Therapeutic guidance of tumor mutation burden on immune checkpoint inhibitors in advanced non-small cell lung cancer: a systematic review and comprehensive meta-analysis [0.03%]
基于肿瘤突变负荷指导晚期非小细胞肺癌免疫检查点抑制剂治疗的系统评价和综合meta分析
Jie Zhao,Yiting Dong,Hua Bai et al.
Jie Zhao et al.
Background: Tumor mutation burden (TMB) remains a promising but ambiguous predictive biomarker for the efficacy of immune checkpoint inhibitors (ICIs). We investigated the predictive value of TMB in patients with advanced...
Pretreatment systemic immune-inflammation index predicts survival for non-metastatic nasopharyngeal carcinoma: two independent institutional studies [0.03%]
术前系统性免疫-炎症指数可预测非转移性鼻咽癌患者的生存情况：两项独立机构的研究
Fengge Zhou,Liting Liu,Xiaodong Huang et al.
Fengge Zhou et al.
Objective: This study aimed to evaluate the prognostic value of the pretreatment systemic immune-inflammation index (SII) in non-metastatic nasopharyngeal carcinoma (NPC). ...
Prevalence and outcomes of focal ablation versus prostatectomy for elderly patients with prostate cancer: a population-based study [0.03%]
一项基于人群的研究：对于老年前列腺癌患者经皮局部消融与前列腺切除术的流行度及预后的比较
Yongqiang Zheng,Yuzhong Ye,Lezong Chen et al.
Yongqiang Zheng et al.
Background: Despite rapid advances in the treatment of prostate cancer (PCa), the optimal treatment for elderly patients with PCa remains unclear due to a lack of high-quality evidence. This study aimed to evaluate whethe...
Rongshou Zheng,Siwei Zhang,Hongmei Zeng et al.
Rongshou Zheng et al.
Background: National Cancer Center (NCC) of China annually reports the nationwide statistics for cancer incidence and mortality using population-based cancer registry data from all available cancer registries in China. ...
New substituted molecular classifications of advanced gastric adenocarcinoma: characteristics and probable treatment strategies [0.03%]
晚期胃腺癌新的分子替代分类：特点及可能的治疗策略
Bingzhi Wang,Chunxia Du,Lin Li et al.
Bingzhi Wang et al.
Background: Gastric adenocarcinoma (GA) is a heterogeneous tumor, and the accurate classification of GA is important. Previous classifications are based on molecular analysis and have not focused on GA with the primitive ...
Cost-effectiveness of lung cancer screening by low-dose CT in China: a micro-simulation study [0.03%]
中国肺癌低剂量螺旋CT筛查成本效益的微观模拟研究
Yihui Du,Yanju Li,Grigory Sidorenkov et al.
Yihui Du et al.
Background: The effectiveness of lung cancer screening with low-dose computed tomography (LDCT) has been established. The current study evaluates the cost-effectiveness of lung cancer screening with LDCT in a general popu...
Understanding the role of endothelial cells in brain tumor formation and metastasis: a proposition to be explored for better therapy [0.03%]
探讨内皮细胞在脑肿瘤发生和转移中的作用：有待研究的更好疗法
Tejas Girish Agnihotri,Sagar Salave,Tanuja Shinde et al.
Tejas Girish Agnihotri et al.
Glioblastoma is one of the most devastating central nervous system disorders. Being a highly vascular brain tumor, it is distinguished by aberrant vessel architecture. This lends credence to the idea that endothelial cells (ECs) linked with...
The potential role of minimal/molecular residual disease in colorectal cancer: curative surgery, radiotherapy and beyond [0.03%]
结直肠癌微小/分子残留病灶的潜在作用：根治性手术、放疗等
Meiyi Xu,Tianhao Shi,Ruilian Xu et al.
Meiyi Xu et al.
Detection of minimal/molecular residual disease (MRD) based on ctDNA assay develops from hematological malignancies to solid tumors. Generally, there are two mainstream assays in MRD testing technology: tumor-informed and tumor-agnostic. Fo...
Quality control indices for standardized diagnosis and treatment of esophageal cancer in China (2022 edition) [0.03%]
中国食管癌规范化诊疗质量控制指标（2022版）
Ruixiang Zhang,Zhen Wang,Xiaozheng Kang et al.
Ruixiang Zhang et al.
Esophageal cancer (EC) is particularly common in China. With the continuing progress of multi-disciplinary therapy including early screening, minimally invasive techniques, radiotherapy and chemotherapy, the 5-year survival of EC has been i...
Vaccination strategies for oncology patients: the need for a pro-active approach [0.03%]
肿瘤患者的疫苗接种策略：需要采取主动的方法
Karen H Keddy,Jason Naicker,Suzanna M Budavari et al.
Karen H Keddy et al.