Conditional deletion of Ccl2 in smooth muscle cells does not reduce early atherosclerosis in mice [0.03%]
平滑肌细胞中Ccl2的条件性删除并不能减少小鼠早期的动脉粥样硬化病变
Stine Gunnersen,Jeong Tangkjær Shim,Fan Liu et al.
Stine Gunnersen et al.
Background and aims: C-C motif chemokine ligand 2 (CCL2) is a pro-inflammatory chemokine important for monocyte recruitment to the arterial wall and atherosclerotic plaques. Global knockout of Ccl2 reduces plaque formatio...
Acute myocardial infarction preferentially alters low-abundant, long-chain unsaturated phospholipid and sphingolipid species in plasma high-density lipoprotein subpopulations [0.03%]
急性心肌梗塞优先改变血浆高密度脂蛋白亚群中的低丰度长链不饱和磷脂和鞘脂种类
Maharajah Ponnaiah,Emile Zakiev,Marie Lhomme et al.
Maharajah Ponnaiah et al.
Aim: High-density lipoprotein (HDL) particles in ST-segment elevation myocardial infarction (STEMI) are deficient in their anti-atherogenic function. Molecular determinants of such deficiency remain obscure. ...
Plasma lipids in Pseudoxanthoma Elasticum (PXE) patients: A comparative study with population-based reference values and Non-PXE controls [0.03%]
弹性假黄瘤(PXE)患者的血浆脂类：与人群基础参考值及非PXE对照组的比较研究
Iris M Harmsen,Frank L J Visseren,Madeleine Kok et al.
Iris M Harmsen et al.
Background and aims: - Pseudoxanthoma elasticum (PXE) is a rare genetic disease caused by pathogenic mutations in the ABCC6 gene, resulting in low values of inorganic pyrophosphate (PPi). While low PPi is thought to contr...
CTCA in children with severe heterozygous familial hypercholesterolaemia: Screening for subclinical atherosclerosis [0.03%]
严重杂合子家族性高胆固醇血症儿童中的冠脉计算机断层扫描造影：筛查无症状动脉粥样硬化
M Doortje Reijman,Sibbeliene E van den Bosch,D Meeike Kusters et al.
M Doortje Reijman et al.
Familial hypercholesterolemia (FH) is one of the most common genetically inherited disorders in the world. Children with severe heterozygous FH (HeFH), i.e. untreated low-density lipoprotein cholesterol (LDL-C) levels above the 90th percent...
ITGB2 is a central hub-gene associated with inflammation and early fibro-atheroma development in a swine model of atherosclerosis [0.03%]
ITGB2是猪动脉粥样硬化模型中与炎症和早期纤维斑块形成相关的中心骨架基因
Hadjer Namous,Maria Giuseppina Strillacci,Camila Urbano Braz et al.
Hadjer Namous et al.
Background and aim: The complex dynamic interplay between different biological pathways involved in atherosclerosis development has rendered the identification of specific therapeutic targets a challenging quest. We aimed...
Fetuin-A levels in association with calcific aortic valve disease: A meta-analysis [0.03%]
与主动脉瓣钙化相关的 Fetuin-A 水平：一项荟萃分析
Muhammad Omar Larik
Muhammad Omar Larik
Background and aims: Calcific aortic valve disease (CAVD) is a common valvular disease, prevalent particularly within the older age groups. The potential use of biomarkers in diagnosing and assessing the severity of CAVD,...
The LIPL study: Postprandial lipid profile, inflammation, and platelet activity in patients with chronic coronary syndrome [0.03%]
LIPL研究：慢性冠状动脉综合征患者的餐后血脂、炎症和血小板活性
Edita Pogran,Paul M Haller,Claudia Wegberger et al.
Edita Pogran et al.
Background and aims: It is suggested that the changes in atherosclerosis happen mainly under the influence of non-fasting lipids. To date, the studies in the postprandial state were primarily performed on healthy subjects...
Prediabetes is an incremental risk factor for adverse cardiac events: A nationwide analysis [0.03%]
糖尿病前期是不良心脏事件的增量危险因素：全国范围内的分析研究
Dhairya Nanavaty,Rhea Green,Ankushi Sanghvi et al.
Dhairya Nanavaty et al.
Background and aims: Prediabetes is defined as a state of impaired glucose metabolism with hemoglobin A1c (HbA1c) levels that precede those of a diabetic state. There is increasing evidence that suggests that hyperglycemi...
High-density lipoprotein cholesterol and multiple myeloma: A systematic review and meta-analysis [0.03%]
高密度脂蛋白胆固醇与多发性骨髓瘤的关联：系统评价和Meta分析
Anastasios Makris,Antonia Pagkali,Emmanouil Nikolousis et al.
Anastasios Makris et al.
Background and aims: To systematically investigate all relevant evidence on the association between high-density lipoprotein cholesterol (HDL-C) and multiple myeloma (MM). ...
Lipoprotein(a), Interleukin-6 inhibitors, and atherosclerotic cardiovascular disease: Is there an association? [0.03%]
脂蛋白(a)、白细胞介素-6抑制剂与动脉粥样硬化性心血管疾病之间的关系？
Anastasios Makris,Fotios Barkas,Petros P Sfikakis et al.
Anastasios Makris et al.
Background and aims: Lipoprotein(a) [Lp(a)] and interleuking-6 (IL-6), an inflammation biomarker, have been established as distinct targets of the residual atherosclerotic cardiovascular disease (ASCVD) risk. We aimed to ...