Hsin-Ya Yang,Kan Zhu,Anthony Gallegos et al.
Hsin-Ya Yang et al.
The porcine excisional wound model is widely regarded as the most translationally relevant preclinical platform for studying human skin wound healing owing to its close anatomical and physiological similarity to human skin and thus can info...
Plasma proteomic profiles of patients with atopic dermatitis with moderate-to-severe pruritus treated with a single dose of nemolizumab [0.03%]
Saeko Nakajima,Hajime Iizuka,Kayo Taira et al.
Saeko Nakajima et al.
Nemolizumab demonstrates efficacy against pruritus and eczema by inhibiting IL-31 signaling in patients with atopic dermatitis. However, its effect on the systemic immune response at the molecular level remains unknown. In this study, we ai...
An updated guide to hair follicle stem cell markers and changes in their expression with aging [0.03%]
Theebah Sellathurai,Denise L Gay,Stéphane Commo et al.
Theebah Sellathurai et al.
The availability of identification markers is a major expectation in the field of stem and progenitor cell biology, whether to decipher the hierarchy of these cellular compartments or to isolate these cells for use in tissue reconstruction ...
The tumor microenvironment of cutaneous squamous cell carcinoma in high-risk patient groups: A scoping review [0.03%]
高危人群皮肤鳞状细胞癌肿瘤微环境的综述研究
Wandong Wang,Clara Harrs,Maria C Bolling et al.
Wandong Wang et al.
Cutaneous squamous cell carcinoma (cSCC) is a prevalent skin cancer in the general population that poses so far unresolved challenges in high-risk groups such as organ transplant recipients and individuals with recessive dystrophic epidermo...
Diabetes status is associated with greater disease severity in hidradenitis suppurativa [0.03%]
糖尿病状况与汗腺炎病情严重程度相关
Negar Foolad,Amy J Petty,Winston Liu et al.
Negar Foolad et al.
With the rising prevalence of endocrine conditions in the U.S., it is important to examine the relationship between diabetes mellitus and hidradenitis suppurativa (HS) severity. This retrospective, cross-sectional study evaluated whether di...
Dissecting the role of imiquimod and isostearic acid in Aldara-induced psoriasis mouse model [0.03%]
伊米喹莫德和异十八烷酸对艾达拉溶剂型软膏诱导的小鼠银屑病模型的作用机制研究
Angela Rose Liu,Sophia T Gavalas,Ananya Vadlakonda et al.
Angela Rose Liu et al.
Aldara (5% imiquimod with 25% isostearic acid [ISA]) cream-induced psoriasiform inflammation is a widely used mouse model to study psoriasis. Imiquimod is a toll-like receptor 7 (TLR7) agonist; however, the role of TLR7 signaling in human p...
The 4E-BP1 deletion modestly mitigates mTORC1-deficient epidermal barrier defects [0.03%]
4E-BP1缺失可适度缓解mTORC1缺陷引起的表皮屏障缺陷症状
Huihao Tang,Mengyu Jin,Ruyan Li et al.
Huihao Tang et al.
mTOR signaling is essential for epidermal development, yet the downstream mechanisms mediating its effects remain unclear. The 4E-BP1 (eukaryotic initiation factor 4E-binding protein 1), a major mTORC1 target that inhibits cap-dependent tra...
High-salt diet aggravates skin inflammation of psoriasis-like mouse model with CCL20‒CCR6 axis further activation [0.03%]
高盐饮食通过进一步激活CCL20-CCR6轴加重银屑病小鼠模型的皮肤炎症
Mengyan Hu,Han Cao,Li Zhang et al.
Mengyan Hu et al.
Epidermal keratinocytes are important for maintaining the skin barrier by interacting with immune cells and environmental stimuli. In this study, we reveal that a high-salt diet aggravated imiquimod-induced skin inflammation in a psoriasis-...
Corrigendum to 'Superior Antiproliferative and Enhanced Synergistic Effects of a Rock Inhibitor in Multiple Models for Keloid Disease' JID Innovations, Volume 5, Issue 6, November 2025, 100402 [0.03%]
关于“针对 keloid 病变多种模型抗增殖作用更强及协同作用增强的 ROCK 抑制剂”的勘误 JID 创新，2025年11月，卷5，期6，100402
Zeinab Ghasemishahrestani,Traci A Wilgus,Nonhlanhla P Khumalo et al.
Zeinab Ghasemishahrestani et al.
[This corrects the article DOI: 10.1016/j.xjidi.2025.100402.]. © 2026 The Author(s).
Association of immune checkpoint inhibitor-induced bullous pemphigoid with underlying cancer type: A lack of association with cancer tissue COL17A1 mutations and dysregulation [0.03%]
免疫检查点抑制剂诱导的天疱疮与基础癌症类型的相关性：与癌症组织COL17A1突变和失调无关
Rachel C Chang,Henning Olbrich,Yulu F Wang et al.
Rachel C Chang et al.
Bullous pemphigoid (BP) is an autoimmune blistering disease caused by autoantibodies to collagen type 17 (COL17A1) and is a recognized immune-related adverse event in patients receiving immune checkpoint inhibitors (ICIs). We investigated w...