Multicountry assessment of tongue swabs for tuberculosis using a common protocol for Xpert MTB/RIF Ultra testing: a prospective diagnostic accuracy study [0.03%]
基于Xpert MTB/RIF Ultra检测的多国舌涂片评估方案:前瞻性诊断准确性研究
Margaretha de Vos,Hien Le,Danaida Marcelo et al.
Margaretha de Vos et al.
Background: Despite advancements in tuberculosis diagnostics, many cases remain unconfirmed because of challenges in conventional sputum-based testing. This study aimed to evaluate the diagnostic accuracy of tongue swab s...
Persistent spread of carbapenemase-producing Klebsiella pneumoniae in acute care hospitals in 36 European countries (the CCRE survey): a prospective, multicentre, cross-sectional, epidemiological, microbiological, and genomic surveillance study [0.03%]
欧洲36个国家急性护理医院产碳青霉烯酶肺炎克雷伯菌的持续传播:前瞻性、多中心、横断面、流行病学、微生物和基因组监测研究(CCRE调查)
Inga Fröding,Sophia David,Corin Yeats et al.
Inga Fröding et al.
Background: Carbapenem-resistant Enterobacterales pose a substantial threat to patients and health-care systems. We conducted a survey of carbapenem-resistant and/or colistin-resistant Enterobacterales (CCRE survey) in 37...
Emergence of carbapenemase-producing Escherichia coli in acute care hospitals in 32 European countries (the CCRE survey): a prospective, multicentre, cross-sectional, epidemiological, microbiological, and genomic surveillance study [0.03%]
欧洲32个国家急性护理医院中产碳青霉烯耐药酶的大肠埃希氏菌的出现:一项前瞻性、多中心、横断面、流行病学、微生物和基因组监测研究(CCRE调查)
Sophia David,Anke Kohlenberg,Corin Yeats et al.
Sophia David et al.
Background: The emergence of carbapenem resistance in Escherichia coli is of major concern due to the high propensity of spread of this species and scarce treatment options. Herein, we examined the occurrence and spread o...
Female genital schistosomiasis, including zoonotic and hybrid schistosomes, and other cervicovaginal co-infections [0.03%]
女性生殖器血吸虫病(包括人畜共患和杂交血吸虫)和其他宫颈阴道合并感染
Olimpia Lamberti,Dingase Kumwenda,Helen Kelly et al.
Olimpia Lamberti et al.
In sub-Saharan Africa, adult women and adolescent girls face a high burden of genital tract co-infections, either by sexual or non-sexual transmission route. Distinguishing between these modes of transmission has important implications for ...
Amy S Sturt,Bodo Randrianasolo,Jennifer A Downs et al.
Amy S Sturt et al.
Schistosomiasis is a neglected tropical disease caused by infection with parasitic worms of the genus Schistosoma. These blood flukes release immunogenic eggs that can become trapped within the body and cause female genital schistosomiasis ...
Tuberculosis needs a multidimensional definition to spur thinking and action [0.03%]
一个多维度的定义能推动结核病防治工作的思考与行动
Anurag Bhargava,Madhavi Bhargava
Anurag Bhargava
Integration of poliovirus and enteropathogen sewage surveillance in Dhaka Bangladesh: a longitudinal surveillance study, June 2019-June 2020 [0.03%]
2019年6月~2020年6月孟加拉国达卡肠道病毒和引起腹泻的病原体污水监测整合研究
Isobel M Blake,Md Ohedul Islam,Benjamin Fuller et al.
Isobel M Blake et al.
Background: The Global Polio Eradication Initiative (GPEI) uses environmental surveillance to monitor circulation of poliovirus. After the certification of poliovirus eradication, environmental surveillance continues, gen...
Evaluating the use of the first WHO International Standard for anti-SARS-CoV-2 immunoglobulin to harmonise the readouts between commercial SARS-CoV-2 binding antibody tests: the HARMONY multicentre calibration study [0.03%]
用于协调商业SARS-CoV-2结合抗体检测结果的首个WHO抗SARS-CoV-2免疫球蛋白国际标准的评价:一项多中心标化研究(HARMONY研究)
Amanda Semper,Peter Rigsby,Ashley Otter et al.
Amanda Semper et al.
Background: The COVID-19 pandemic resulted in the development and use of a plethora of SARS-CoV-2 serology assays, each reporting results in its own assay units, confounding attempts to compare results between different s...
A global economic perspective on whole-genome sequencing strategies for pathogens: continuous surveillance versus outbreak-triggered investigations [0.03%]
全球视角下病原体全基因组测序策略的经济学分析:持续监测与疫情触发调查的成本效益比较
Adrian Egli,Benjamin P Howden
Adrian Egli
Whole-genome sequencing has emerged as a crucial tool for infectious diseases control. Health systems globally are faced with the decision of whether to implement comprehensive genomic surveillance (sequencing all or relevant selected isola...