Evolution and function of galectins in Xenopus laevis: Comparison with mammals and new perspectives [0.03%]
非洲爪蟾半乳糖凝集素的进化与功能及其与哺乳动物的比较和新的研究视角
Takashi Ogawa,Yasuhiro Nonaka,Hiroki Shoji et al.
Takashi Ogawa et al.
Galectins are metal-independent sugar-binding proteins that recognize galactose (the β-galactoside structure) and regulate the cross-linking of sugar chains between cells and the extracellular matrix. Their specificity for galactose is att...
Current issues of tandem mass spectrum (MS2)-based glycoproteomics and efforts to complement them [0.03%]
基于串联质谱的糖蛋白质组学当前问题及补充分析的努力
Hiroyuki Kaji
Hiroyuki Kaji
With the development of liquid chromatography/mass spectrometers that support proteomics and the associated development of analytical methods and data analysis software, the number of proteins that can be identified and quantified in a sing...
Characterization of HOL-30: a novel tandem-repeat galectin from the marine sponge Halichondria okadai [0.03%]
HOL-30的特征研究：来源于海洋海绵Okada's halichondria的新颖串联重复半乳糖凝集素
Mayuka Ohkawa,Kenichi Kamata,Sarkar M A Kawsar et al.
Mayuka Ohkawa et al.
We here report the novel primary structure of a new member in the galectin family, the β-galactoside-binding lectin HOL-30, from the marine sponge Halichondria okadai, whose full-length sequence was determined thanks to the combination bet...
Clara Dessenne,Christophe Mariller,Olivier Vidal et al.
Clara Dessenne et al.
Bacterial adhesins play a central role in host-pathogen interactions, with many specifically targeting glycans to mediate bacterial colonization, influence infection dynamics, and evade host immune responses. In this review, we focus on bac...
Frédérique Lisacek,Boris Schnider,Anne Imberty
Frédérique Lisacek
Lectins are ubiquitous proteins that interact with glycans in a variety of molecular processes and as such, also play a role in diseases, whether infectious, chronic or cancer-related. The systematic study of lectins is therefore essential,...
Development of a permethylation-based detection method for oligo/polysialic acid structures via tandem MALDI-TOF mass spectrometry [0.03%]
基于串聯MALDI-TOF質譜的寡/聚唾液酸結構的全甲基化檢測方法的建立
Kai Suzuki,Di Wu,Ken Kitajima et al.
Kai Suzuki et al.
Oligo/polysialic acid (oligo/polySia) refers to a class of linear polymers composed of Sias, found extensively at the non-reducing ends of glycans across various organisms, from bacteria to vertebrates. Different types of oligo/polySia have...
Advances in total glycomic analysis including sialylated sub-glycan isomers by SALSA method [0.03%]
SALSA方法在总糖谱分析（包括唾液酸化子低聚糖异构体）中的进展
Masaki Kurogochi,Chiharu Suzuki,Hisatoshi Hanamatsu et al.
Masaki Kurogochi et al.
All eukaryotic cell surfaces are coated with various types of glycans, which are essential molecules in biological events. In this review, we summarize recent integrated glycomics studies using various biological samples. We introduce an im...
Quality assessment strategy development and analytical method selection of GMP grade biological drugs for gene and cell therapy [0.03%]
基因和细胞治疗GMP级生物药物的质量评估策略发展及分析方法选择
Quan-En Yang,Nicole Lee,Nicole Johnson et al.
Quan-En Yang et al.
Biological drugs with gene and cell therapy potentials, including natural or rationally created biomacromolecules, recombinant proteins/enzymes, gene-carrying DNA/RNA fragments, oncolytic viruses, plasmid and viral vectors or other gene del...
Plant acetyl-CoA carboxylase: The homomeric form and the heteromeric form [0.03%]
植物乙酰辅酶A羧化酶：同型形式和异型形式
Dilawar Niazi,Greg B G Moorhead
Dilawar Niazi
Across the domains of life, the enzyme acetyl-CoA carboxylase (ACC) converts HCO3 -, ATP, and acetyl-CoA to malonyl-CoA, ADP, and Pi. Malonyl-CoA is the building block for all de novo fatty acid biosynthesis. ACC is found in two forms, (1) ...
Ryne Montoya,Peter Deckerman,Mustafa O Guler
Ryne Montoya
The fundamental biological processes involving highly specific interactions between proteins and other biological motifs are the pillars of protein recognition mechanisms. These interactions are crucial for biological systems, often having ...