Characteristics of peripheral blood cells are independently related to major adverse cardiovascular events after carotid endarterectomy [0.03%]
颈动脉内膜剥脱术后外周血细胞特征与主要心血管不良事件的独立关系分析
L Malin Overmars,Joost M Mekke,Wouter W van Solinge et al.
L Malin Overmars et al.
Background and aims: Patients who underwent carotid endarterectomy (CEA) still have a residual risk of 13% of developing a major adverse cardiovascular event (MACE) within 3 years. Inflammatory processes leading up to MAC...
SARS-CoV-2 reinfection: Adding insult to dysfunctional endothelium in patients with atherosclerotic cardiovascular disease [0.03%]
新冠病毒再感染：在动脉粥样硬化性心血管病患者中对功能失调的内皮细胞造成进一步损害
Petri T Kovanen,Alpo Vuorio
Petri T Kovanen
In this short narrative review, we aim at defining the pathophysiological role endothelial dysfunction in the observed COVID-19-associated rise in risk of cardiovascular disease. Variants of the SARS-CoV-2 virus have caused several epidemic...
Fibronectin extra domain a limits liver dysfunction and protects mice during acute inflammation [0.03%]
纤维连接蛋白额外区段A限制肝功能障碍并在急性炎症期间保护小鼠
Vivek Krishna Pulakazhi Venu,Annalisa Moregola,Lorenzo Da Dalt et al.
Vivek Krishna Pulakazhi Venu et al.
Background and aim: The primary transcript of fibronectin (FN) undergoes alternative splicing to generate different isoforms, including FN containing the Extra Domain A (FN_EDA+), whose expression is regulated spatially a...
David Leibowitz,Yuriko Yoshida,Zhezhen Jin et al.
David Leibowitz et al.
Background and aims: The presence of aortic arch plaques (AAP) is significantly associated with increased cardiovascular morbidity and mortality. Few studies have examined the incidence of AAP progression and factors whic...
Chiara Pavanello,Alice Ossoli
Chiara Pavanello
Low HDL-cholesterol (HDL-C) concentrations are a typical trait of the dyslipidemia associated with chronic kidney disease (CKD). In this condition, plasma HDLs are characterized by alterations in structure and function, and these particles ...
Associations of urinary isoprostanes with measures of subclinical atherosclerosis: The Multi-Ethnic Study of Atherosclerosis (MESA) [0.03%]
尿液异前列酮与亚临床动脉粥样硬化的测量指标的关系：多元民族动脉粥样硬化研究（MESA）中的发现
Ryan L Wallace,Oluseye Ogunmoroti,Di Zhao et al.
Ryan L Wallace et al.
Background: Urinary isoprostanes are markers of systemic oxidative stress, which is implicated in the pathogenesis of atherosclerotic cardiovascular disease (ASCVD). Coronary artery calcium (CAC), thoracic aortic calcium ...
Johan Skov Bundgaard,Marit E Jørgensen,Kristine Andersen et al.
Johan Skov Bundgaard et al.
Background: Low-density lipoprotein cholesterol (LDL-C) is a well-established risk factor for development of cardiovascular diseases. Based on available clinical data, we aimed to investigate the plasma lipid profile in t...
Dendritic cell marker Clec4a4 deficiency limits atherosclerosis progression [0.03%]
树突状细胞标志物Clec4a4缺乏限制动脉粥样硬化的发展进展
Rossella Bellini,Annalisa Moregola,Jasmine Nour et al.
Rossella Bellini et al.
Background and aims: Atherogenesis results from altered lipid metabolism and impaired immune response. Emerging evidence has suggested that dendritic cells (DCs) participate to atherosclerosis-related immune response, but...
Lp(a) does not affect intima media thickness in hypercholesterolemic children -a retrospective cross sectional study [0.03%]
Lp(a)不会影响高胆固醇儿童的内膜中层厚度-一项回顾性横断面研究
Oliver Helk,Andreas Böck,Claudia Stefanutti et al.
Oliver Helk et al.
Purpose: Combined hyperlipidaemia results in premature atherosclerosis and a high burden of cardiovascular morbidity and mortality. Early identification of highly affected subjects within this population is of utmost impo...
Young women with familial hypercholesterolemia have higher LDL-cholesterol burden than men: Novel data using repeated measurements during 12-years follow-up [0.03%]
家族性高胆固醇血症的年轻女性低密度脂蛋白胆固醉负担高于男性：基于12年随访数据的新发现
Anja K Johansen,Martin P Bogsrud,Jacob J Christensen et al.
Anja K Johansen et al.
Background and aims: The concentration and the duration of exposure to low-density lipoprotein cholesterol (LDL-C) (LDL-C burden) is an important determinant of risk for cardiovascular disease and thresholds has recently ...