Impact of NAFLD-related SNPs on the carotid atherosclerosis development; a five-year prospective observational study [0.03%]
非酒精性脂肪肝相关遗传位点对颈动脉粥样硬化发生发展影响的前瞻性研究
Hiroaki Ikezaki,Ryoko Nakashima,Yuji Matsumoto et al.
Hiroaki Ikezaki et al.
Background and aims: The prevalence of metabolic dysfunction associated steatotic liver disease (MASLD), formerly known as nonalcoholic fatty liver disease (NAFLD), has become a significant public health concern with an i...
Nicola Ferri,Giorgia Marodin
Nicola Ferri
Pharmacological inhibition of Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) have been firmly established to be an effective approach to reduce low-density lipoprotein (LDL) cholesterol levels and cardiovascular events. Subcutaneous admin...
A cross-tissue transcriptome-wide association study identifies WDPCP as a potential susceptibility gene for coronary atherosclerosis [0.03%]
横断面转录组关联研究确定WDPCP是冠状动脉粥样硬化的潜在易感基因
Xinyue Hu,Guanglei Chen,Xiaofang Yang et al.
Xinyue Hu et al.
Background: Coronary atherosclerosis (CAS) is a complex chronic inflammatory disease with significant genetic and environmental contributions. While genome-wide association studies (GWAS) have pinpointed many risk loci, o...
Real-world data lipid profiles in one million colombian adults: The LiPAC million person study [0.03%]
一百万哥伦比亚成年人的现实世界血脂谱特征——LiPAC百万研究项目
Claudia C Colmenares-Mejía,Marcela Godoy-Corredor,Esteban Morales-Mendoza et al.
Claudia C Colmenares-Mejía et al.
Background and aims: Lipid profile results are of clinical interest for assessing the presence of dyslipidemia and the risk of cardiovascular disease. This study aimed to characterize lipid profile parameters in a large a...
A collaborative effort across Africa to investigate risk factors and outcomes of premature acute coronary syndrome: Protocol for the EAS Lipid Registry of Africa (LIPRA) [0.03%]
非洲早期急性冠脉综合征风险因素及预后的大规模合作研究项目——非洲动脉硬化学会血脂登记注册（LIPRA）项目方案
Ashraf Reda,Alexander R M Lyons,Alberto Zambon et al.
Ashraf Reda et al.
Data on acute coronary syndrome (ACS) is lacking in Africa where cases of premature ACS seem to be on the rise. Africa would benefit from an epidemiological assessment of premature ACS to determine its risk factors and management in this de...
Adherence to the Healthy Nordic Food Index is associated with reduced plasma levels of inflammatory markers in patients with heterozygous familial hypercholesterolemia [0.03%]
健康北欧饮食指数依从性与杂合子家族高胆固醇血症患者炎症标志物的血浆水平降低相关
Eirin B Løvheim,Kjetil Retterstøl,Ingunn Narverud et al.
Eirin B Løvheim et al.
Background and aims: Familial hypercholesterolemia (FH) is an inherited disease associated with hypercholesterolemia, and dietary treatment is part of the treatment. We aimed to assess the dietary pattern in relation to t...
Efficacy and safety of lipid-lowering therapies in combination with or without statin to reduce the cardiovascular risk: A systematic review of randomised controlled trials [0.03%]
非他汀类降脂疗法与他汀类药物联合或单药治疗降低心血管风险的有效性和安全性：系统评价和 meta 分析
Gabriella Iannuzzo,Geetank Kamboj,Parinita Barman et al.
Gabriella Iannuzzo et al.
Background and aims: Cardiovascular diseases (CVD) pose a significant global health burden. Lowering low-density lipoprotein-cholesterol is the primary therapeutic aim for preventing primary and secondary CVD events. Whil...
Lipoprotein(a) and the atherosclerotic burden - Should we wait for clinical trial evidence before taking action? [0.03%]
脂蛋白(a)与动脉粥样硬化负担-临床试验证据之前是否应立即采取行动？
Isabella Fichtner,Chiara Macchi,Alessandra Stefania Rizzuto et al.
Isabella Fichtner et al.
The fact that lipoprotein(a) levels should be regarded as a causal residual risk factor in the atherosclerotic cardiovascular diseases (ASCVD) is now a no-brainer. This review article aims to summarize the latest evidence supporting the cau...
Coronary artery calcification score and 19 biomarkers on cardiovascular events; a 10-year follow-up DanRisk substudy [0.03%]
冠状动脉钙化评分与19种生物标志物对心血管事件的影响；DanRisk的10年随访子研究
Mie Schæffer,Jeppe Holm Rasmussen,Maise Høigaard Fredgart et al.
Mie Schæffer et al.
Aim: The SCORE2 algorithm is recommended to estimate risk of cardiovascular disease (CVD). Coronary artery calcification (CAC) score is expensive but improves the risk prediction. This study aims to determine and compare ...
Eligibility for marine omega-3 fatty acid supplementation after acute coronary syndromes [0.03%]
急性冠脉综合征后海洋ω-3脂肪酸补充剂的使用指征
Cédric Follonier,Gabriel Rabassa,Mattia Branca et al.
Cédric Follonier et al.
Background and aims: The 2019 European Society of Cardiology guidelines for the management of dyslipidemia consider the use of high-dose marine omega-3 fatty acid (FA) eicosapentaenoic acid (EPA) supplementation (icosapen...