Patient-derived organoids (PDOs) and PDO-derived xenografts (PDOXs): New opportunities in establishing faithful pre-clinical cancer models [0.03%]
患者来源器官样体（PDO）和PDO异种移植物（PDOX）：建立忠实的临床前癌症模型的新机遇
Ergang Wang,Kun Xiang,Yun Zhang et al.
Ergang Wang et al.
One of the major bottlenecks in advancing basic cancer research and developing novel cancer therapies is the lack of in vitro pre-clinical models that faithfully recapitulate tumor properties in the patients. Monolayer cultures of cancer ce...
Characteristics of tumor microenvironment and novel immunotherapeutic strategies for non-small cell lung cancer [0.03%]
非小细胞肺癌肿瘤微环境的特征及新型免疫治疗策略
Fen Wang,Mingyi Yang,Weichi Luo et al.
Fen Wang et al.
Immune checkpoint inhibitor-based immunotherapy has revolutionized the treatment approach of non-small cell lung cancer (NSCLC). Monoclonal antibodies against programmed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) are widely used in clinica...
Risk assessment of self-sampling HPV tests based on PCR, signal amplification to guide the appropriate screening intervals: A prospective study in China [0.03%]
基于PCR、信号扩增的自我取样HPV检测风险评估：一项前瞻性研究
Xuelian Zhao,Shangying Hu,Shuang Zhao et al.
Xuelian Zhao et al.
Objective: We assessed the longitudinal risk of developing cervical intraepithelial neoplasia (CINs) with self-sampling human papillomavirus (HPV) tests, based on polymerase chain reaction (PCR) and signal amplification (...
Jiajun Luo,Andrew Craver,Kayla Moore et al.
Jiajun Luo et al.
Towards automated organs at risk and target volumes contouring: Defining precision radiation therapy in the modern era [0.03%]
迈向自动勾画危险器官和目标体积：定义现代精确放疗
Dakai Jin,Dazhou Guo,Jia Ge et al.
Dakai Jin et al.
Precision radiotherapy is a critical and indispensable cancer treatment means in the modern clinical workflow with the goal of achieving "quality-up and cost-down" in patient care. The challenge of this therapy lies in developing computeriz...
Kaiyong Zou,Peiyuan Sun,Huang Huang et al.
Kaiyong Zou et al.
Lung cancer is one of the leading causes of cancer incidence and mortality worldwide. While smoking, radon, air pollution, as well as occupational exposure to asbestos, diesel fumes, arsenic, beryllium, cadmium, chromium, nickel, and silica...
Axillary lymph node dissection plus radiotherapy may be an optimal strategy for patients with occult breast cancer [0.03%]
腋窝淋巴结清扫联合放疗可成为隐匿性乳腺癌患者的治疗优选策略
Lixi Li,Di Zhang,Tingyu Wen et al.
Lixi Li et al.
Background: Because of the rarity of occult breast cancer (OBC) and limited experience in OBC treatment, the optimal treatment strategy is unknown. This study aimed to compare the efficacy of axillary lymph node dissectio...
Psychological distress and quality of life in Chinese early-stage breast cancer patients throughout chemotherapy [0.03%]
中国早期乳腺癌患者化疗期间的心理痛苦和生活质量研究
Bo Lan,Dan Lv,Min Yang et al.
Bo Lan et al.
Background: Breast cancer survivors with psychological problems have higher mortality than those without. Therefore, it is important to monitor and manage their psychological status. This study mainly aimed to dynamically...
The role of stereotactic body radiotherapy in hepatocellular carcinoma: guidelines and evidences [0.03%]
立体定向身体放射治疗在肝细胞癌中的作用：指南和证据
Yulin Hu,Caining Zhao,Ren Ji et al.
Yulin Hu et al.
Hepatocellular carcinoma (HCC) is a common malignancy with high mortality rates. While surgery can be curative in early-stage disease, 80% of patients cannot undergo surgical resection. Stereotactic body radiotherapy (SBRT), an emerging, no...