Emerging cytokines contribute to the clinical manifestation of carotid artery plaque formation and stability in patients with diabetes [0.03%]
新兴细胞因子参与糖尿病患者颈动脉斑块形成及稳定性临床表现
Zhongqing Xu,James Healy,Wenhui Dong et al.
Zhongqing Xu et al.
Background: Type 2 diabetes mellitus (T2DM) promotes atherosclerosis and plaque instability through chronic inflammation and immune dysregulation. Emerging evidence implicates members of the interleukin-1 family-particula...
Lipidome of high-density lipoprotein is strongly perturbed in hyperalphalipoproteinemia resulting from a rare mutation in endothelial lipase [0.03%]
罕见内皮脂肪酶突变引起的高α-脂蛋白血症患者高密度脂蛋白脂质组分严重紊乱
Livia Pisciotta,Marie Lhomme,Chiara Pavanello et al.
Livia Pisciotta et al.
Both low and extremely high concentrations of high-density lipoprotein (HDL)-cholesterol are associated with elevated cardiovascular risk. As extremely high HDL-cholesterol states of hyperalphalipoproteinemia (HALP) are rare, HDL particles ...
Lp(a) in daily clinical routine: risk-factor for both cardiovascular events and heart-failure? A retrospective analysis of the Luebeck Lp(a) heart-failure (HF) registry in patients after myocardial infarction [0.03%]
Lp(a)在日常临床常规中的作用:心血管事件和心力衰竭的风险因素?对心肌梗死后患者的吕贝克Lp(a)心力衰竭(HF)登记处进行的回顾性分析
Matthias Mezger,Tilmann Solle,Dominik Jurczyk et al.
Matthias Mezger et al.
Background and aims: Atherosclerotic cardiovascular disease (ASCVD) is a major health burden being the leading cause of death in Europe. Lipoprotein (a) (Lp(a)) is an important risk factor for CV events reflected by the 2...
Comparative 10-year atherosclerotic cardiovascular disease risk in Ethiopian HIV patients on first-line versus second-line combined antiretroviral therapy [0.03%]
接受一线与二线抗逆转录病毒治疗的埃塞俄比亚HIV患者十年动脉粥样硬化性心血管疾病风险比较研究
Balew Arega,Gashaw Solela,Tariku Fekadu et al.
Balew Arega et al.
Background: Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of morbidity and mortality in HIV patients, but the impact of combined antiretroviral therapy regimens on its risk in Ethiopia is unclear. This...
Proposed lipidology and preventive cardiology research priorities in Africa; Results of a Delphi survey [0.03%]
非洲脂质学和预防心脏病学研究优先事项的德尔菲调查结果
Alexander R M Lyons,Frederick J Raal,Brett S Mansfield et al.
Alexander R M Lyons et al.
Despite a population of over 1.5 billion, lipidology and preventive cardiology research of African origin is lacking in quantity and impact, and accounts for a small percentage of outputs globally due to limited resources to address the ful...
Association of uric acid with all-cause mortality in acute coronary syndrome patients with T2DM [0.03%]
尿酸与2型糖尿病急性冠脉综合征患者全因死亡率的关系
Bing-Yang Zhou,Jian-Jun Yan,Cui-Ying Zhang et al.
Bing-Yang Zhou et al.
Background: The specific prognostic value of hyperuricemia for all-cause mortality in patients with concurrent type 2 diabetes mellitus (T2DM) and acute coronary syndrome (ACS) remains unclear, particularly regarding the ...
The role and mechanism of PGC-1α in oxLDL-induced ferroptosis of vascular endothelial cells [0.03%]
PGC-1α在氧化型低密度脂蛋白诱导的血管内皮细胞铁死亡中的作用及机制研究
Jiao Li,Pingping He,Yu Zhang et al.
Jiao Li et al.
Ferroptosis is a regulated form of cell death that is dependent on reactive oxygen species (ROS) and iron metabolism. Ferroptosis can participate in the formation and rupture of atherosclerotic plaque by regulating apoptosis. However, the m...
Fucosterol exerts an anti-atherosclerotic action via NF-κB and p38/Erk MAPK signaling pathways [0.03%]
茯苓sterol通过NF-κB和p38/Erk MAPK信号途径发挥抗动脉粥样硬化作用
Tiancheng Liu,Mengli Zhang,Xian Wu et al.
Tiancheng Liu et al.
Background: Fucosterol is a sterol isolated from brown algae and has various biological properties, such anti-inflammatory and antidiabetic effects. In this study, we investigated the anti-atherosclerosis effects of fucos...
Association of dietary preferences with cardiovascular disease: a Mendelian randomization study [0.03%]
饮食偏爱与心血管疾病的关系:一项孟德尔随机化研究
Mia D Lee,Benjamin F Voight
Mia D Lee
Background and aims: Susceptibility to cardiovascular disease (CVD) is driven by genetic and environmental risk factors. Diet is a modifiable and largely environmental risk factor for CVD. Genetic factors associated with ...
Plasma apolipoprotein concentrations and occurrence of cardiovascular events in the general population: an exploratory analysis [0.03%]
人群血浆载脂蛋白浓度与心血管事件的关联:一项探索性分析
Avedis Torossian,Annelise Genoux,Zichun Cai et al.
Avedis Torossian et al.
Background and aims: The role of many apolipoproteins in cardiovascular disease (CVD) pathophysiology and their predictive potential remains unclear. This study examined the association between plasma concentrations of a ...