What constitutes a healthy vaginal microbiome? Implications for intervention strategies [0.03%]
什么样的阴道菌群是健康的？对干预策略的影响及其意义
Sophie J Miller,Geraint B Rogers
Sophie J Miller
Learning from inconsistencies: refining biomarker discovery in viral diseases [0.03%]
学习不一致性：病毒性疾病生物标志物发现的改进方法
Iva Filipovic,Magda Lourda,Ujjwal Neogi
Iva Filipovic
Acute viral infections of pandemic potential continue to expose major vulnerabilities in global health systems. The heterogeneous clinical trajectories of these infections, ranging from asymptomatic to life-threatening disease, underscore t...
Transmission dynamics of Andes virus and implications for outbreak monitoring [0.03%]
安第斯病毒的传播动力学及其在疫情监测中的应用
Jason R Andrews,Isaac I Bogoch
Jason R Andrews
Paul Adepoju
Paul Adepoju
Multidimensional prophage profiling of carbapenem-resistant Enterobacteriaceae in Thailand: a nationwide, multicentre, genomic study [0.03%]
泰国耐碳青霉烯类肠杆菌科细菌多维度前噬菌体谱系特征研究：一项全国多中心基因组学研究
Ryuichiro Abe,Yo Sugawara,Yukihiro Akeda et al.
Ryuichiro Abe et al.
Background: Prophages influence bacterial fitness, resistance, and evolution, yet their epidemiology remains poorly understood in carbapenem-resistant Enterobacteriaceae (CRE). In this nationwide study in Thailand, we aim...
The Lancet Microbe
The Lancet Microbe
Wastewater-based sequencing of respiratory syncytial virus to investigate lineage dynamics and antigenic site mutations: a retrospective genomic epidemiology study [0.03%]
基于废水的呼吸道合胞病毒测序以研究谱系动态和抗原位点突变：一项回顾性基因组流行病学研究
Jolinda de Korne-Elenbaas,Auguste Rimaite,Ivan Topolsky et al.
Jolinda de Korne-Elenbaas et al.
Background: Respiratory syncytial virus (RSV) infections pose a substantial health burden, particularly for clinically vulnerable populations such as infants and older adults. Although novel immunoprophylactic interventio...
Comparison of phylogenetic metrics of transmission between symptomatic and asymptomatic tuberculosis in individuals who were incarcerated in Brazil in 2008-24: a retrospective genomic epidemiology study [0.03%]
一项关于2008年至2024年在巴西服刑的人员中，有症状和无症状结核病传播的系统发育测度对比的回顾性基因组流行病学研究
Kesia Esther da Silva,Paulo César Pereira Dos Santos,Daniel Henrique Tsuha et al.
Kesia Esther da Silva et al.
Background: Tuberculosis control efforts have traditionally targeted symptomatic individuals; however, the role of asymptomatic cases in sustaining transmission is increasingly recognised. We aimed to quantify the contrib...
Effects of antibiotic treatment on clinical outcomes in patients with COVID-19: a systematic review and meta-analysis [0.03%]
抗生素治疗对COVID-19患者临床结局影响的系统综述和meta分析研究
Daniele Dona,Giulia Brigadoi,Ronaldo Silva et al.
Daniele Dona et al.
Background: The effect of antibiotics on patient-important outcomes in non-severe (NS) and severe or critical (SC) COVID-19 is unclear. We aimed to systematically review and meta-analyse the available evidence on the impa...