Alexandria M Brown,Yao Li,Candice L Hinkston et al.
Alexandria M Brown et al.
The International Classification of Diseases: 10th Revision (effective from October 2015) included indoor tanning diagnosis codes for the first time. The majority of data on indoor tanning is self-reported. We used a large claims dataset to...
Unsupervised Phenotype-Based Clustering of Clinicopathologic Features in Cutaneous Melanoma [0.03%]
基于无监督表型分组的皮肤黑色素瘤临床病理特征聚集分析
Sarem Rashid,Nikolai Klebanov,William M Lin et al.
Sarem Rashid et al.
Pathogenic phenotypes in cutaneous melanoma have been vastly cataloged, although these classifications lack concordance and are confined to either morphological or molecular contexts. In this study, we perform unsupervised k-medoids cluster...
Using a Machine Learning Approach to Identify Low-Frequency and Rare FLG Alleles Associated with Remission of Atopic Dermatitis [0.03%]
利用机器学习方法识别与特应性皮炎缓解相关的低频和罕见FLG等位基因
Ronald Berna,Nandita Mitra,Ole Hoffstad et al.
Ronald Berna et al.
Atopic dermatitis (AD) is a common relapsing inflammatory skin disease. FLG is the gene most consistently associated with AD. Loss-of-function variants in FLG have been previously associated with AD. Low-frequency and rare alleles (minor al...
Evidence-Based Consensus Recommendations for the Evolving Treatment of Patients with High-Risk and Advanced Cutaneous Squamous Cell Carcinoma [0.03%]
高危和晚期皮肤鳞状细胞癌的治疗方法循证共识推荐意见
Guilherme Rabinowits,Michael R Migden,Todd E Schlesinger et al.
Guilherme Rabinowits et al.
Cutaneous squamous cell carcinoma is the second most common skin cancer in the United States. Currently, there is no standardized management approach for patients with cutaneous squamous cell carcinoma who develop metastatic or locally adva...
A Sensitization-Free Dimethyl Fumarate Prodrug, Isosorbide Di-(Methyl Fumarate), Provides a Topical Treatment Candidate for Psoriasis [0.03%]
异山梨醇二(甲基富马酸)酯是一种无敏化性的二甲基富马酸前药，可作为银屑病的外用候选药物
Krzysztof Bojanowski,Collins U Ibeji,Parvesh Singh et al.
Krzysztof Bojanowski et al.
Dimethyl fumarate (DMF) is an effective oral treatment for psoriasis administered in Europe for nearly 60 years. However, its potential has been limited by contact dermatitis that prohibits topical application. This paper characterizes a DM...
Juan-Manuel Leyva-Castillo,Raif S Geha
Juan-Manuel Leyva-Castillo
In a new article published in JID Innovations, Nakatani-Kusakabe et al. (2021) show that type 2 innate lymphoid cells (ILC2s) in the skin of mice with IL-33 overexpression in keratinocytes are heterogeneous and consist of two distinct popul...
Russell P Hall rd
Russell P Hall rd
Anushka Dikshit,Junqi Lu,Amy E Ford et al.
Anushka Dikshit et al.
Increased breakdown of glucose through glycolysis in both aerobic and anaerobic conditions is a hallmark feature of mammalian cancer and leads to increased production of L-lactate. The high-level lactate present within the tumor microenviro...
A Literature Review of Real-World Effectiveness and Safety of Dupilumab for Atopic Dermatitis [0.03%]
杜匹鲁单抗治疗特应性皮炎真实世界有效性和安全性的文献回顾
Masahiro Kamata,Yayoi Tada
Masahiro Kamata
Atopic dermatitis (AD) is a chronic inflammatory skin disease with pruritus, characterized by recurrent eczema with exacerbations and remissions. AD impairs patients' QOL and places a heavy burden on patients. Recently, dupilumab, an anti-I...
Hair Follicle Grafting Therapy Promotes Re-Emergence of Critical Skin Components in Chronic Nonhealing Wounds [0.03%]
毛囊移植治疗可促进慢性难愈性创面关键皮肤成分的再生式 emergence 应译为“再现”或“重新出现”更符合原文意思，故标题应译为：毛囊移植物促进慢性难愈性创面关键皮肤成分的再生成为更加合适的翻译。
Dyuti Saha,Sujaya Thannimangalath,Leelavathy Budamakuntla et al.
Dyuti Saha et al.
An exploding public health crisis is the exponential growth in the incidence of chronic nonhealing ulcers associated with diseases such as diabetes. Various modalities have been developed to stimulate wound closure that is otherwise recalci...