From vaccination success to new outbreaks: reassessing Japanese encephalitis control in Nepal [0.03%]
从疫苗接种成功到新疫情爆发：重新评估尼泊尔的日本脑炎防控措施
Krishna Prasad Acharya,Francesco Branda,Sarita Phuyal et al.
Krishna Prasad Acharya et al.
Evaluation of bacteriophages as a signature of microbiome health: a systematic review and meta-analysis [0.03%]
噬菌体作为微生物组健康标志物的价值：系统评价和Meta分析
Rachel M Wheatley,Dominique Holtappels,Britt Koskella
Rachel M Wheatley
Background: Parasites are foundational to ecosystem health both as indicator species of community productivity and as drivers of diversity. In bacterial communities, bacteriophage viruses can have such roles as they track...
Determining targets for ceftriaxone resistance detection in Neisseria gonorrhoeae based on genotype-phenotype data: an observational study [0.03%]
基于基因型表型数据确定淋病奈瑟菌中头孢曲松耐药性的目标对象：一项观察性研究
Sebastiaan J van Hal,Monica M Lahra,David M Whiley
Sebastiaan J van Hal
Background: Increasing antimicrobial resistance to ceftriaxone in Neisseria gonorrhoeae presents a public health crisis. We aimed to identify a target associated with ceftriaxone resistance to support the development of r...
Invasive Streptococcus dysgalactiae subspecies equisimilis compared with Streptococcus pyogenes in Australia, 2011-23, and the emergence of a multi-continent stG62647 lineage: a retrospective clinical and genomic epidemiology study [0.03%]
2011年至2023年在澳大利亚侵袭性胆汁链球菌亚种等同相似亚种与群体链球菌的比较，以及多洲stG62647谱系的出现：回顾性临床和基因组流行病学研究
Ouli Xie,Leo Featherstone,An N T Nguyen et al.
Ouli Xie et al.
Background: Streptococcus dysgalactiae subspecies equisimilis (SDSE) is closely related to Streptococcus pyogenes, with overlapping disease manifestations. We compared the clinical and genomic epidemiology of invasive SDS...
Comparative Study
The Lancet. Microbe. 2025 Oct;6(10):101182. DOI:10.1016/j.lanmic.2025.101182 2025
Estimating the association of antimicrobial resistance genes with minimum inhibitory concentration in Escherichia coli: an observational study [0.03%]
一项观察性研究：估计大肠杆菌中抗菌药物耐药基因与最低抑菌浓度的关联性
Samuel Lipworth,Kevin Chau,Sarah Oakley et al.
Samuel Lipworth et al.
Background: Surveillance and prediction of antibiotic resistance in Escherichia coli relies on curated databases of genes and mutations. We aimed to quantify the effect of acquiring specific genetic elements on minimum in...
Revisiting quantitative PCR positivity thresholds to inform the development of shorter benznidazole regimens [0.03%]
重新审视定量PCR阳性阈值以指导开发较短的苯硝唑治疗方案
Qingyu Chen,Zhixuan Zhang,Ruoshu Duan et al.
Qingyu Chen et al.
Duration of the serological response and effectiveness of the inactivated influenza vaccine in healthy adults aged 18-65 years: a systematic review and meta-analysis [0.03%]
甲型和乙型流感灭活疫苗在18至65岁健康成人中的血清学反应持续时间和疫苗效果：系统评价和荟萃分析
Joshua Nazareth,Neyme Veli,Daniel Pan et al.
Joshua Nazareth et al.
Background: The protection provided by the inactivated influenza vaccine (IIV) in adults can wane during a single influenza season. We aimed to assess temporal changes in haemagglutinin inhibition assay (HAI) titres and v...
Priya Venkatesan
Priya Venkatesan
Single-gene transcripts for subclinical tuberculosis: an individual participant data meta-analysis [0.03%]
单基因转录本在亚临床结核病中的作用：个体患者数据分析的meta分析
James Greenan-Barrett,Simon C Mendelsohn,Thomas J Scriba et al.
James Greenan-Barrett et al.
Background: Translation of blood RNA signatures might be accelerated by identifying biomarkers composed of the minimum number of gene transcripts. We aimed to test the hypothesis that single-gene transcripts provide simil...
Rapid pan-microbial metagenomics for pathogen detection and personalised therapy in the intensive care unit: a single-centre prospective observational study [0.03%]
重症监护病房病原菌快速泛微生物宏基因组检测及个性化治疗的单中心前瞻性观察研究
Adela Alcolea-Medina,Luke B Snell,Gul Humayun et al.
Adela Alcolea-Medina et al.
Background: Most clinical metagenomic studies do not provide rapid results, detect pathogens from all microbial kingdoms, or measure clinical impacts. We aimed to evaluate the feasibility, performance, and clinical impact...