Sex-based estimation of biological variation in plasma-free amino acid concentrations among healthy adults [0.03%]
健康成人血浆游离氨基酸浓度的性别差异及生物学变异估算
Müjgan Ercan,Emiş Deniz Akbulut,Ayşen Caniklioğlu et al.
Müjgan Ercan et al.
Introduction: Free amino acid (FAA) analysis plays a crucial role in diagnosing and monitoring inborn errors of metabolism, assessing nutritional status, and identifying metabolic imbalances associated with various diseas...
Validation of an LC-MS/MS method for urinary homovanillic and vanillylmandelic ACIDS and application to the diagnosis of neuroblastoma [0.03%]
尿液高香草酸和香草基马ント酸的LC-MS/MS测定法验证及在神经母细胞瘤诊断中的应用
Lucilla Rossi,Yvette A H Matser,Sebastiano Barco et al.
Lucilla Rossi et al.
Background: Urinary catecholamine metabolites are well-established biomarkers for neuroblastoma (NB). Homovanillic acid (HVA) and vanillylmandelic acid (VMA) are the most frequently measured metabolites within SIOPEN - Ca...
Quantification of glucagon and oxyntomodulin by protein precipitation-immunoaffinity enrichment-LC-MS/MS [0.03%]
基于蛋白质沉淀-免疫亲和萃取的LC-MS/MS法同时定量检测胰高血糖素和oxyntomodulin肽激素
Jessica O Becker,Sara K Shijo,Huu-Hien Huynh et al.
Jessica O Becker et al.
Introduction: Glucagon and oxyntomodulin are peptide hormones differentially released from proglucagon that function in regulating blood glucose. Their overlapping amino acid sequences make the development of specific imm...
A rapid method for determination of rosuvastatin in blood plasma with supported liquid extraction [0.03%]
一种使用支持液提取法测定血浆中罗苏伐他汀的快速方法
Tjaša Dermota,Mojca Božič Mijovski,Jurij Trontelj
Tjaša Dermota
Introduction: Accurate measurement of rosuvastatin in plasma is critical for effective patient management and treatment monitoring following myocardial infarction (MI). Expensive solid-phase extraction (SPE) and time-cons...
Development and validation of a highly-sensitive, quantitative LC-MS/MS assay to evaluate plasma oxytocin [0.03%]
高灵敏度定量液质联用法的建立及验证用于评估血浆中的催产素含量
E Grifnée,A Mackowiak,J Demeuse et al.
E Grifnée et al.
Introduction: Oxytocin is a 9-amino acid peptide that serves as neuromodulator in the human central nervous system. This peptide is implicated in the regulation of diverse behaviors and plays a significant role in positiv...
A multiplex assay of leptin, resistin, and adiponectin by immunoaffinity enrichment and targeted mass spectrometry [0.03%]
通过免疫亲和富集和靶向质谱多重检测瘦素、抵抗素和脂联素
Jie Pu,Xinxin Yang,Tai-Tu Lin et al.
Jie Pu et al.
Background: Leptin, resistin, and adiponectin are critical adipokines involved in the pathophysiology of obesity and its related disorders, including type 2 diabetes. Although these biomarkers have historically been quant...
Barcoded labels as potential source of zinc contamination in trace metal testing [0.03%]
条形码标签可能是痕量金属检测中锌污染的潜在来源
Difei Sun,Donna Sealy,Dorothy Truong et al.
Difei Sun et al.
Will Grothoff,Ivan Khodakivskyi,Aleks Shin et al.
Will Grothoff et al.
Introduction: C-peptide secretion mirrors beta-cell function and has emerged as a valuable clinical biomarker for diabetes mellitus. C-peptide measurements can provide estimates of insulin secretory capacity, aiding in cl...
High-resolution mass spectrometry measurement of N-terminal carbamylated hemoglobin as a potential marker for chronic diseases with elevated blood urea levels [0.03%]
高分辨率质谱法测定血红蛋白的氨基末端羰基化衍生物作为慢性疾病的潜在标志物
Fangjun Chen,Priscilla S-W Yeung,Carolyn V Wong et al.
Fangjun Chen et al.
Introduction: N-terminal carbamylated hemoglobin (CarHb) reflects long-term blood urea levels and has potential as a marker for chronic kidney disease (CKD) and other chronic conditions with elevated blood urea levels. A ...
A liquid chromatography-high-resolution mass spectrometry method for separation and identification of hemoglobin variant subunits with mass shifts less than 1 Da [0.03%]
用于分离和识别质量偏移小于1道尔顿的血红蛋白变异亚基的液相色谱高分辨率质谱方法
Ainslie Chen,Ryan M Aquino,Hector A Vidal et al.
Ainslie Chen et al.
Background: Identification of hemoglobin (Hb) variants is valuable in clinical testing. A common issue with conventional methods for identifying Hb variants is their subpar ability to provide structural breakdowns of the ...