Circular RNA expression profile of H2O2 induced ferroptosis model of human coronary artery endothelial cells [0.03%]
H₂O₂诱导的人冠状动脉内皮细胞铁死亡模型中的环状RNA表达谱分析
Can Hou,Yong Wang,Yanjun Wang et al.
Can Hou et al.
Background and aims: Coronary artery disease (CAD) is among the most common type of cardiovascular diseases. The role of circular RNAs (circRNAs) and ferroptosis in CAD remains largely unexplored. The aim of this study wa...
François Roubille,Nolwenn Merlet,David Busseuil et al.
François Roubille et al.
Background and aims: The anti-inflammatory agent colchicine is gaining interest as a treatment for coronary artery disease. However, the effects of colchicine in atherosclerotic animal models are mostly unknown. This stud...
Effectiveness and safety of PCSK9 inhibitors in real-world clinical practice. An observational multicentre study. The IRIS-PCSK9I study [0.03%]
PCSK9抑制剂在真实世界临床实践中的有效性和安全性。一项观察性多中心研究。IRIS-PCSK9I研究
Marina Blanco-Ruiz,Laura Amaya-Pascasio,Reyes de Torres Chacón et al.
Marina Blanco-Ruiz et al.
Background and aims: The benefits of the PCSK9 inhibitors, alirocumab and evolocumab, in lowering LDL-cholesterol and preventing major adverse cardiac events (MACE) have been demonstrated in pivotal clinical trials. Howev...
Age dependent association between remnant cholesterol and cardiovascular disease [0.03%]
残余胆固醇与心血管疾病之间存在年龄依赖相关性
Anxin Wang,Xue Tian,Yingting Zuo et al.
Anxin Wang et al.
Background and aims: High remnant cholesterol is associated with cardiovascular disease (CVD), but whether CVD risk attributable to remnant cholesterol vary between young and later adults remains unknown. The study aimed ...
High baseline fetuin-A levels are associated with lower atherosclerotic plaque progression as measured by 3D ultrasound [0.03%]
作为基线的高水平骨保护蛋白A与通过三维超声测量显示的较低的动脉粥样硬化斑块进展相关联
Philip Sommer,Michael Schreinlechner,Maria Noflatscher et al.
Philip Sommer et al.
Background and aims: The glycoprotein fetuin-A has anti-inflammatory effects, increases insulin resistance and plays an important role in calcium metabolism. The aim of our study was to assess the predictive value of fetu...
Assessment of plasma ceramides as predictor for subclinical atherosclerosis [0.03%]
血浆神经酰胺作为亚临床动脉粥样硬化的预测指标的评估
Pashupati P Mishra,Binisha H Mishra,Leo-Pekka Lyytikäinen et al.
Pashupati P Mishra et al.
Background and aims: Ceramides have been identified as novel biomarkers for cardiovascular disease (CVD) related events and mortality but their role in etiology of subclinical atherosclerosis is unknown. We aimed to asses...
Periostin contributes to the adventitial remodeling of atherosclerosis by activating adventitial fibroblasts [0.03%]
periostin通过激活外膜成纤维细胞促进动脉粥样硬化的外膜重构
Zhonghua Wang,Guoliang Li,Mingpeng Li et al.
Zhonghua Wang et al.
Background and aims: Adventitial remodeling is an important pathological process of atherosclerosis, but cues implicated in adventitial remodeling are far from fully understood. Periostin (POSTN), a matricellular protein,...
Low-density lipoprotein cholesterol goal attainment in Germany: Results from the DA VINCI study [0.03%]
德国低密度脂蛋白胆固醇目标实现情况：DA VINCI研究结果
Ioanna Gouni-Berthold,Frank Schaper,Ulrike Schatz et al.
Ioanna Gouni-Berthold et al.
Background and aims: Cardiovascular mortality is high in Germany. For patients with high or very high cardiovascular risk, the European Society of Cardiology (ESC)/European Atherosclerosis Society (EAS) guidelines recomme...
Smoking and diabetes attenuate beneficial effects of PSCK9 inhibitors on arterial wall properties in patients with very high lipoprotein (a) levels [0.03%]
吸烟和糖尿病削弱PSCK9抑制剂在极高脂蛋白(a)水平患者中对动脉壁属性的有益影响
Andreja Rehberger Likozar,Miran Šebeštjen
Andreja Rehberger Likozar
Background and aims: Elevated lipoprotein (a) (Lp(a)) and low-density lipoprotein cholesterol levels (LDL-C) are significant residual risk factors for cardiovascular events. Treatment with protein convertase subtilisin ke...
TACE/ADAM17 substrates associate with ACS (Ep-CAM, HB-EGF) and follow-up MACE (TNFR1 and TNFR2) [0.03%]
TACE/ADAM17底物与ACS（Ep-CAM，HB-EGF）和随访MACE（TNFR1和TNFR2）相关
Melody Chemaly,Roisin McAllister,Aaron Peace et al.
Melody Chemaly et al.
Background and aims: TACE/ADAM17 is a membrane bound metalloprotease, which cleaves substrates involved in immune and inflammatory responses and plays a role in coronary artery disease (CAD). We measured TACE and its subs...