based Cognitive Therapy During Rumination: A Randomized Controlled Trial [0.03%]
正念认知疗法中思维反刍时的大脑网络动态变化：一项随机对照试验
Anne Maj van der Velden,Jakub Vohryzek,Paulina Clara Dagnino et al.
Anne Maj van der Velden et al.
Background: Depression is a prevalent and debilitating affective disorder characterized by the dominance and persistence of depressive rumination. Mindfulness-based cognitive therapy (MBCT) is an effective treatment for r...
Perceived Social Support Moderates the Response to Stress and Alcohol Cues During Early Abstinence From Alcohol [0.03%]
感知到的社会支持缓和了戒酒初期个体对压力及酒精暗示的反应程度
Samantha J Goldstein,Rajita Sinha,Helen C Fox
Samantha J Goldstein
Background: Alcohol addiction is associated with maladaptive stress responses that heighten craving and relapse risk during early abstinence. While perceived social support (PSS) is theorized to act as a stress buffer, it...
Developmental Brain Network Trajectories Differentiate Resilience and Vulnerability to Psychosis in 22q11.2 Deletion Syndrome [0.03%]
22q11.2微缺失综合征患者 resilience和易患精神病的脑网络发育轨迹不同
Silas Forrer,Farnaz Delavari,Corrado Sandini et al.
Silas Forrer et al.
Background: Disrupted maturation of functional brain networks has been increasingly linked to elevated risk of psychosis, but the spatiotemporal characteristics of these deviations remain unclear. We used longitudinal con...
Neurophysiological Correlates of Neuroanatomical Dimensions in Major Depressive Disorder: Electroencephalographic Markers of Brain Function and Treatment Outcome [0.03%]
抑郁症的神经解剖维度的神经生理相关性：脑功能和治疗效果的脑电标志物
Wenyi Xiao,Rachel D Woodham,Mathilde Antoniades et al.
Wenyi Xiao et al.
Background: Major depressive disorder (MDD) is heterogeneous in clinical presentation and treatment response. The COORDINATE-MDD consortium identified two magnetic resonance imaging (MRI)-derived neuroanatomical profiles:...