Extraction of keratin particles as intact protein sequences from chicken feathers and their characterization [0.03%]
家禽羽毛中角蛋白颗粒的提取及其表征
Julia Chuttke,Luisa Scholz,Johannes Wohlrab et al.
Julia Chuttke et al.
Keratins are ubiquitously occurring proteins, which are the structural basis of e.g. hairs, nails, and even skin. In detail, the Stratum corneum (SC) barrier function depends on the keratin-filled corneocytes and the surrounding lipid matri...
Osteoblast and osteoclast responses to chelate-setting calcium phosphate cements with different solubilities [0.03%]
溶解析出性不同的钙磷水泥对成骨细胞和破骨细胞的生物学效应研究
Minami Kosuge,Kyokei Hazama,Kitaru Suzuki et al.
Minami Kosuge et al.
Artificial bone grafts are widely used to treat bone defects, and paste-type materials capable of setting into arbitrary shapes offer particularly high clinical value. We previously developed a novel paste-type artificial bone, termed a che...
Comparative analysis of different macromolecular crowding agents in human tenocyte cultures [0.03%]
人跟腱细胞培养中不同拥挤剂的比较分析研究
Andrea Rossoni,Giovanni Lauretta,Stephen Kearns et al.
Andrea Rossoni et al.
Tendon engineered substitutes remain clinically unavailable, largely due to the need for prolonged culture periods to allow for sufficient extracellular matrix deposition. Although macromolecular crowding allows for accelerated extracellula...
Durable and biofunctional polydimethylsiloxane surfaces engineered with photocrosslinkable terpolymers for aligned and functional myotube formation [0.03%]
基于光交联三嵌段共聚物的聚二甲基硅氧烷表面工程化促进骨骼肌细胞排列与功能融合的研究
Ryoma Takagi,Tadashi Nakaji-Hirabayashi,Moe Kato et al.
Ryoma Takagi et al.
Polydimethylsiloxane (PDMS) is widely used in biomicrodevices owing to its excellent processability, flexibility, and optical properties. However, the poor cell adhesiveness of PDMS limits its application as a stable substrate for long-term...
Advancing 3D scaffold models for metastatic prostate cancer in bone: Materials, manufacture, and future perspectives [0.03%]
用于骨转移性前列腺癌的三维支架模型的发展：材料、制备及未来展望
Annachiara Dozzo,Aikaterini Dedeloudi,Dimitrios Lamprou et al.
Annachiara Dozzo et al.
The metastatic spread of prostate cancer to the bone is debilitating for patients and is associated with a poor prognostic outlook. Gaining a deeper insight into the pathophysiology of prostate cancer and its metastatic spread using advance...
Superparamagnetic MnFe2O4@Fe2O3 lipid-coated small nanoparticles: Synthesis, physicochemical characterization and biocompatibility assessment in drosophila melanogaster [0.03%]
MnFe2O4@Fe2O3 脂质涂覆超小纳米粒子的合成、物理化学表征及在果蝇中的生物相容性评估
Aline S Perez,Denise Selivon,Antonio M Figueiredo Neto
Aline S Perez
Magnetic nanoparticles (MNPs), particularly manganese ferrite (MnFe2O4), have emerged as promising candidates for biomedical applications due to their tunable magnetic properties, biocompatibility, and functionalization potential. In this s...
Mind the gap: Standardising preclinical testing of bone-repair biomaterials [0.03%]
注重差异：骨修复生物材料非临床试验标准化
Anders Palmquist,Furqan A Shah
Anders Palmquist
The use of bone-repair biomaterials is rapidly expanding to meet the needs of an ageing and increasingly active population, often with compromised bone quality. However, inconsistencies in how materials are assessed preclinically, across an...
Development of biodegradable Fe-Mn thin structures by electroforming in deep eutectic solvents [0.03%]
深共熔溶剂中电铸成型可降解铁锰薄膜结构
Vinicius Sales,Carlo Paternoster,Francesco Copes et al.
Vinicius Sales et al.
Fe-Mn alloys represent promising candidates for temporary biomedical intravascular implants with a thin structure (e.g., coronary, cerebral and peripheral stents) due to their high mechanical strength, acceptable biocompatibility, and contr...
Engineered dermal tissue constructs using mesenchymal stromal cells and TGF-β3-loaded electrospun dressings for stimulated wound healing process [0.03%]
一种用于刺激伤口愈合过程的工程化皮肤组织构建物采用间充质基质细胞和TGF-β3载电纺敷料
Liliana Lizarazo-Fonseca,Gustavo Salguero,Linda Guerrero et al.
Liliana Lizarazo-Fonseca et al.
Transforming growth factor-beta 3 (TGF-β3) has been shown to promote wound healing by regulating key cellular processes. However, its clinical application is limited by the need for repeated dosing and by its labile nature, as TGF-β3 is s...
Evaluating the potential hepatotoxicity from hip implant wear products-An in-vitro and in-vivo study [0.03%]
体外和体内评估髋关节植入物磨损颗粒的潜在肝毒性研究
Shriya Thakur,Hemalatha Kanniyappan,Puranjay Gupta et al.
Shriya Thakur et al.
Total hip replacement (THR) is recognized as an effective treatment for patients suffering from severe arthritis or hip issues, with approximately 2.5 million hip and knee replacements recorded annually (AJJR, 2021). A significant clinical ...