Precision Medicine Using Simultaneous Monitoring and Assessment with Imaging and Biomarkers to Manage Mechanical Ventilation in ARDS [0.03%]
基于影像学和生物标志物的实时监测与评估进行精准医疗以指导ARDS患者机械通气的个体化设置与调整
Megan Abbott,Yuchong Li,Laurent Brochard et al.
Megan Abbott et al.
Acute respiratory distress syndrome (ARDS) has a ~ 40% mortality rate with an increasing prevalence exacerbated by the COVID-19 pandemic. Mechanical ventilation is the primary means for life-saving support to buy time for lung healing in AR...
Evidence Based Management of Acute Heart Failure in the Era of COVID-19 Pandemic [0.03%]
新冠肺炎疫情下的急性心力衰竭循证管理
Lexin Wang
Lexin Wang
This editorial is to highlight current issues of heart failure management during COVID-19 pandemic. Keywords: ...
Zhi Mao,Chao Liu,Qinglin Li et al.
Zhi Mao et al.
There is a growing demand for intensive care units, but there is a relative shortage of medical staff. Intensive care work is heavy and stressful. Optimizing the working conditions and processes of the intensive care unit is of great signif...
Ning Luo,Mengdie Li,Ming Xu et al.
Ning Luo et al.
Severe fever with thrombocytopenia syndrome (SFTS) is a new infectious disease first discovered in Ta-pieh Mountains in central China in 2009. It is caused by a novel bunyavirus infection (SFTSV). Since the first discovery of SFTSV, there h...
Effect of the Timing of Amubarvimab/Romlusevimab (BRII-196/198) Administration on Progression to Severe Disease in Elderly Patients with COVID-19 Infection: A Retrospective Cohort Study [0.03%]
不同给药时间对老年新冠感染患者的临床进展影响：安巴韦林罗米司韦单抗(BRII-196/198)真实世界队列研究
Yonghao Xu,Ying Liu,Ruiqiang Zheng et al.
Yonghao Xu et al.
Objective: Early intervention with neutralizing antibodies is considered to be effective in preventing disease progression in patients with mild to moderate COVID-19 infection. Elderly patients are the most susceptible an...
Effect of Sivelestat in the Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis [0.03%]
svelestat治疗急性肺损伤和急性呼吸窘迫综合征疗效的系统评价和 meta 分析
Qiongli Ding,Yi Wang,Chunbo Yang et al.
Qiongli Ding et al.
Background: The efficacy of neutrophil elastase inhibitor sivelestat in the treatment of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) remains controversial. A systematic review and meta-analysis ...
Clinical Utility of the Sivelestat for the Treatment of ALI/ARDS: Moving on in the Controversy? [0.03%]
二氧化硫清除剂治疗ALI/ARDS的临床疗效：争论中的进展？
Qiongli Ding,Yi Wang,Chunbo Yang et al.
Qiongli Ding et al.
Acute respiratory distress syndrome (ARDS) is a serious condition that can arise following direct or indirect acute lung injury (ALI). It is heterogeneous and has a high mortality rate. Supportive care is the mainstay of treatment and there...
Robustness of Significant Dichotomous Outcomes in Randomized Controlled Trials in the Treatment of Patients with COVID-19: A Systematic Analysis [0.03%]
随机对照试验中COVID-19患者治疗的显著二分类结果的稳健性系统分析
Qi Liu,Hong Chen,Yonghua Gao et al.
Qi Liu et al.
Purpose: Significant results of randomized controlled trials (RCTs) should be properly weighed. This study adopted fragility index (FI) to evaluate the robustness of significant dichotomous outcomes from RCTs on coronavir...
Early Awake Prone Position Combined with High-Flow Nasal Oxygen Therapy in Severe COVID-19: A Case Series [0.03%]
早期清醒俯卧位联合高流量鼻导管氧疗治疗重症COVID-19的病例系列研究
Y Chengfen,Z Yongle,L Jianguo et al.
Y Chengfen et al.
Background: Awake prone positioning has been used for non-intubated patients with COVID-19-related acute hypoxaemic respiratory failure, but the results are contradictory. We aimed to highlight the role of awake prone pos...
Andrographolide Suppresses Expressions of Coagulation and Fibrinolytic Inhibition-Related Factors in LPS-Induced Alveolar Epithelial Cell Type II via NF-κB Signal Pathway In Vitro [0.03%]
穿心莲内酯通过NF-κB信号通路抑制LPS诱导的II型肺泡上皮细胞中与凝血和纤溶抑制相关因子的表达体外研究
Guixia Yang,Xiang Li,Qing Li et al.
Guixia Yang et al.
Background: Andrographolide (Andro) has been confirmed to ameliorate alveolar hypercoagulation and fibrinolysis inhibition via NF-κB pathway in acute respiratory distress syndrome (ARDS), but the specific target of Andro...