Silvio Bianchi,Giacomo Donini,Maria Cristina Cannarsa et al.
Silvio Bianchi et al.
E. coli swimming motility is powered by the flagellar motor, a rotary nanomachine driven by inward proton flux through its torque-generating stators. How these proton currents arise from proton motive force is often described using a simple...
Martín A Toderi,Dzmitry Vaido,Dolores Bozovic
Martín A Toderi
While the transduction process has been well-studied in hair cells, the possible presence of mechanical perturbations in the hair cell soma has not been explored in non-mammalian species. Hair cell mechanotransduction involves rapid biophys...
Jared J Topham,Ali Al-KhazAly,Salim Ghandorah et al.
Jared J Topham et al.
Vibrational frequency profiling (VFP) using optical tweezers (OT) has emerged as a promising technique to characterize single cell behavior for diagnostic applications. These applications include cancer screening, identifying bacterial resi...
Mimicking oxidative damage in γS-crystallin with site-specific incorporation of 5-hydroxytryptophan [0.03%]
采用定点插入5-羟色氨酸的方法对γS-晶状体蛋白进行氧化损伤模拟研究
Yeonseong Seo,Zane G Long,Tsoler K Demerdjian et al.
Yeonseong Seo et al.
The human eye lens plays an essential role in vision by focusing light onto the retina. This transparent tissue consists of densely packed crystallin proteins that exhibit remarkable solu- bility despite minimal protein turnover. Post-trans...
A piperidinyl amide compound enhances Ca2+ signaling in cardiomyocytes by increasing activity of Ca2+ pump [0.03%]
一种哌啶酰胺化合物通过提高心肌细胞中Ca2+泵活性增强Ca2+信号通路
Elisa Bovo,Roman Nikolaienko,Samantha L Yuen et al.
Elisa Bovo et al.
In adult cardiomyocytes, the type 2a sarco/endoplasmic reticulum Ca2+-ATPase (SERCA2a) plays a vital role in intracellular Ca2+ regulation. Reduced SERCA2a function has been associated with decreased myocardial contraction and cardiac outpu...
Alexander C Bromley,Dana N Reinemann
Alexander C Bromley
E-hooks, or the C-terminal tails of tubulin, mediate interactions between microtubules and associated proteins. Despite their functional importance in cellular and physiological processes, their structural variability and mechanistic roles ...
Effect of Hemodynamic on Clot Formation and Flow Cessation in Patient-Specific Coronary Bifurcations [0.03%]
血流动力学对患者特定冠状动脉分叉处血栓形成及流体停止的影响研究
Mohammad Rezaei,Bahar Firoozabadi
Mohammad Rezaei
Hemostasis prevents bleeding by forming clots, though disruptions can cause insufficient or excessive clotting. Shear stress is a critical factor influencing the normal function of the blood and can stimulate the formation of unnecessary cl...
Photoelectrical modulation of Apoptosis and Autophagy via Voltage-Gated Ion Channels and Mitochondrial ROS: A mechanistic insight study of the role of VGICs [0.03%]
电压门控离子通道和线粒体ROS介导的光电调控凋亡及自噬的机制研究
Mohammad Mohammadiaria
Mohammad Mohammadiaria
Controlling cancer cell fate through membrane depolarization, reactive oxygen species (ROS) dynamics, and voltage-gated ion channel (VGIC) activation represents a rapidly advancing paradigm in bioelectronic oncology. Electrically excitable ...
Menthol Disruptive Effects on Kanamycin-Resistant Escherichia coli Energy Metabolism and Ion Fluxes [0.03%]
薄荷醇对卡那霉素抗性大肠杆菌能量代谢和离子通量的干扰效应
Silvard Tadevosyan,Siranuysh Grabska,Hovakim Grabski et al.
Silvard Tadevosyan et al.
The presented study aimed to investigate the antibacterial activity of menthol - the main component of one of the widespread plants of the Lamiaceae family - Mentha arvensis. To investigate the mode of action of menthol we studied its influ...