In silico thermal control of spiral wave dynamics in excitable cardiac tissue [0.03%]
模拟心脏激动组织中螺旋波动力学的热调控
Rupamanjari Majumder
Rupamanjari Majumder
Self-organizing spiral waves of excitation occur in many complex excitable systems. In the heart, for example, they are associated with the occurrence of fatal cardiac arrhythmias such as tachycardia and fibrillation, which can lead to sudd...
Numerical model for electrogenic transport by the ATP-dependent potassium pump KdpFABC [0.03%]
ATP依赖型钾泵KdpFABC的电生运载数值模型研究
Adel Hussein,Xihui Zhang,David L Stokes
Adel Hussein
In vitro assays of ion transport are an essential tool for understanding molecular mechanisms associated with ATP-dependent pumps. Because ion transport is generally electrogenic, principles of electrophysiology are applicable, but conventi...
An efficient EPR spin-labeling method enables insights into conformational changes in DNA [0.03%]
一种高效的EPR旋标记方法能够使人们了解DNA构象变化的见解
Melanie Hirsch,Lukas Hofmann,Idan Yakobov et al.
Melanie Hirsch et al.
Electron paramagnetic resonance (EPR) is a powerful tool for elucidating both static and dynamic conformational alterations in macromolecules. However, to effectively utilize EPR for such investigations, the presence of paramagnetic centers...
A M Whited,Irwin Jungreis,Jeffre Allen et al.
A M Whited et al.
Significant efforts have been made to characterize the biophysical properties of proteins. Small proteins have received less attention because their annotation has historically been less reliable. However, recent improvements in sequencing,...
TSAT: Efficient evaluation software for NGS data of phage/mirror-image phage display selections [0.03%]
高效评估下一代测序数据中的噬菌体/镜像噬菌体展示选择的软件TSAT
Tim Altendorf,Jeannine Mohrlüder,Dieter Willbold
Tim Altendorf
Phage display and mirror-image phage display are commonly used techniques for the identification of binders that are specific to predefined targets. Recent studies demonstrated the effectiveness of next-generation sequencing (NGS) by increa...
Magnetic field platform for experiments on well-mixed and spatially structured microbial populations [0.03%]
用于均匀混合和空间结构微生物群体实验的磁场平台
Akila Bandara,Enoki Li,Daniel A Charlebois
Akila Bandara
Magnetic fields have been shown to affect sensing, migration, and navigation in living organisms. However, the effects of magnetic fields on microorganisms largely remain to be elucidated. We develop an open-source, 3D-printed magnetic fiel...
Nonlinear classifiers for wet-neuromorphic computing using gene regulatory neural network [0.03%]
基于基因调控神经网络的湿式类脑计算非线性分类器
Adrian Ratwatte,Samitha Somathilaka,Sasitharan Balasubramaniam et al.
Adrian Ratwatte et al.
The gene regulatory network (GRN) of biological cells governs a number of key functionalities that enable them to adapt and survive through different environmental conditions. Close observation of the GRN shows that the structure and operat...
Macy Marie Payne,Ivina Mali,Tej B Shrestha et al.
Macy Marie Payne et al.
T1 mapping is a quantitative method to characterize tissues with magnetic resonance imaging in a quick and efficient manner. It utilizes the relaxation rate of protons to depict the underlying structures within the imaging frame. While T1-m...
Estimation of the mass density of biological matter from refractive index measurements [0.03%]
基于折射率测量估算生物物质的质量密度
Conrad Möckel,Timon Beck,Sara Kaliman et al.
Conrad Möckel et al.
The quantification of physical properties of biological matter gives rise to novel ways of understanding functional mechanisms. One of the basic biophysical properties is the mass density (MD). It affects the dynamics in sub-cellular compar...
Adrián Gómez-Sánchez,Olivier Devos,Raffaele Vitale et al.
Adrián Gómez-Sánchez et al.
Time-resolved fluorescence spectroscopy plays a crucial role when studying dynamic properties of complex photochemical systems. Nevertheless, the analysis of measured time decays and the extraction of exponential lifetimes often requires ei...