Electrospun poly-4-hydroxybuterate scaffolds enable local zero-order estradiol delivery and promote collagen maturation in a hypoestrogenic rat model for pelvic organ prolapse repair [0.03%]
用于盆腔器官脱垂修复的低雌激素大鼠模型中，静电纺聚4-羟基丁酸酯支架能够实现局部零级结合雌激素递送并促进胶原蛋白成熟
Anel Oosthuysen,Carmen Weitsz,Jan-Paul Wr Roovers et al.
Anel Oosthuysen et al.
Pelvic organ prolapse (POP) affects millions of women globally, with postmenopausal hypoestrogenism playing a critical role in its development. Pelvic floor repair faces two major challenges: high recurrence rates and clinical complications...
Zone of inhibition prediction in silver nanoparticle antimicrobial activity via physics-guided liquid state machine [0.03%]
基于物理的液相机器学习预测银纳米粒子抗菌活性抑菌圈大小
Tanawadee Dechakupt,Chinakrit Akkawong,Santi Bardeeniz et al.
Tanawadee Dechakupt et al.
Silver nanoparticles are widely applied in medicine, packaging, and environmental remediation because of their potent antimicrobial properties. Nevertheless, predictive modeling of their zone of inhibition (ZOI) remains a longstanding chall...
Fabrication of boron-containing apatite ceramics via reaction sintering route and their response of lymphocytes for adoptive immunotherapy [0.03%]
利用反应烧结法制备含硼磷酸钙陶瓷及其对过继免疫治疗淋巴细胞的响应
Y Oshima,D Nakagawa,S Nagai et al.
Y Oshima et al.
Conventional cancer treatments have several challenges, such as side effects and physical decline. Recently, adoptive immunotherapy, which has few side effects, has attracted attention, but the use of expensive drugs has become an issue. In...
Rapid bone formation and remodeling via vascular infiltration of a hydroxyapatite/collagen nanocomposite beneath the calvarial periosteum [0.03%]
羟基磷灰石/胶原纳米复合材料通过血管浸润在颅顶骨膜下快速成骨和改建
Hanae Arai,Masayoshi Uezono,Masanori Kikuchi et al.
Hanae Arai et al.
The development of biomaterials that actively promote bone regeneration remains a major challenge in regenerative medicine and dentistry. This study investigated the time-dependent osteogenic potential of an organic-inorganic composite bone...
Extraction of keratin particles as intact protein sequences from chicken feathers and their characterization [0.03%]
家禽羽毛中角蛋白颗粒的提取及其表征
Julia Chuttke,Luisa Scholz,Johannes Wohlrab et al.
Julia Chuttke et al.
Keratins are ubiquitously occurring proteins, which are the structural basis of e.g. hairs, nails, and even skin. In detail, the Stratum corneum (SC) barrier function depends on the keratin-filled corneocytes and the surrounding lipid matri...
Osteoblast and osteoclast responses to chelate-setting calcium phosphate cements with different solubilities [0.03%]
溶解析出性不同的钙磷水泥对成骨细胞和破骨细胞的生物学效应研究
Minami Kosuge,Kyokei Hazama,Kitaru Suzuki et al.
Minami Kosuge et al.
Artificial bone grafts are widely used to treat bone defects, and paste-type materials capable of setting into arbitrary shapes offer particularly high clinical value. We previously developed a novel paste-type artificial bone, termed a che...
Comparative analysis of different macromolecular crowding agents in human tenocyte cultures [0.03%]
人跟腱细胞培养中不同拥挤剂的比较分析研究
Andrea Rossoni,Giovanni Lauretta,Stephen Kearns et al.
Andrea Rossoni et al.
Tendon engineered substitutes remain clinically unavailable, largely due to the need for prolonged culture periods to allow for sufficient extracellular matrix deposition. Although macromolecular crowding allows for accelerated extracellula...
Durable and biofunctional polydimethylsiloxane surfaces engineered with photocrosslinkable terpolymers for aligned and functional myotube formation [0.03%]
基于光交联三嵌段共聚物的聚二甲基硅氧烷表面工程化促进骨骼肌细胞排列与功能融合的研究
Ryoma Takagi,Tadashi Nakaji-Hirabayashi,Moe Kato et al.
Ryoma Takagi et al.
Polydimethylsiloxane (PDMS) is widely used in biomicrodevices owing to its excellent processability, flexibility, and optical properties. However, the poor cell adhesiveness of PDMS limits its application as a stable substrate for long-term...
Advancing 3D scaffold models for metastatic prostate cancer in bone: Materials, manufacture, and future perspectives [0.03%]
用于骨转移性前列腺癌的三维支架模型的发展：材料、制备及未来展望
Annachiara Dozzo,Aikaterini Dedeloudi,Dimitrios Lamprou et al.
Annachiara Dozzo et al.
The metastatic spread of prostate cancer to the bone is debilitating for patients and is associated with a poor prognostic outlook. Gaining a deeper insight into the pathophysiology of prostate cancer and its metastatic spread using advance...
Superparamagnetic MnFe2O4@Fe2O3 lipid-coated small nanoparticles: Synthesis, physicochemical characterization and biocompatibility assessment in drosophila melanogaster [0.03%]
MnFe2O4@Fe2O3 脂质涂覆超小纳米粒子的合成、物理化学表征及在果蝇中的生物相容性评估
Aline S Perez,Denise Selivon,Antonio M Figueiredo Neto
Aline S Perez
Magnetic nanoparticles (MNPs), particularly manganese ferrite (MnFe2O4), have emerged as promising candidates for biomedical applications due to their tunable magnetic properties, biocompatibility, and functionalization potential. In this s...