Transforming monosaccharides: Recent advances in rare sugar production and future exploration [0.03%]
单糖的转化：稀少糖生产的新进展和未来探索
Shin-Ichi Nakakita,Jun Hirabayashi
Shin-Ichi Nakakita
Rare sugars are defined as monosaccharides and their derivatives that do not exist in nature at all or that exist in extremely limited amounts despite being theoretically possible. At present, no comprehensive dogma has been presented regar...
Alba Hykollari,Daniel Malzl,Chunsheng Jin et al.
Alba Hykollari et al.
Dictyostelia are cellular slime molds, a group of Amoebozoa, that form multicellular fruiting bodies out of aggregating cells able of differentiating into resistant spore forms. In previous studies on Dictyostelium discoideum, it was demons...
Extracellular vesicles display distinct glycosignatures in high-grade serous ovarian carcinoma [0.03%]
高级别浆液性卵巢癌的细胞外囊泡具有不同的糖基化标志物
Kristina Mae Bienes,Akira Yokoi,Masami Kitagawa et al.
Kristina Mae Bienes et al.
High-grade serous ovarian carcinoma (HGSOC) is a deadly subtype of ovarian cancer (OC), often diagnosed at late stages due to nonspecific symptoms and lack of effective markers for early detection. Aberrant protein N-linked glycosylation ha...
Chengcheng Huang,Akinobu Honda,Tadashi Suzuki
Chengcheng Huang
Glycans are sugars/sugar chains that are usually linked to proteins or lipids. The attachment of glycans often results in alterations of physicochemical/physiological properties of the carrier molecules, e.g., glycosylation of proteins can ...
Effect of halo-tolerance gene Hal5 on ethanol tolerance of Saccharomyces cerevisiae [0.03%]
耐盐基因Hal5对酿酒酵母耐乙醇性的影响研究
L Singh,J Rai,S C Sharma
L Singh
Hal5 gene is involved in halo-tolerance of Saccharomyces cerevisiae during high salt stress. Ethanol stress and high salt stress have similarities, as both decrease the availability of water for cells and strain the osmotic homeostasis acro...
Impact of different pathogen classes on the serum N-glycome in septic shock [0.03%]
不同病原菌对脓毒性休克患者血清N-连接聚糖谱的影响研究
Helena Torpy,The Huong Chau,Sayantani Chatterjee et al.
Helena Torpy et al.
The morbidity and mortality of sepsis remain high. Clinicians lack effective markers to rapidly diagnose sepsis and identify the underlying pathogen infection particularly for patients with candidaemia or cases of culture-negative sepsis wh...
Total cell N-glycosylation is altered during differentiation of induced pluripotent stem cells to neural stem cells and is disturbed by trisomy 21 [0.03%]
诱导多能干细胞向神经干细胞分化过程中总细胞N-糖基化发生变化，并且21三体导致此过程异常
Ana Cindrić,Frano Vučković,Aoife Murray et al.
Ana Cindrić et al.
Down syndrome (DS), a genetic condition caused by trisomy 21 (T21), manifests various neurological symptoms, including intellectual disability, early neurodegeneration, and early-onset dementia. N-glycosylation is a protein modification tha...
Loss or inhibition of lysosomal acid lipase in vitro leads to cholesteryl ester accumulation without affecting muscle formation or mitochondrial function [0.03%]
体外溶酶体酸性脂肪酶丧失或受抑制导致胆固醇酯堆积而不影响肌生成或线粒体功能
Alena Akhmetshina,Laszlo Schooltink,Melina Amor et al.
Alena Akhmetshina et al.
Skeletal muscle (SM) is essential for movement, stability, and overall body function, and it readily adapts to changes in energy demand. Myogenesis is energy-intensive and involves complex molecular and cellular events. We recently demonstr...
Capturing the micro-communities: Insights into biogenesis and architecture of bacterial biofilms [0.03%]
捕捉微小社区：细菌生物膜的发生学和结构的启示
Harshita Agarwal,Bharat Gurnani,Bhumika Pippal et al.
Harshita Agarwal et al.
Biofilm is an assemblage of microorganisms embedded within the extracellular matrix that provides mechanical stability, nutrient absorption, antimicrobial resistance, cell-cell interactions, and defence against host immune system. Various b...
Phosphorylation of N-glycans in the brain: The case for a non-canonical pathway? [0.03%]
脑中的N-聚糖的磷酸化：非经典通路的案例？
Lucija Sironić,Nikol Mraz,Gordan Lauc et al.
Lucija Sironić et al.
Asparagine-linked glycosylation (N-glycosylation) is a common co- and post-translational modification that refers to the addition of complex carbohydrates, called N-linked glycans (N-glycans), to asparagine residues within defined sequons o...