Dominique du Crest,Annelies Avermaete,Estella Benz et al.
Dominique du Crest et al.
Genetic and Phenotypic Features of 2 Northern Italy Families with Dowling-Degos Disease Type 4 [0.03%]
意大利两个Dowling-Degos病家系的基因和表型特征
Dario Tomasini,Carlo F Tomasini,Andrea Michelerio et al.
Dario Tomasini et al.
Dowling-Degos disease (DDD) is an autosomal dominant genodermatosis involving the folds with lentiginous hyperpigmentation and reddish-brown papules. Four main types of DDD with variable clinical presentations likely related to the heteroge...
Evaluation of Actinic Keratosis as a Risk Factor for Subsequent Nonskin Cancer Risk [0.03%]
评估光线性角化病对后续非皮肤癌风险的影响
Alexander R Gomez-Lara,Christopher D George,Chen Jiang et al.
Alexander R Gomez-Lara et al.
Actinic keratosis (AK) is a precancerous lesion that develops on chronically sun-exposed skin. Immunosuppression is known to increase the risk of both AK and other cancers, highlighting the need to evaluate potential associations between AK...
Outcome Measures in Dystrophic Calcinosis Cutis: A Systematic Review [0.03%]
dystrophic calcinosis cutis结局测量的系统评价
Jennifer Foster,Leslie Guerrero,Benjamin F Chong
Jennifer Foster
Background: Calcinosis cutis is a skin condition characterized by calcium salt deposition in the skin and subcutaneous tissues, significantly affecting patients' QOL. Owing to its rarity and lack of standardized outcome m...
SUB6 Subtilisin is Involved During the Initial Adhesion of Trichophyton benhamiae and T . mentagrophytes onto Reconstructed Human Epidermis [0.03%]
羊毛状小杆形芽生菌和小杆形芽生菌对重建的人表皮上初次黏附时SUB6蛋白酶的参与作用
Émilie Faway,Wilfried Poirier,Tsuyoshi Yamada et al.
Émilie Faway et al.
The growing incidence of dermatophytoses and the emergence of strains resistant to available antifungal agents raise the need for a better understanding of the virulence mechanisms of dermatophytes to identify new therapeutic targets. The p...
Judy Shan,Morgan Ye,Sheng-Pei Wang et al.
Judy Shan et al.
Importance: The association of diet with atopic dermatitis (AD) in children is understudied and may present an opportunity to optimize AD management in a cost-effective and low-risk manner. ...
Carvedilol Prevents UV-Induced Immunosuppression and Skin Carcinogenesis through a Mechanism Independent of β-Blockade [0.03%]
卡维地洛通过非β阻断机制预防紫外线诱导的免疫抑制和皮肤癌发生的机制研究
Ayaz Shahid,Fanglong Dong,Bradley T Andresen et al.
Ayaz Shahid et al.
Exposure to UVR suppresses the immune system, which plays a primary role in skin cancer etiology. The β-blocker carvedilol prevents UV-induced skin cancer, but the mechanism is unknown. This study examined the effects of carvedilol and its...
Metabolomic and Lipidomic Alterations in Patients with Atopic Dermatitis with Dupilumab-Associated Ocular Surface Disease [0.03%]
dupilumab相关眼表疾病患者的代谢组和脂质组变化
VijayKumar Patra,Nora Woltsche,Natalie Bordag et al.
VijayKumar Patra et al.
Atopic dermatitis (AD) is an inflammatory skin disease characterized by chronic pruritic eczema with an estimated prevalence of 10% in adults and 50% of them suffering from moderate-to-severe manifestations. Dupilumab, an IL-4/IL-13 inhibit...
Machine Learning for Early Detection of Hidradenitis Suppurativa: A Feasibility Study Using Medical Insurance Claims Data [0.03%]
利用医疗保险索赔数据进行机器学习以早期检测汗腺炎的可行性研究
Waqar Ali,Jonathan Williams,Betty Xiong et al.
Waqar Ali et al.
Patients with hidradenitis suppurativa (HS) are often misdiagnosed and may wait up to 10 years to receive a diagnosis of HS. This study aimed to predict HS diagnosis prior to actual diagnosis on the basis of previous medical history using m...
Integration of Longitudinal Clinical, Immunologic, and Environmental Data for Enhanced Disease Monitoring and Management in Pemphigus Vulgaris: A Case Study [0.03%]
天疱疮患者的纵向临床、免疫及环境数据整合促进疾病监测和管理：病例研究
Justin Baroukhian,Kristina Seiffert-Sinha,Animesh A Sinha
Justin Baroukhian
We present a case study of a patient with pemphigus vulgaris using an integrative, longitudinal approach to resolve the identities and potential contributions of a network of environmental exposures of possible clinical relevance in a genet...