Diversity oriented total synthesis (DOTS) of pyridoquinazolinone alkaloids and their analogues [0.03%]
基于多样性的定向全合成（DOTS）并研究吡啶嵌苯并喹唑酮类生物碱及其类似物
Sivappa Rasapalli,Yanchang Huang,Vamshikrishna Reddy Sammeta et al.
Sivappa Rasapalli et al.
A short diversity oriented total synthesis (DOTS) of substituted rutaecarpines, homo-luotonins, homo-vasicinone, homo-isaindigotones and homo-vasnetine has been achieved from the key tricyclic intermediate. The [6,6,6] tricyclic ketone, the...
Mohammad Nuruzzaman,Zeinab M Nizam,Jun Ohata
Mohammad Nuruzzaman
While their broad utility in various chemistry fields were well recognized for decades, fluoroalcohols have recently emerged as a unique solvent system for bioconjugation development. This review describes examples and roles of fluoroalcoho...
Enantioselective α-heterofunctionalization reactions of catalytically generated C1-Lewis base enolates [0.03%]
催化生成C1-路易斯碱烯醇化物的对映选择性α-杂功能化反应
Magdalena Piringer,Lotte Stockhammer,Lukas Vogl et al.
Magdalena Piringer et al.
Chiral Lewis base (LB) organocatalysis has emerged as a powerful covalent catalysis concept which allows for highly selective asymmetric C-C and C-heteroatom bond formations. Considering significant recent progress in the development of str...
Synthesis of (-)-melazolide B, a degraded limonoid, from a natural terpene precursor [0.03%]
由天然萜类前体合成梅阿唑酮B(-)-melazolide B
Yannan Liu,Alexander W Schuppe,Yizhou Zhao et al.
Yannan Liu et al.
Degraded limonoids are a subclass of limonoid natural products that derive from ring-intact or ring-rearranged limonoids. Establishment of robust synthetic routes to access them could provide valuable materials to identify the simplest acti...
Chandra Shekhar,Rajesh Nasam,Siva Ramakrishna Paipuri et al.
Chandra Shekhar et al.
The emergence and rapid spread of coronavirus disease 2019 (COVID-19), a potentially fatal disease, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has swiftly led to public health crisis worldwide. Hence vaccines an...
Working at the interfaces of data science and synthetic electrochemistry [0.03%]
数据科学与合成电化学界面的研究及工作体验
Jesus I Martinez Alvarado,Jonathan M Meinhardt,Song Lin
Jesus I Martinez Alvarado
Electrochemistry is quickly entering the mainstream of synthetic organic chemistry. The diversity of new transformations enabled by electrochemistry is to a large extent a consequence of the unique features and reaction parameters in electr...