Minimally invasive versus open esophagectomy for resectable thoracic esophageal cancer (NST 1502): a multicenter prospective cohort study [0.03%]
微创与开放食管切除术治疗可切除性胸部食管癌患者的疗效对比研究（NST1502）：一项多中心前瞻性队列研究
Yousheng Mao,Shugeng Gao,Yin Li et al.
Yousheng Mao et al.
Background: Whether minimally invasive esophagectomy (MIE) is superior to open esophagectomy (OE) in the treatment of esophageal squamous cell carcinoma (ESCC) is still uncertain. Therefore, this multicenter prospective s...
Quality of life and survival outcomes of patients with inoperable esophageal squamous cell carcinoma after definitive radiation therapy: A multicenter retrospective observational study in China from 2015 to 2016 [0.03%]
2015年至2016年中国不可手术食管鳞癌患者根治性放射治疗后的生存和生活质量的多中心回顾性研究
Xin Wang,Fei Liang,Xiaomin Wang et al.
Xin Wang et al.
Objectives: To investigate the health-related quality of life (HRQL) of long-term survivors of inoperable esophageal squamous cell carcinoma (ESCC) treated with definitive radiation therapy, the real-world trends in the u...
Heterogeneity and function of cancer-associated fibroblasts in renal cell carcinoma [0.03%]
肾细胞癌相关成纤维细胞的异质性和功能属性分析
Haijia Tang,Wenhao Xu,Jiahe Lu et al.
Haijia Tang et al.
With the advancement of anticancer therapy, there is increasing interest in understanding the tumor microenvironment (TME). Cancer-associated fibroblasts (CAFs) play a pivotal role in the TME and have been the focus of much research in rece...
Quality assurance and safety of hippocampal avoidance prophylactic cranial irradiation in the multicenter randomized phase III trial (NCT01780675) [0.03%]
多中心随机三期临床试验(NCT01780675)中海马回避预防性全脑照射的质量控制和安全问题
Oscar Candiff,José Belderbos,Anne Lisa Wolf et al.
Oscar Candiff et al.
Objective: NCT01780675, a multicenter randomized phase III trial of prophylactic cranial irradiation (PCI) versus PCI with hippocampal sparing in small cell lung cancer (SCLC) investigated neurocognitive decline and safet...
National Cancer Institute's early detection research network: a model organization for biomarker research [0.03%]
国立癌症研究所的早期检测研究网络：生物标志物研究的理想组织模型
Paul D Wagner,Sudhir Srivastava
Paul D Wagner
For many cancers a primary cause of poor survival is that they are detected at a late stage when therapies are less effective. Although screening methods exist to detect some types of cancer at an early stage, there are currently no effecti...
Docetaxel plus S-1 versus docetaxel plus capecitabine as first-line treatment for advanced breast cancer patients: a prospective randomized phase II study [0.03%]
多西他赛联合S-1与多西他赛联合卡培他滨一线治疗晚期乳腺癌患者：一项前瞻性随机Ⅱ期临床试验
Nilupai Abudureheiyimu,Yun Wu,Qing Li et al.
Nilupai Abudureheiyimu et al.
Background: This study was conducted to evaluate the efficacy and safety of docetaxel/S-1 (TS) compared with docetaxel/capecitabine (TX) as a first-line treatment for advanced breast cancer. ...
Huiyao Huang,Jingting Du,Xinyu Meng et al.
Huiyao Huang et al.
Objective: To deliver a comprehensive picture of the landscape and changing trend of trials and approvals on targeted anticancer drugs in China from 2012 to 2021. ...
Precision based approach to tailoring radiotherapy in the multidisciplinary management of pediatric central nervous system tumors [0.03%]
基于精确性的放射治疗的儿科中枢神经系统肿瘤多学科管理中的应用方法研究
Christina Phuong,Bo Qiu,Sabine Mueller et al.
Christina Phuong et al.
Modern day survivorship from childhood malignancies is estimated to be over 80%. However, central nervous system tumors remain the leading cause of cancer mortality in children and is the most common solid tumor in this population. Improved...
Weibo Yu,Shivani Sharma,Elizabeth Rao et al.
Weibo Yu et al.
The study of physical and mechanical features of cancer cells, or cancer cell mechanobiology, is a new frontier in cancer research. Such studies may enhance our understanding of the disease process, especially mechanisms associated with can...
The time-series behavior of systemic inflammation-immune status in predicting survival of locally advanced non-small cell lung cancer treated with chemoradiotherapy [0.03%]
局部晚期非小细胞肺癌化疗联合放疗生存预测的系统性炎症免疫状态时间序列行为学研究
Tao Zhang,Jianyang Wang,Daquan Wang et al.
Tao Zhang et al.
Background: Systematic inflammation is believed to play a crucial role in tumorigenesis and metastasis. This study aims at evaluating the prognostic value of time-series behavior of systematic inflammation-immune status b...