Ke-Xin Song,Jun-Xian Wang,De Huang
Ke-Xin Song
Cellular senescence is characterized by a generally irreversible cell cycle arrest and the secretion of bioactive factors known as the senescence-associated secretory phenotype (SASP). In an oncogenic context, senescence is considered a tum...
Mutation-based circulating tumor DNA detection approach to monitoring the therapy response in breast cancer [0.03%]
基于突变的循环肿瘤DNA检测在监测乳腺癌治疗反应中的应用
Jiaqi Liu,Yansong Huang,Xiang Wang
Jiaqi Liu
Identification of plasma proteomic signatures associated with the progression of cardia gastric cancer and precancerous lesions [0.03%]
与胃癌管状部位癌症进展和癌前病变相关的血浆蛋白质组标志物的识别
Jianhua Gu,Shuanghua Xie,Xinqing Li et al.
Jianhua Gu et al.
Objective: Considering that there are no effective biomarkers for the screening of cardia gastric cancer (CGC), we developed a noninvasive diagnostic approach, employing data-independent acquisition (DIA) proteomics to id...
Targeted drug delivery systems for pancreatic ductal adenocarcinoma: overcoming tumor microenvironment challenges with CAF-specific nanoparticles [0.03%]
针对胰腺导管腺癌的药物递送系统：通过CAF特异性纳米颗粒克服肿瘤微环境挑战
Xinming Su,Zehua Wang,Shiwei Duan
Xinming Su
Pancreatic ductal adenocarcinoma (PDAC) stands as a profoundly heterogeneous and aggressive malignancy, manifesting a discouragingly limited response to conventional therapeutic interventions. Within the intricate tapestry of the tumor micr...
Febrile neutropenia: Clinical approach to a controversial presentation of the COVID-19 era [0.03%]
新冠肺炎时代的发热性中性粒细胞减少：一种颇具争议的临床表现及其处理方法
Mohammad-Salar Hosseini
Mohammad-Salar Hosseini
Consensus on clinical diagnosis and medical treatment of HER2-low breast cancer (2022 edition) [0.03%]
HER2低表达乳腺癌临床诊断和治疗专家共识（2022版）
Bu Hong,Fan Ying,Fan Zhaoqing et al.
Bu Hong et al.
Treatment of breast cancer with low expression of human epidermal growth factor receptor 2 (HER2; HER2-low) has drawn much attention in recent years. With the proven therapeutic effect of trastuzumab deruxtecan (T-DXd) in patients with HER2...
Chinese expert consensus on the diagnosis and treatment of bone metastasis in lung cancer (2022 edition) [0.03%]
中国肺癌骨转移诊断治疗专家共识(2022版)
Jianchun Duan,Wenfeng Fang,Hairong Xu et al.
Jianchun Duan et al.
Lung cancer is the leading cause of cancer-related deaths worldwide. Bone is a common metastatic site of lung cancer, about 50% of bone metastatic patients will experience skeletal related events (SREs). SREs not only seriously impact the q...
Etiology of non-Hodgkin lymphoma: A review from epidemiologic studies [0.03%]
非霍奇金淋巴瘤的病因学：来自流行病学研究的综述
Jiajun Luo,Andrew Craver,Kendall Bahl et al.
Jiajun Luo et al.
Non-Hodgkin lymphoma (NHL) contributes to significant cancer burden and mortality globally. In recent years, much insight into the causes of NHL has been gained by evaluating global differences through international collaboration and data p...
Chinese Society of Clinical Oncology (CSCO): Clinical guidelines for the diagnosis and treatment of pancreatic cancer [0.03%]
中国临床肿瘤学会胰腺癌指南2020版
Jiujie Cui,Feng Jiao,Qi Li et al.
Jiujie Cui et al.
Pancreatic cancer is one of the leading causes of cancer-related mortality in both developed and developing countries. The incidence of pancreatic cancer in China accounts for about a quater of the global incidence, and the epidemiological ...
The roles of histone modifications in tumorigenesis and associated inhibitors in cancer therapy [0.03%]
组蛋白修饰在肿瘤发生中的作用及其抑制因子在癌症治疗中的应用
Yunkai Yang,Min Zhang,Yan Wang
Yunkai Yang
Histone modifications are key factors in chromatin packaging, and are responsible for gene regulation during cell fate determination and development. Abnormal alterations in histone modifications potentially affect the stability of the geno...