Lower Neighborhood Socioeconomic Status Is Associated with Moderate-Severe Hidradenitis Suppurativa: A Cross-Sectional Study [0.03%]
较低的社会经济状态与中重度汗腺炎相关:一项横断面研究
Maria Elena Sanchez-Anguiano,Krittin Supapannachart,Erin H Amerson et al.
Maria Elena Sanchez-Anguiano et al.
Neighborhood factors may impact hidradenitis suppurativa (HS) severity. Neighborhood environment influences obesity and smoking, which may affect HS severity. Longer time to diagnosis is correlated with worse HS severity at diagnosis, and d...
Remote Skin and Blood Sampling for Translational Connective Tissue Disorder Research: A Proof-of-Concept Pilot Study [0.03%]
用于转化结缔组织病研究的远程皮肤和血液采样:概念验证试点研究
Dany Alkurdi,Saeed Shakiba,Isabel Okinedo et al.
Dany Alkurdi et al.
Remote, noninvasive biospecimen collection methods can address geographic and mobility-related barriers to participation in translational research for connective tissue disorders. We evaluated the feasibility of combining noninvasive skin t...
Squaric Acid Dibutylester Promotes Innate Immune-Driven Hair Growth with CD206+ Macrophage Accumulation in the Dermis [0.03%]
琥珀酸二丁酯通过促进真皮CD206+巨噬细胞积累诱导先天免疫依赖的毛发生长
Koichi Tomii,Madoka Ozawa,Yasuhiro Kanda et al.
Koichi Tomii et al.
Alopecia areata (AA) is an autoimmune skin disorder that causes hair loss. Squaric acid dibutylester (SADBE) is used for AA treatment as a topical immunotherapy that promotes hair growth by inducing allergic contact dermatitis in skin lesio...
High Prevalence of Metabolic Dysfunction-Associated Steatotic Liver Disease in Patients with Hidradenitis Suppurativa: A Guide to Easily Assess the Clinical Risk of Comorbid Liver Disease [0.03%]
汉德伦综合征患者中代谢功能异常相关性肝脂肪变性疾病高发:一种简单评估合并症肝脏疾病临床风险的方法
Verena G Frings,Maxine Gläsel,Monika Rau et al.
Verena G Frings et al.
Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition associated with considerable comorbidity. The link between HS and metabolic dysfunction-associated steatotic liver disease (MASLD) is of particular interest owing to sha...
SOX2 Is a Potential Diagnostic Biomarker and Anticancer Target in Cutaneous Squamous Cell Carcinoma in Dystrophic Epidermolysis Bullosa: A Case Series Study [0.03%]
SOX2是营养不良性大疱表皮松解症皮肤鳞状细胞癌的潜在诊断生物标志物和抗肿瘤靶点:一系列病例研究
Clara Harrs,Marieke Bolling,Peter van den Akker et al.
Clara Harrs et al.
A serious complication in epidermolysis bullosa (EB), particularly in recessive dystrophic EB, is the development of aggressive cutaneous squamous cell carcinoma with a high risk for metastasis and poor survival outcomes. The current standa...
Characterizing Keratinocyte-Derived Extracellular Vesicles in UVB-Irradiated Murine Skin [0.03%]
UVB照射小鼠皮肤来源的角质细胞外泌体的表征研究
Ahmed Eldaboush,Cristina Ricco,Luca Musante et al.
Ahmed Eldaboush et al.
UVB radiation is a potent trigger for photosensitive autoimmune diseases, yet the mechanism through which UVB-induced superficial epidermal damage drives deeper systemic inflammation remains poorly understood. Extracellular vesicles (EVs) h...
Increased Risk of Postoperative Complications in Patients with Hypertension Undergoing Mohs Micrographic Surgery [0.03%]
高血压患者接受莫尔斯显微手术后并发症风险增加
Alexandra Elder,Henry Y Yang,Megan ODonnell-Cappelli et al.
Alexandra Elder et al.
Hypertension has been previously associated with higher intraoperative bleeding risk in patients undergoing Mohs micrographic surgery. However, the risks of common postoperative Mohs micrographic surgery complications have not been substant...
ZNF750 Loss of Function Drives Spontaneous Psoriasiform Skin Inflammation [0.03%]
锌指抗炎蛋白ZNF750功能丧失可诱发自发性银屑病样皮肤炎症反应
Hilla Levi,Topaz Alfer,Roi Gazit et al.
Hilla Levi et al.
Epidermal keratinocytes are not only crucial for maintaining skin barrier physical functions but also play various roles in the initiation, progression, and maintenance phases of skin inflammation. ZNF750 is an epithelial-specific transcrip...
Racial Differences in Work Relative Value Units for Outpatient Pediatric Dermatology Visits [0.03%]
儿科皮肤科门诊工作的相对价值单位的种族差异
Udeyvir S Cheema,Beiyu Liu,Ethan Borre et al.
Udeyvir S Cheema et al.
Measures of clinical productivity may tilt financial incentives toward providing care to specific patient populations, reinforcing inequitable care. Race, sex, and age have been shown to influence differences in work relative value units (w...
Peptide Epitopes of NC16A BP180 in the Diagnostics of Bullous Pemphigoid [0.03%]
用于诊断大疱性天疱疮的NC16a和BP180肽抗原表位
Simon D Lytton,Christine Wagger,Damian Meyersburg et al.
Simon D Lytton et al.
Bullous pemphigoid is a severe autoimmune blistering skin disorder causing significant morbidity and mortality among the elderly. Improved diagnostic strategies rely on the identification of autoantigen epitopes recognized by pathogenic aut...