Patient journey and disparities in the diagnosis and treatment of patients with hidradenitis suppurativa [0.03%]
化脓性汗腺炎患者的诊疗过程及差异性
Raj Chovatiya,Julie Gayle,Robert Low et al.
Raj Chovatiya et al.
We compared the patient journey of adult and pediatric patients with hidradenitis suppurativa (HS) and suspected HS and of patients with HS stratified by race, ethnicity, and social determinants of health. Data were from the United States P...
Keratinocytes: A key player in skin immunity and their emerging roles in secondary lymphedema [0.03%]
角蛋白细胞：皮肤免疫中的关键参与者及其在继发性淋巴水肿中作用的新角色
Xizhao Chen,Kevin Kuonqui,Sarit Pal et al.
Xizhao Chen et al.
Keratinocytes, once viewed as inert epidermal scaffolds, are now recognized as active participants in the cutaneous immunity. They orchestrate local immune responses by releasing cytokines, chemokines, and alarmins that shape innate and ada...
The human Flower isoform hFWE4 facilitates cornification in cutaneous squamous cell carcinoma [0.03%]
人花同工型hFWE4通过促进角质化促进皮肤鳞状细胞癌的形成
Justin C Rudd,Patrick T Kuwong,Rachel E Johnson et al.
Justin C Rudd et al.
Arising from epidermal keratinocytes, cutaneous squamous cell carcinoma (cSCC) is the second most common human tumor. Transformed keratinocytes in cSCC retain partial ability to execute terminal-differentiation, forming keratinized, cyst-li...
A neuroimmune axis linking S100A8/9 to itch sensitization in both bullous pemphigoid and atopic dermatitis [0.03%]
S100A8/9介导的神经免疫轴在大疱性天疱疮和特应性皮炎中的抓痒敏化作用
Katy Lawson,Yeseul Nho,Ryan Stewart et al.
Katy Lawson et al.
Bullous pemphigoid and atopic dermatitis are both inflammatory skin disorders characterized by intense pruritus and type 2 immune responses. Previous studies identified S100A8 and S100A9 as highly upregulated genes in perilesional skin of b...
Local IgG autoantibody profiles in hidradenitis suppurativa and their associations with disease features and anti-TNF therapy [0.03%]
汗腺炎患者的局部IgG自身抗体概况及其与疾病特征和抗TNF治疗的关系
Carmelo Carmona-Rivera,Liam J O&#x;Neil,Teja Mallela et al.
Carmelo Carmona-Rivera et al.
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder marked by dysregulated TNF-α signaling and aberrant adaptive immune responses, yet the role of humoral autoimmunity in disease pathogenesis remains incompletely understo...
Role of Aire and Notch4 allelic mutations in alopecia areata in C3H/HeJ mice [0.03%]
C3H/HeJ小鼠斑秃中AIRE和Notch4等位基因突变的作用
Christopher S Potter,John P Sundberg,Kathleen Silva
Christopher S Potter
Human genetic association studies suggest that AIRE (autoimmune regulator gene) and NOTCH4 are directly associated with severe forms of alopecia areata, possibly distinct subtypes of the disease. To determine whether sequence variations in ...
Corrigendum to 'Plasma proteomic profiles of patients with atopic dermatitis with moderate-to-severe pruritus treated with a single dose of nemolizumab' JID Innovations, Volume 6, Issue 3, May 2026, 100457 [0.03%]
关于“纳莫利珠单抗治疗中重度瘙痒性特应性皮炎患者血浆蛋白质组特征”的勘误，JID创新卷第6期，第3期，2026年5月，100457
Saeko Nakajima,Hajime Iizuka,Kayo Taira et al.
Saeko Nakajima et al.
[This corrects the article DOI: 10.1016/j.xjidi.2026.100457.]. © 2026 The Author(s).
Development of a noninvasive device and method for measuring immune parameters in skin disease [0.03%]
一种用于测量皮肤病免疫参数的非侵入式装置和方法的研发
Eveline D de Geus,Sem Koornneef,Nalini C Sreeram et al.
Eveline D de Geus et al.
Diagnosis, treatment, and monitoring of skin disease, including psoriasis and atopic dermatitis (AD), currently depend on clinical evaluation. Access to easily accessible and reliable biomarkers would facilitate diagnosis, treatment, and mo...
ChatGPT, Gemini, and Claude in clinical and dermoscopic image analysis of basal cell carcinoma and its common mimickers: A comparative performance analysis [0.03%]
临床和皮肤镜图像分析中(ChatGPT、Gemini和Claude在基底细胞癌及其常见模拟病分析中的比较性能分析)
Mehdi Boostani,Christos C Zouboulis,Giovanni Pellacani et al.
Mehdi Boostani et al.
Basal cell carcinoma (BCC) is the most common skin cancer. Off-the-shelf multimodal large language models are widely accessible, yet their performance for BCC remains unclear. The aim of this study was to assess BCC detection (BCC vs non-BC...
Christina E Bax,Livia Casciola-Rosen,David Fiorentino
Christina E Bax
Dermatomyositis (DM) is a cardinal example of an autoimmune rheumatic disease associated with an increased risk of cancer. Research over the past 2 decades highlights that specific DM autoantibodies are associated with overall risk of cance...